Sandro Arguelles Castilla

Profesor Contratado Doctor
sarguelles1@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología
Grupo: BIOQUIMICA DEL ENVEJECIMIENTO (BIO-158)
Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)
Tipo Año Título Fuente
Artículo2021 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). AUTOPHAGY
Capítulo2021 Hydroxytyrosol, olive oil, and use in aging OLIVES AND OLIVE OIL IN HEALTH AND DISEASE PREVENTION
Artículo2020 Effect of age and lipoperoxidation in rat and human adipose tissue-derived stem cells OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
Revisión2020 Map kinase signaling as therapeutic target for neurodegeneration PHARMACOLOGICAL RESEARCH
Revisión2020 Oral microbiota and Alzheimer's disease: Do all roads lead to Rome? PHARMACOLOGICAL RESEARCH
Artículo2019 Adipose-derived stem cells decreased microglia activation and protected dopaminergic loss in rat lipopolysaccharide model JOURNAL OF CELLULAR PHYSIOLOGY
Revisión2019 Advantages and disadvantages of apoptosis in the aging process ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Artículo2019 Bee Products: Royal Jelly and Propolis NONVITAMIN AND NONMINERAL NUTRITIONAL SUPPLEMENTS
Revisión2019 Dysregulation of the Hippo pathway signaling in aging and cancer PHARMACOLOGICAL RESEARCH
Ponencia2019 Elaboración de un tríptico sobre aspectos relevantes de las asignaturas impartidas por el departamento de fisiología de la Universidad de Sevilla Evaluación de la calidad de la investigación y de la educación superior: XVI FECIES. Libro de actas
Revisión2019 Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and neurodegenerative diseases PHARMACOLOGICAL RESEARCH
Revisión2019 Phosphodiesterase inhibitors say NO to Alzheimer's disease FOOD AND CHEMICAL TOXICOLOGY
Artículo2019 Physical exercise and myokines APPROACHES TO AGING CONTROL
Revisión2019 Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders PHARMACOLOGICAL RESEARCH
Artículo2019 Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds FOOD AND CHEMICAL TOXICOLOGY
Revisión2019 Targeting STATs in neuroinflammation: The road less traveled! PHARMACOLOGICAL RESEARCH
Artículo2019 Uric acid enhances longevity and endurance and protects the brain against ischemia NEUROBIOLOGY OF AGING
Revisión2018 Apigenin as neuroprotective agent: Of mice and men PHARMACOLOGICAL RESEARCH
Artículo2018 Cell tracking, survival, and differentiation capacity of adipose-derived stem cells after engraftment in rat tissue JOURNAL OF CELLULAR PHYSIOLOGY
Editorial2018 Current advances in pharmacotherapy and drug design against inflammatory-related pathologies CURRENT PHARMACEUTICAL DESIGN
Revisión2018 Signaling Pathways in Inflammation and Anti-inflammatory Therapies CURRENT PHARMACEUTICAL DESIGN
Artículo2018 Targeting ERK signaling pathway by polyphenols as novel therapeutic strategy for neurodegeneration FOOD AND CHEMICAL TOXICOLOGY
Revisión2018 Targeting mTORs by omega-3 fatty acids: A possible novel therapeutic strategy for neurodegeneration? PHARMACOLOGICAL RESEARCH
Artículo2017 Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide JOURNAL OF CELLULAR BIOCHEMISTRY
Revisión2017 Application of Kinase Inhibitors for Anti-aging Intervention CURRENT PHARMACEUTICAL DESIGN
Capítulo2017 Rendimiento académico del alumnado al utilizar nuevas tecnologías para evaluar las competencias en un laboratorio de prácticas Evaluación de la Calidad de la Investigación y de la Educación Superior: Libro de resúmenes XIV FECIES
Artículo2016 Hialuronic acid in sking aging Medicina Antienvejecimiento
Artículo2015 Advanced therapy medicinal products: Gene therapy Pharmaceuticals Policy and Law
Editorial2015 Current Advances in Biochemistry, Medicinal Chemistry and Drug Development Strategies for Age-Related Neurodegenerative Diseases CURRENT TOPICS IN MEDICINAL CHEMISTRY
Artículo2015 Synergistic Deleterious Effect of Chronic Stress and Sodium Azide in the Mouse Hippocampus CHEMICAL RESEARCH IN TOXICOLOGY
Artículo2015 Treatment with mesenchymal stem cells in an animal model of parkinson's disease APPROACHES TO AGING CONTROL
Artículo2014 Chronic stress as a risk factor for Alzheimer's disease REVIEWS IN THE NEUROSCIENCES
Ponencia2014 Effects of aging and oxidative stress on elongation factor-2 in the pineal gland and its protection by melatonin ACTA PHYSIOLOGICA
Artículo2014 Elongation factor 2 diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative Stress conditions FREE RADICAL BIOLOGY AND MEDICINE
Revisión2014 Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
Artículo2013 Molecular control of the amount, subcellular location, and activity state of translation elongation factor 2 in neurons experiencing stress FREE RADICAL BIOLOGY AND MEDICINE
Capítulo2012 Assessment of the general oxidant status of individuals in non-invasive samples Oxidative Stress - Molecular Mechanisms and Biological Effects
Artículo2012 Folic acid supplementation: some practical aspects APPROACHES TO AGING CONTROL
Artículo2012 In vitro and in vivo protection by melatonin against the decline of elongation factor-2 caused by lipid peroxidation: preservation of protein synthesis JOURNAL OF PINEAL RESEARCH
Artículo2012 Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system NEUROTOXICOLOGY
Artículo2012 Potential use of adipose tissue stem cells in the control of aging APPROACHES TO AGING CONTROL
Artículo2011 Effect of aging and oxidative stress on elongation factor-2 in hypothalamus and hypophysis MECHANISMS OF AGEING AND DEVELOPMENT
Artículo2011 Inflammatory animal models for parkinson's disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons ISRN Neurology
Revisión2011 Peripheral Inflammation Increases the Damage in Animal Models of Nigrostriatal Dopaminergic Neurodegeneration: Possible Implication in Parkinson's Disease Incidence PARKINSONS DISEASE
Artículo2011 Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus NEUROBIOLOGY OF AGING
Artículo2010 Comparative Study of the in Vitro Protective Effects of Several Antioxidants on Elongation Factor 2 under Oxidative Stress Conditions BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Artículo2010 Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: Role of monoamine oxidase enzyme NEUROTOXICOLOGY
Ponencia2010 Effect of aging and oxidative stress on elongation factor-2 in hypothalamus and hypophysis FEBS JOURNAL
Artículo2010 Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson's disease JOURNAL OF NEUROCHEMISTRY
Artículo2010 Use of haptoglobin and transthyretin as potential biomarkers for the preclinical diagnosis of Parkinson's disease NEUROCHEMISTRY INTERNATIONAL
Artículo2009 Adduct formation of 4-hydroxynonenal and malondialdehyde with elongation factor-2 in vitro and in vivo FREE RADICAL BIOLOGY AND MEDICINE
Artículo2009 The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat NEUROTOXICOLOGY
Artículo2008 Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide JOURNAL OF NEUROCHEMISTRY
Artículo2007 'In vitro' protective effect of a hydrophilic vitamin e analogue on the decrease in levels of elongation factor 2 in conditions of oxidative stress GERONTOLOGY
Artículo2007 A preliminary analysis of within-subject variation in human serum oxidative stress parameters as a function of time REJUVENATION RESEARCH
Artículo2007 Proteomic identification of biomarkers in the cerebrospinal fluid in a rat model of nigrostriatal dopaminergic degeneration JOURNAL OF NEUROSCIENCE RESEARCH
Artículo2006 "In vitro" effect of lipid peroxidation metabolites on elongation factor-2 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2006 Correlation between circulating biomarkers of oxidative stress of maternal and umbilical cord blood at birth FREE RADICAL RESEARCH
Artículo2006 Oxidative stress is increased in critically ill patients according to antioxidant vitamins intake, independent of severity: a cohort study CRITICAL CARE
Artículo2006 Stress increases vulnerability to inflammation in the rat prefrontal cortex JOURNAL OF NEUROSCIENCE
Artículo2005 Effects of short-term supplementation with folic acid on different oxidative stress parameters in patients with hypertension BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2004 Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status? BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo2003 Comparison of methods for sample preparation of individual rat cerebrospinal fluid samples prior to two-dimensional polyacrylamide gel electrophoresis BIOTECHNOLOGY LETTERS
Artículo2003 Effect of prenatal exposure to ethanol on hepatic elongation factor-2 and proteome in 21 D old rats: Protective effect of folic acid FREE RADICAL BIOLOGY AND MEDICINE

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2010 31/12/2010 Investigador/a Implicación de las interacciones de las rutas que aumentan la vida media y la supervivencia celular con el factor de elongación 2 en el mantenimiento de la síntesis de proteínas durante el envejecimiento (BFU2009-12307) Ministerio de Ciencia e Innovación (Nacional)
01/01/2011 31/12/2013 Investigador/a Significado Biológico de la Integración de los distintos Mecanismos de Regulación del Factor de Elongación-2 en Condiciones de Estrés Celular y Envejecimiento (BFU2010-20882) Ministerio de Ciencia e Innovación (Nacional)
15/03/2011 30/04/2016 Investigador/a Estudio de los Mecanismos Moleculares que Regulan la Inflamación Cerebral y la Longevidad. Diseño de Estrategias Farmacológicas Encaminadas a Minimizar el Daño Neuronal Asociado a la Inflamación Cerebral en Modelos Animales de Enfermedades Neurodegenerativas (P10-CTS-6494) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/01/2004 31/03/2007 Investigador/a Estudio del mecanismo de inhibición de la síntesis de proteínas por el envejecimiento y el estrés oxidativo y prevención de esta inhibición mediante el uso de compuestos antioxidantes y protectores (PI031233) Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III) (Nacional)
01/03/2006 28/02/2009 Investigador/a La enfermedad de Parkinson: Diagnostico en estado subclinico (EXC/2005/CTS-1014) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico)
01/10/2006 30/09/2009 Investigador/a Influencia del mantenimiento de la síntesis de proteínas durante el envejecimiento en el aumento del plazo de vida causado por la restricción claorica: importancia del factor de elongación 2 (BFU2006-06517) Ministerio de Educación y Ciencia (Nacional)
03/03/2011 03/03/2015 Investigador/a Estudio de los Cambios que Experimentan con el Envejecimiento las Rutas que Promueven la Supervivencia Celular y la Inflamación Cerebral: Modulación de las Mismas para Conseguir un Envejecimiento Saludable y Minimizar la Neurodegeneración (P09-CTS-5244) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)