José Ignacio Candela Lena

Profesor Titular de Universidad
jicandela@us.es
Área de conocimiento: Química Orgánica
Departamento: Química Orgánica y Farmaceútica
Grupo: ESTEREOQUIMICA Y SINTESIS ASIMETRICA (FQM-102)
Tipo Año Título Fuente
Artículo2016 New 4-Acyl-1-phenylaminocarbonyl-2-phenylpiperazine Derivatives as Potential Inhibitors of Adenovirus Infection. Synthesis, Biological Evaluation, and Structure-activity Relationships JOURNAL OF MEDICINAL CHEMISTRY
Artículo2013 Selective Small Molecule Probes for the Hypoxia Inducible Factor (HIF) Prolyl Hydroxylases ACS CHEMICAL BIOLOGY
Ponencia2012 Kinetic investigations on the reaction of a 2-oxoglutarate dependent histone demethylase with oxygen FEBS JOURNAL
Revisión2008 Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition ORGANIC & BIOMOLECULAR CHEMISTRY
Corrección2008 Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition (vol 6, pg 1665, 2008) ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2007 Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine) and its C(2)-epimer TETRAHEDRON-ASYMMETRY
Artículo2006 Asymmetric synthesis of alpha-mercapto-beta-amino acid derivatives: application to the synthesis of polysubstituted thiomorpholines TETRAHEDRON-ASYMMETRY
Artículo2005 Matched and mismatched pairings in B-secotaxane construction: a structure elucidation study TETRAHEDRON-ASYMMETRY
Artículo2005 Mild protocols for generating molecular complexity: A comparative study of hetero-domino reactions based on the oxidant and the substitution pattern EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2005 The aldol-annulation-fragmentation strategy toward the taxoid diterpene framework revisited. Instructive failures in the chemistry of medium ring containing systems TETRAHEDRON-ASYMMETRY
Artículo2005 Variations of solvent and substitution pattern in Pb(OAc)(4) mediated domino reactions TETRAHEDRON-ASYMMETRY
Artículo2003 An efficient one-pot approach to bridged bicyclic ring-systems through consecutive hetero-domino transformations: A mechanistic rationale and further rearrangements CHEMISTRY-A EUROPEAN JOURNAL
Artículo2003 Lead tetraacetate mediated domino reactions on (R)-(-)-carvone-derived bicyclic unsaturated 1,2-diols and further rearrangements TETRAHEDRON-ASYMMETRY
Artículo2002 Alkylating agents from sugars: Synthesis of chlorambucil derivatives carried by chiral glycosyl glycerols derived from D-glucosamine CHIRALITY
Artículo2002 Iodobenzene diacetate-mediated hetero-domino transformations TETRAHEDRON LETTERS
Artículo2002 Pb(OAc)4 mediated hetero-domino transformations: Can any unsaturated 1,2-diol be regarded as a substrate? TETRAHEDRON LETTERS
Artículo2002 Potential anticancer drugs, Part 6. Stereoselective synthesis of epoxyalkyl glycoside precursors of glycosyl glycerol analogues from alkenyl glycosides of N-acetyl-D-glucosamine derivatives TETRAHEDRON-ASYMMETRY
Artículo2001 A practical access into conveniently functionalized, homochiral C-ring system of taxuyunnanine C TETRAHEDRON-ASYMMETRY
Artículo2001 Oxidative cleavage of unsaturated 1,2-diols using chiral lead-tetracarboxylates obtained by in situ metathesis TETRAHEDRON LETTERS
Artículo2001 Tandem glycol cleavage - Intramolecular 4+2 cycloadditions mediated by Mn(OAc)3 TETRAHEDRON LETTERS
Artículo2001 Tandem glycol cleavage-intramolecular [4+2] cycloadditions mediated by Dess-Martin periodinane SYNLETT
Artículo2000 A rapid entry into major groups of taxoids TETRAHEDRON LETTERS
Artículo2000 Advanced taxoids from Hajos-Parrish ketone and isophorone by the transmetallation (C11-C12)-aldol (C1-C2) approach SYNLETT
Artículo2000 Potential anticancer drugs, 4 - Glycosyl glycerol derivatives as drug carrier system. Stereoselective synthesis of epoxyalkyl N-acyl-beta-D-glucopyranosides and their reactivity with nucleophiles EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2000 Studies towards the taxoid diterpene ABC-ring system: practical access to highly functionalized enantiomerically pure analogues of major group representatives TETRAHEDRON-ASYMMETRY
Artículo1999 Alkylating agents from sugars. Alkyl hexopyranoside derivatives as carrier systems for chlorambucil CARBOHYDRATE RESEARCH
Artículo1999 Alkylating agents from sugars. Stereoselective synthesis of 2,3-diaminoglucoses from 2-nitroalkenes, as intermediates in the synthesis of carriers of chlorambucil TETRAHEDRON
Artículo1999 Influence of the substitution pattern on the Pb(OAc)4 mediated oxidative cleavage of steroidal 1,2-diols TETRAHEDRON-ASYMMETRY
Artículo1999 Modified steroids: Pb(OAc)4 mediated one-pot multistage transformations of steroidal unsaturated 1,2-diols TETRAHEDRON-ASYMMETRY
Artículo1999 Pb(OAc)(4) mediated oxidative cleavage of steroidal unsaturated 1,2-diols: influence of the angular substitution TETRAHEDRON LETTERS
Artículo1999 Study of the m/z [H-1(2)+13](+) ion in 2-aminopyranoside derivatives European Mass Spectrometry (Print)
Artículo1999 Taxoid C-ring building blocks from Hajos-Parrish ketone. Practical synthesis of an enantiomerically pure taxoid ABC ring system TETRAHEDRON-ASYMMETRY
Artículo1997 A facile synthesis of saturated 2-nitrosugar derivatives JOURNAL OF ORGANIC CHEMISTRY
Artículo1996 Mass spectra of N-alkyl and N,N-dialkylaminosugar derivatives. Chemical evidence for the different pathways of fragmentation JOURNAL OF MASS SPECTROMETRY
Artículo1995 A general method for synthesis of alkyl 2-N-substituted and 2-N,N-disubstituted D-altrosamines CARBOHYDRATE RESEARCH
Artículo1995 Electron-impact and chemical-ionization mass-spectra of N-alkyl and N,N-dialkylaminosugar derivatives European Mass Spectrometry (Print)
Artículo1994 A novel general-method for 2-aminoglycal synthesis TETRAHEDRON LETTERS

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/10/2007 30/06/2011 Investigador/a Aplicaciones de carbohidratos y derivados quirales de azufre en las síntesis estereolectivas de compuestos de interés terapéutico (CTQ2007-61185) Ministerio de Educación y Ciencia (Nacional)
30/12/2016 31/12/2020 Investigador/a Desarrollo de Nuevos Sistemas Moleculares y Supramoleculares para una Catálisis Asimétrica Sostenible. Síntesis de Compuestos Antitumorales, Antivíricos y Antibacterianos (CTQ2016-78580-C2-2-R) Ministerio de Economía y Competitividad (Nacional)
13/12/2004 13/12/2007 Investigador/a Síntesis estereoselectivas a partir de organosulfurados y carbohidratos. Aplicaciones de interés terapéutico (CTQ2004-01057) Ministerio de Ciencia y Tecnología (Nacional)
01/01/2014 31/08/2017 Investigador/a Diseño y Síntesis de Nuevos Sistemas Moleculares y Supramoleculares Nanométricos como Herramientas Útiles en Síntesis Asimétrica y Biomedicina (CTQ2013-49066-C2-2-R) Ministerio de Economía y Competitividad (Nacional)
13/04/2007 12/04/2010 Investigador/a Compuestos anticancerosos derivados de azúcares: preparación química y evaluación terapéutica in vitro e in vivo (P06-FQM-01885) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico)
El investigador no tiene ningún resultado de investigación asociado