Glycosidase inhibitors and uses thereof

Título alternativo: Inhibiteurs de glycosidase et leurs utilisations
Tipo: Patente
Solicitantes:
Simon Fraser University, Canada (33,33%)
CSIC (33,33%)
UNIVERSIDAD DE SEVILLA (33,33%)
Inventores:
Vocadlo, David
García Fernández, José Manuel
Solicitud
25-09-2020
Familia
WO2022064429A1; PCT/IB2021/058706
The invention provides compounds of Formula (I) for inhibiting glycosidases, pro drugs of the compounds, and pharmaceutical compositions comprising the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of OGA, accumulation or deficiency of O-GlcNAc.
Materia: Necesidades corrientes de la vida / Química; Metalurgia
CIP: A61K31/437 (2006.01); A61P11/00 (2006.01); A61P25/28 (2006.01); A61P35/00 (2006.01); A61P37/06 (2006.01); A61P9/00 (2006.01); C07D513/04 (2006.01)
CPC: A61K31/437 (EP); A61P11/00 (EP); A61P25/28 (EP); A61P35/00 (EP); A61P37/06 (EP); A61P9/00 (EP); C07D513/04 (EP)