David Macías Gutiérrez

Profesor Ayudante Doctor
dmaciasg@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología Médica y Biofísica
Grupo: Sin Grupo
Instituto de Inv.: IBIS
Tipo Año Título Fuente
Capítulo2022 Cellular senescence Cellular Senescence in Disease
Artículo2021 Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors INTENSIVE CARE MEDICINE EXPERIMENTAL
Artículo2021 Targeting HIF2 alpha-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension EUROPEAN RESPIRATORY JOURNAL
Artículo2020 2-hydroxyglutarate metabolism is altered in an in vivo model of LPS induced endotoxemia FRONTIERS IN PHYSIOLOGY
Artículo2020 Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity AGING CELL
Artículo2019 Remodeling of bone marrow hematopoietic stem cell niches promotes myeloid cell expansion during premature or physiological aging Cell Stem Cell
Resumen congreso2018 Aging of bone marrow microenvironment promotes myeloid bias of hematopoietic progenitors and is a target in age-related myeloproliferative neoplasms BLOOD
Artículo2018 Glycolytic response to inflammation over time: role of myeloid HIF-1alpha FRONTIERS IN PHYSIOLOGY
Corrección2018 HIF-2 alpha is essential for carotid body development and function eLife
Artículo2018 HIF-2 alpha is essential for carotid body development and function eLife
Artículo2018 The factor inhibiting HIF asparaginyl hydroxylase regulates oxidative metabolism and accelerates metabolic adaptation to hypoxia CELL METABOLISM
Artículo2018 The role of Olfr78 in the breathing circuit of mice NATURE
Artículo2017 An HIF-1 alpha/VEGF-A axis in cytotoxic T cells regulates tumor progression CANCER CELL
Artículo2017 Cardiovascular adaptation to hypoxia and the role of peripheral resistance eLife
Artículo2016 A sensor for low environmental oxygen in the mouse main olfactory epithelium NEURON
Revisión2016 Carotid body oxygen sensing and adaptation to hypoxia PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Artículo2016 HIF2 alpha-arginase axis is essential for the development of pulmonary hypertension PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Revisión2016 Oxygen-sensing by arterial chemoreceptors: mechanisms and medical translation MOLECULAR ASPECTS OF MEDICINE
Artículo2016 S-2-hydroxyglutarate regulates CD8(+) T-lymphocyte fate NATURE
Artículo2016 Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion JOURNAL OF PHYSIOLOGY-LONDON
Artículo2014 Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia EMBO Molecular Medicine
Artículo2014 Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells GLIA
Ponencia2013 Expansion of differentiated GDNF-producing carotid body cells by reversible lentiviral gene transfer. Potential use in cell therapy HUMAN GENE THERAPY
Artículo2010 Identification of a gene involved in the juvenile-to-adult transition (JAT) in cultivated olive trees TREE GENETICS & GENOMES
Resumen congreso2009 A lentiviral vector that activates latent HIV-1 proviruses by the overexpression of TAT and that kills the infected cells HUMAN GENE THERAPY
Artículo2009 A lentiviral vector that activates latent human immunodeficiency virus-1 proviruses by the overexpression of tat and that kills the infected cells HUMAN GENE THERAPY
Resumen congreso2008 A lentiviral vector for regulated tat expression activates HIV-1 silent proviruses in latently infected cells HUMAN GENE THERAPY
Artículo2006 c-Jun kinase mediates expression of VEGF induced at transcriptional level by Rac1 and Cdc42Hs but not by RhoA JOURNAL OF CELLULAR BIOCHEMISTRY
Revisión2005 Gene therapy for HIV-1 infection: are lethal genes a valuable tool? Cellular and Molecular Biology

Este investigador no ha dirigido/tutorizado tesis

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2012 01/01/2014 Investigador/a Convenio de colaboración en materia de apoyo a la transferencia tecnológica en el campo de la biotecnología (CVFB12/005) Fundación Marcelino Botín (Nacional)
01/01/2013 31/12/2015 Investigador/a Sensibilidad al Oxígeno y Neurodegeneración (SAF2012-39343) Ministerio de Economía y Competitividad (Nacional)
13/01/2009 31/12/2013 Investigador/a Síntesis de Ribosomas, Cáncer y Enfermedades Hereditarias. Papel de las Proteínas Ribosómicas y Factores de Ensamblaje de Ribosomas como Posibles Reguladores de la Proliferación Celular (P08-CVI-03508) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/01/2007 31/12/2012 Investigador/a Sensibilidad al oxígeno y neurodegeneración (CONFMB-001/2006) Fundación Marcelino Botín (Nacional)
El investigador no tiene ningún resultado de investigación asociado