Laura Martinez Muñoz

Profesora Contratada Doctora Interina
lmmunoz@us.es
Área de conocimiento: Bioquímica y Biología Molecular
Departamento: Bioquímica Médica y Biología Molecular e Inmunología
Grupo: Sin Grupo
Tipo Año Título Fuente
Artículo2022 Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2021 Fluctuations in AKT and PTEN activity are linked by the E3 ubiquitin ligase cCBL Cells
Artículo2019 Image processing protocol for the analysis of the diffusion and cluster size of membrane receptors by fluorescence microscopy JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
Corrección2018 Erratum: Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function (Molecular Cell (2018) 70(1) (106–119.e10), (S1097276518301795) (10.1016/j.molcel.2018.02.034)) MOLECULAR CELL
Revisión2018 Remodeling our concept of chemokine receptor function: From monomers to oligomers Journal of leukocyte biology
Artículo2018 Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function MOLECULAR CELL
Artículo2017 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4 FASEB JOURNAL
Artículo2017 The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage BLOOD
Artículo2017 Use of lentiviral particles as a cell membrane-based mFasL delivery system for in vivo treatment of inflammatory arthritis FRONTIERS IN IMMUNOLOGY
Capítulo2016 Chemokine detection using receptors immobilized on an SPR sensor surface CHEMOKINES
Capítulo2016 Use of resonance energy transfer techniques for in vivo detection of chemokine receptor oligomerization CHEMOTAXIS: METHODS AND PROTOCOLS
Capítulo2015 Methods to immobilize GPCR on the surface of SPR sensors G PROTEIN-COUPLED RECEPTOR SCREENING ASSAYS: METHODS AND PROTOCOLS
Revisión2015 T cell migration in rheumatoid arthritis FRONTIERS IN IMMUNOLOGY
Artículo2015 Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity FASEB JOURNAL
Artículo2014 CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120(IIIB) binding to the cell surface PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Revisión2013 CXCL12-Mediated Murine Neural Progenitor Cell Movement Requires PI3K beta Activation MOLECULAR NEUROBIOLOGY
Artículo2013 HOMOGENEITY TESTS FOR MICHAELIS-MENTEN CURVES WITH APPLICATION TO FLUORESCENCE RESONANCE ENERGY TRANSFER DATA JOURNAL OF BIOLOGICAL SYSTEMS
Artículo2013 Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2012 Chemokine receptor oligomerization: A further step toward chemokine function IMMUNOLOGY LETTERS
Artículo2012 EBI2 regulates CXCL13-mediated responses by heterodimerization with CXCR5 FASEB JOURNAL
Artículo2012 HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4 JOURNAL OF EXPERIMENTAL MEDICINE
Artículo2011 CD69 Modulates Sphingosine-1-Phosphate-Induced Migration of Skin Dendritic Cells JOURNAL OF INVESTIGATIVE DERMATOLOGY
Revisión2011 Receptor oligomerization: A pivotal mechanism for regulating chemokine function PHARMACOLOGY & THERAPEUTICS
Artículo2011 Technical Advance: Surface plasmon resonance-based analysis of CXCL12 binding using immobilized lentiviral particles Journal of leukocyte biology
Artículo2010 Chemokine receptor oligomerization: functional considerations Current Opinion in Pharmacology
Artículo2009 Chemokine Receptor Dimerization and Chemotaxis CHEMOTAXIS: METHODS AND PROTOCOLS
Artículo2009 Dynamic Regulation of CXCR1 and CXCR2 Homo- and Heterodimers JOURNAL OF IMMUNOLOGY
Revisión2009 MULTIPLE APPROACHES TO THE STUDY OF CHEMOKINE RECEPTOR HOMO- AND HETERODIMERIZATION METHODS IN ENZYMOLOGY, VOL 461: CHEMOKINES, PART B
Artículo2008 Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation European Journal Of Immunology
Artículo2007 Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2007 Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine binds IMMUNITY
Artículo2007 Structures of T cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family IMMUNITY
Artículo2006 RUNX3 negatively regulates CD36 expression in myeloid cell lines JOURNAL OF IMMUNOLOGY
Artículo2006 SOCS up-regulation mobilizes autologous stem cells through CXCR4 blockade BLOOD
Artículo2005 Regulated recruitment of DC-SIGN to cell-cell contact regions during zymosan-induced human dendritic cell aggregation Journal of leukocyte biology
Artículo2004 Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2004 The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor European Journal Of Immunology

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
05/10/2021 31/03/2023 Responsable Estudio de la relevancia funcional de la organización de CXCR4 a nivel nanométrico durante los procesos de extravasación y migración intersticial linfocitaria (P20_00615) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
16/09/2019 15/09/2022 Responsable Identificación del mecanismo molecular que regula la organización espacio-temporal de los receptores de uimioquinas y su relevancia funcional en el tráfico linfocitario. (RTI2018-101789-J-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional)