Antonio Jose Leon Gonzalez

Profesor Ayudante Doctor
ajleon@us.es
Área de conocimiento: Farmacología
Departamento: Farmacología
Grupo: ENDOCRINOLOGIA CELULAR Y MOLECULAR (BIO-139)
Tipo Año Título Fuente
Artículo2021 Clinical, cellular, and molecular evidence of the additive antitumor effects of biguanides and statins in prostate cancer JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Artículo2021 Comparative cytotoxic activity of hydroxytyrosol and its semisynthetic lipophilic derivatives in prostate cancer cells ANTIOXIDANTS
Corrección2021 Correction to: d-Pinitol: a cyclitol with versatile biological and pharmacological activities (Phytochemistry Reviews, (2020), 10.1007/s11101-020-09677-6) Phytochemistry Reviews
Revisión2021 d-Pinitol: a cyclitol with versatile biological and pharmacological activities Phytochemistry Reviews
Artículo2021 Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers. Current Opinion in Pharmacology
Revisión2021 The fruit of Corema album (L.) D. Don, a singular white berry with potential benefits in nutrition and health Phytochemistry Reviews
Artículo2020 Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer EBIOMEDICINE
Artículo2020 Unleashing the diagnostic, prognostic and therapeutic potential of the neuronostatin/GPR107 system in prostate cancer JOURNAL OF CLINICAL MEDICINE
Artículo2019 Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer JOURNAL OF CLINICAL MEDICINE
Artículo2019 Spliceosome component SF3B1 as novel prognostic biomarker and therapeutic target for prostate cancer TRANSLATIONAL RESEARCH
Artículo2018 Anthocyanin-rich bilberry extract induces apoptosis in acute lymphoblastic leukemia cells via redox-sensitive epigenetic modifications JOURNAL OF FUNCTIONAL FOODS
Artículo2018 Genus Retama: a review on traditional uses, phytochemistry, and pharmacological activities Phytochemistry Reviews
Artículo2018 Plasma ghrelin O-acyltransferase (GOAT) enzyme levels: A novel non-invasive diagnosis tool for patients with significant prostate cancer JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Artículo2017 Endothelial Microparticles From Acute Coronary Syndrome Patients Induce Premature Coronary Artery Endothelial Cell Aging and Thrombogenicity Role of the Ang II/AT1 Receptor/NADPH Oxidase-Mediated Activation of MAPKs and PI3-Kinase Pathways CIRCULATION
Artículo2017 EPA:DHA 6:1 prevents angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase- and COX-derived oxidative stress HYPERTENSION RESEARCH
Artículo2017 Lipid Emulsions Containing Medium Chain Triacylglycerols Blunt Bradykinin-Induced Endothelium-Dependent Relaxation in Porcine Coronary Artery Rings LIPIDS
Artículo2017 Phytochemical profile and antibacterial activity of Retama raetam and R. sphaerocarpa cladodes from Algeria NATURAL PRODUCT COMMUNICATIONS
Artículo2017 Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds FOOD & FUNCTION
Artículo2016 Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp. NATURAL PRODUCT COMMUNICATIONS
Artículo2016 Pentacyclic triterpenes responsible for photoprotection of Corema album (L.) D.Don white berries BIOCHEMICAL SYSTEMATICS AND ECOLOGY
Artículo2015 Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway SCIENTIFIC REPORTS
Artículo2015 Chalcones as Promising Lead Compounds on Cancer Therapy CURRENT MEDICINAL CHEMISTRY
Artículo2015 Delphinidin-3-O-glucoside and delphinidin-3-O-rutinoside mediate the redox-sensitive caspase 3-related pro-apoptotic effect of blackcurrant juice on leukaemia Jurkat cells JOURNAL OF FUNCTIONAL FOODS
Artículo2015 Pro-oxidant activity of polyphenols and its implication on cancer chemoprevention and chemotherapy BIOCHEMICAL PHARMACOLOGY
Artículo2014 Anti-inflammatory effects of Retama monosperma in acute ulcerative colitis in rats JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
Artículo2014 Cytotoxic activity of hirsutanone, a diarylheptanoid isolated from Alnus glutinosa leaves PHYTOMEDICINE
Artículo2014 Induction of apoptosis and cell cycle arrest in human colon carcinoma cells by Corema album leaves NATURAL PRODUCT COMMUNICATIONS
Artículo2014 Screening for natural anticancer agents using a fission yeast bioassay PHYTOCHEMISTRY LETTERS
Artículo2013 Cytotoxic activity of dihydrochalcones isolated from corema album leaves against HT-29 colon cancer cells NATURAL PRODUCT COMMUNICATIONS
Artículo2013 Phenolic acids, flavonols and anthocyanins in Corema album (L.) D. Don berries JOURNAL OF FOOD COMPOSITION AND ANALYSIS
Artículo2013 Yeast as a Biosensor of Detoxification: A Tool for Identifying New Compounds that Revert Multidrug Resistance CURRENT DRUG TARGETS
Artículo2012 Chemo-protective activity and characterization of phenolic extracts from Corema album FOOD RESEARCH INTERNATIONAL
Capítulo2012 El uso de crucigramas como método de innovación docente en la asignatura de Farmacia Clínica Estrategias para la enseñanza de la farmacología: experiencias docentes implementadas en España e Iberoamérica
Artículo2012 El uso de crucigramas como método de innovación docente en la asignatura de Farmacia Clínica: XXXIII Congreso Nacional de la SEF: premio Comunicaciones Orales Actualidad en Farmacología y Terapéutica
Revisión2012 Pro-Oxidant Natural Products as Anticancer Agents CURRENT DRUG TARGETS
Ponencia2011 The use of crosswords puzzles as an innovative teaching method for clinical pharmacy BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2008 Cytotoxic activity of extracts from pharmacologically active plants METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
06/07/2011 31/07/2016 Investigador/a Valoración del Aceite de Oliva Virgen Extra en la Artritis Reumatoide Experimental: Estudio Biodirigido, Caracterización Farmacológica y Desarrollo de Ingredientes Funcionales (P10-AGR-6609) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)