José Manuel Calderón Montaño

Profesor Ayudante Doctor
Área de conocimiento: Farmacología
Departamento: Farmacología
Grupo: CÁNCER (CTS-657)
Tipo Año Título Fuente
Artículo2021 Carbohydrate-based NK1R antagonists with broad-spectrum anticancer activity. JOURNAL OF MEDICINAL CHEMISTRY
Artículo2021 Cholesterol levels affect the performance of aunps-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery PHARMACEUTICS
Artículo2021 MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia CANCER RESEARCH
Artículo2021 Screening for selective anticancer activity of 65 extracts of plants collected in Western Andalusia, Spain. Plants
Artículo2020 Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29 FOODS
Artículo2020 Meroterpenoids from the brown alga cystoseira usneoides as potential anti-inflammatory and lung anticancer agents MARINE DRUGS
Artículo2019 Screening for selective anticancer activity of plants from Grazalema Natural Park, Spain Natural Product Research
Artículo2018 A 30-s exposure to ethanol 20% is cytotoxic to human keratinocytes: possible mechanistic link between alcohol-containing mouthwashes and oral cancer CLINICAL ORAL INVESTIGATIONS
Letter2018 Are most cancer cases a consequence of an immune deficiency caused by thymic involution? PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículo2018 Avoiding the ingestion of cytotoxic concentrations of ethanol may reduce the risk of cancer associated with alcohol consumption DRUG AND ALCOHOL DEPENDENCE
Artículo2018 Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside DRUG DEVELOPMENT RESEARCH
Artículo2018 The Cockayne syndrome protein B is involved in the repair of 5-AZA-2'-deoxycytidine-induced DNA lesions ONCOTARGET
Artículo2017 A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family NATURE COMMUNICATIONS
Artículo2017 Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017 Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1 JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017 Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017 Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies NATURE MEDICINE
Artículo2017 Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination DNA REPAIR
Artículo2016 Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities CELL REPORTS
Corrección2016 Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities (vol 14, pg 298, 2016) CELL REPORTS
Artículo2016 Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid TOXINS
Artículo2016 Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1 JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015 Antiproliferative Activity of seco-Oxacassanes from Acacia schaffneri NATURAL PRODUCT COMMUNICATIONS
Ponencia2015 Brca2-deficient cells are hypersensitive to cytotoxicity and dna damage induced by the soy isoflavone genistein BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Letter2015 Bufalin Is a Steroid Receptor Coactivator Inhibitor-Letter CANCER RESEARCH
Letter2015 Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer therapy? INVESTIGATIONAL NEW DRUGS
Artículo2015 Effect of DNA repair deficiencies on the cytotoxicity of resveratrol
Artículo2015 In vitro and in vivo evaluation of Delta(9)-tetrahidrocannabinol/PLGA nanoparticles for cancer chemotherapy INTERNATIONAL JOURNAL OF PHARMACEUTICS
Ponencia2014 5-aza-2 ' deoxycytidine induces DNA lesions that are repaired via Transcription-Coupled Repair involving Cockayne syndrome protein B MUTAGENESIS
Revisión2014 Effect of DNA Repair Deficiencies on the Cytotoxicity of Drugs Used in Cancer Therapy - A Review CURRENT MEDICINAL CHEMISTRY
Revisión2014 Evaluating the Cancer Therapeutic Potential of Cardiac Glycosides BIOMED RESEARCH INTERNATIONAL
Artículo2014 Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Letter2014 The in vivo antitumor activity of cardiac glycosides in mice xenografted with human cancer cells is probably an experimental artifact ONCOGENE
Artículo2014 The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2 '-deoxycytidine lesions NUCLEIC ACIDS RESEARCH
Ponencia2014 Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by Homologous Recombination MUTAGENESIS
Artículo2013 5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair NUCLEIC ACIDS RESEARCH
Artículo2013 A Hydroalcoholic Extract from the Leaves of Nerium oleander Inhibits Glycolysis and Induces Selective Killing of Lung Cancer Cells PLANTA MEDICA
Artículo2013 Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death TOXICOLOGY LETTERS
Artículo2013 Aziridines from alkenyl-beta-D-galactopyranoside derivatives: Stereoselective synthesis and in vitro selective anticancer activity EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Letter2013 Comment on 'Quiescence and gamma H2AX in neuroblastoma are regulated by Ouabain/Na,K-ATPase': ouabain and cancer BRITISH JOURNAL OF CANCER
Artículo2013 Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data
Artículo2013 Dichloroacetate, 2-Deoxyglucose and a Hydroalcoholic Extract from the Skin of the Fruit of Solanum melongena (Aubergine) Induce Selective Anticancer Activity against Melanoma Cells
Artículo2013 Selective Cytotoxic Activity of New Lipophilic Hydroxytyrosol Alkyl Ether Derivatives JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2013 The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells
Artículo2013 Vitamin C and the Red Wine Polyphenol Resveratrol - but not Curcumin and the Glycolysis Inhibitors 2- Deoxyglucose, Dichloroacetate and 3-Bromopyruvate - Induce Selective Cytotoxicity against Lung Cancer Cells.
Artículo2012 Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death PHARMACOLOGICAL REPORTS
Revisión2012 Pro-Oxidant Natural Products as Anticancer Agents CURRENT DRUG TARGETS
Artículo2012 Stereoselective Dihydroxylation Reaction of Alkenyl ss-D-Hexopyranosides: A Methodology for the Synthesis of Glycosylglycerol Derivatives and 1-O-Acyl-3-O-ss-D-glycosyl-sn-glycerol Analogues EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2012 The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I- and II-DNA Complexes in Cells JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Revisión2011 A review on the dietary flavonoid kaempferol MINI-REVIEWS IN MEDICINAL CHEMISTRY
Artículo2011 Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide MUTAGENESIS
Letter2011 More research is needed to establish the benefit-risk profile of curcumin INTERNATIONAL JOURNAL OF CANCER
Artículo2011 Role of the Intracellular pH in the Metabolic Switch between Oxidative Phosphorylation and AerobicGlycolysis - Relevance to Cancer
Letter2010 The dark side of curcumin INTERNATIONAL JOURNAL OF CANCER

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
05/10/2021 31/12/2022 Investigador/a Fármacos multidiana estructuralmente relacionados con isotiocianatos naturales: diseño, síntesis y aplicaciones terapéuticas (P20_01171) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
30/01/2014 31/07/2018 Investigador/a Interés de los Polifenoles en Inflamación Crónica y Cáncer: Papel en los Sistemas Celulares de Regulación Mitocondrial y del Inflamasoma. Polfanat-II (P12-AGR-430) Consejería de Economía, Innovación y Ciencia (Autonómico)
01/06/2020 31/05/2023 Investigador/a Los Carbohidratos y el Azufre como Herramientas Básicas en el Diseño y Síntesis de Nuevos Sistemas Moleculares Privilegiados de Interés Terapéutico y/o Sintético (PID2019-104767RB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional)
30/12/2016 31/12/2020 Investigador/a Transcription y Replication como Fuentes de Inestabilidad Genética (BFU2016-75058-P) Ministerio de Economía y Competitividad (Nacional)
01/01/2014 30/06/2017 Investigador/a Inestabilidad Genómica Asociada a Transcripción e Híbridos DNA-RNA (BFU2013-42918-P) Ministerio de Economía y Competitividad (Nacional)


Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
31/12/2020 31/12/2022 Investigador/a Importancia de MYCN en la sensibilidad en células madre de neuroblastoma a inhibidores de MTH1 (4045/1078) NEN - Asociación de familias y amigos de pacientes enfermos de neuroblastoma (Nacional)
30/06/2018 29/06/2022 Investigador/a Dietas artificiales basadas en restricciones selectivas de aminoácidos para el tratamiento de cánceres metastásicos (3388/0836) AMINOVITA, S.L. (Local)
01/07/2016 31/12/2017 Investigador/a Evaluación preclinica de nuevas estrategias anticancerosas orientadas al paciente oncológico (2812/0836) Asociación para el Desarrollo de la Oncología (ADEON) (Local)


Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/06/2013 31/08/2013 Responsable Evaluación del daño en el ADN inducido por una nueva aziridina (PP2013-814) Universidad de Sevilla (Local)


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