Tarik Smani Hajami

Profesor Titular de Universidad
tasmani@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología Médica y Biofísica
Grupo: TRASPLANTE CORAZON. CONSERVACION CORAZON DONANTE (CTS-200)
Instituto de Inv.: IBIS
Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)
Tipo Año Título Fuente
Revisión2021 Ca2+ mishandling in heart failure: potential targets ACTA PHYSIOLOGICA
Artículo2021 Clinical impact of rotational thromboelastometry in cardiac surgery Transfusion Clinique et Biologique
Corrección2021 Corrigendum: SARAF and Orai1 contribute to endothelial cell activation and angiogenesis (Frontiers in Cell and Developmental Biology, (2021), 9, (639952), 10.3389/fcell.2021.639952) FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Editorial2021 Editorial: Involvements of TRP channels, oxidative stress and apoptosis in neurodegenerative diseases FRONTIERS IN PHYSIOLOGY
Artículo2021 Furin frodomain ppFurin enhances Ca2+ entry through Orai and TRPC6 channels' activation in breast cancer cells CANCERS
Artículo2021 Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple negative breast cancer cells JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2021 miR-30b-5p downregulation as a predictive biomarker of coronary in-stent restenosis. Biomedicines
Artículo2021 SARAF and EFHB modulate store-operated Ca2+ entry and are required for cell proliferation, migration and viability in breast cancer cells CANCERS
Artículo2021 SARAF and Orai1 contribute to endothelial cell activation and angiogenesis FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
Artículo2020 Circulating miR-320a as a Predictive Biomarker for Left Ventricular Remodelling in STEMI Patients Undergoing Primary Percutaneous Coronary Intervention JOURNAL OF CLINICAL MEDICINE
Revisión2020 Innate Immune Receptors, Key Actors in Cardiovascular Diseases JACC: Basic to Translational Science
Artículo2020 Molecular Basis and Regulation of Store-Operated Calcium Entry Advances in Experimental Medicine and Biology
Capítulo2020 Non-coding RNAs and ischemic vardiovascular diseases Non-coding RNAs in Cardiovascular Diseases
Artículo2020 Pathophysiological Significance of Store-Operated Calcium Entry in Cardiovascular and Skeletal Muscle Disorders and Angiogenesis Advances in Experimental Medicine and Biology
Artículo2020 Podoplanin Gene Disruption in Mice Promotes in vivo Neural Progenitor Cells Proliferation, Selectively Impairs Dentate Gyrus Synaptic Depression and Induces Anxiety-Like Behaviors FRONTIERS IN CELLULAR NEUROSCIENCE
Artículo2020 Role of Orai1 and L-type CaV1.2 channels in Endothelin-1 mediated coronary contraction under ischemia and reperfusion CELL CALCIUM
Revisión2020 TRPC and TRPV channels' role in vascular remodeling and disease INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Revisión2020 TRPC Channels in the SOCE Scenario Cells
Revisión2020 TRPC Channels: dysregulation and Ca2+ mishandling in ischemic heart disease Cells
Artículo2019 Adenylyl cyclase type 8 overexpression impairs phosphorylation-dependent orai1 inactivation and promotes migration in MDA-MB-231 breast cancer cells CANCERS
Revisión2019 Impact of Diabetes on Cardiac and Vascular Disease: Role of Calcium Signaling CURRENT MEDICINAL CHEMISTRY
Artículo2019 STIM1 phosphorylation at Y316 modulates its interaction with SARAF and the activation of SOCE and ICRAC JOURNAL OF CELL SCIENCE
Revisión2019 TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling FRONTIERS IN PHYSIOLOGY
Ponencia2018 Circulating miRNAs associated with acute myocardial infarction treated with primary percutaneous coronary intervention CARDIOVASCULAR RESEARCH
Artículo2018 EFHB is a Novel Cytosolic Ca2+ Sensor That Modulates STIM1-SARAF Interaction CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
Artículo2018 Filamin A Modulates Store-Operated Ca2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Ponencia2018 miR-324 contributes to Urocortin modulation of apoptosis during myocardial ischemia and reperfusion CARDIOVASCULAR RESEARCH
Artículo2018 miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation MOLECULAR THERAPY-NUCLEIC ACIDS
Revisión2018 The Complex Role of Store Operated Calcium Entry Pathways and Related Proteins in the Function of Cardiac, Skeletal and Vascular Smooth Muscle Cells FRONTIERS IN PHYSIOLOGY
Revisión2018 TRP Channels in Angiogenesis and Other Endothelial Functions FRONTIERS IN PHYSIOLOGY
Artículo2018 TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure CANCERS
Artículo2018 Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion FRONTIERS IN PHYSIOLOGY
Ponencia2017 Ca(v)1.2 L-type Ca2+ channel form a signal complex with Orai1 and TRPC1 in vascular smooth muscle cells: Role in vascular tone regulatio ACTA PHYSIOLOGICA
Artículo2017 miR-125a, miR-139 and miR-324 contribute to Urocortin protection against myocardial ischemia-reperfusion injury SCIENTIFIC REPORTS
Ponencia2017 Role of altered Ca2+ homeostasis during adverse cardiac remodeling after ischemia and reperfusion ACTA PHYSIOLOGICA
Ponencia2017 The brain-tumor related protein podoplanin regulates synaptic plasticity and hippocampus-dependent learning and memory ACTA PHYSIOLOGICA
Revisión2017 TRPs in pain sensation FRONTIERS IN PHYSIOLOGY
Artículo2016 Cardioprotective Effect of Ranolazine in the Process of Ischemia-reperfusion in Adult Rat Cardiomyocytes Revista Española de Cardiología
Artículo2016 Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry SCIENTIFIC REPORTS
Revisión2016 Molecular modulators of store-operated calcium entry BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo2016 Orai1 and TRPC1 Proteins Co-localize with Ca(V)1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells JOURNAL OF BIOLOGICAL CHEMISTRY
Capítulo2016 Phospholipase A2as a molecular determinant of store-operated calcium entry Advances in Experimental Medicine and Biology
Artículo2016 Regulation of Platelet Function by Orai, STIM and TRP Advances in Experimental Medicine and Biology
Ponencia2016 Role of altered Ca2+homeostasis during adverse cardiac remodeling after ischemia/reperfusion CARDIOVASCULAR RESEARCH
Revisión2016 STIM and Orail Variants in Store-Operated Calcium Entry FRONTIERS IN PHARMACOLOGY
Artículo2016 The brain-tumor related protein podoplanin regulates synaptic plasticity and hippocampus-dependent learning and memory ANNALS OF MEDICINE
Artículo2016 Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2 PLOS ONE
Ponencia2016 Urocortin-1 promotes cardioprotection through ERK1/2 and EPAC pathways: role in apoptosis and necrosis CARDIOVASCULAR RESEARCH
Revisión2015 Functional and physiopathological implications of TRP channels BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo2015 Homer proteins mediate the interaction between STIM1 and Ca(v)1.2 channels BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo2015 Resveratrol Ameliorates the Maturation Process of beta- Cell-Like Cells Obtained from an Optimized Differentiation Protocol of Human Embryonic Stem Cells PLOS ONE
Ponencia2015 Urocortin-1 preserve XIAP and CD40-ligand to reduce ischemia/reperfusion-induced cardiac myocyte apoptosis via the activation of ERK1/2 through EPAC EUROPEAN HEART JOURNAL
Revisión2014 Cytoskeletal and scaffolding proteins as structural and functional determinants of TRP channels BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Ponencia2014 EMERGING ROLE OF TRP AND STORE OPERATED CHANNELS IN THE CARDIOVASCULAR SYSTEM. ACTA PHYSIOLOGICA
Ponencia2014 Evaluation of Urotensin-II and Urocortin as biomarkers of myocardial damage in an animal model of acute myocardial infarction ACTA PHYSIOLOGICA
Ponencia2014 Functional crosstalk between L-type Ca2+and Orai1 channels and their regulation of vascular tone ACTA PHYSIOLOGICA
Ponencia2014 Urotensin-II Induces Vascular Smooth Muscle Cell Proliferation and Creb Phosporylation Through Store Operated Calcium Entry and EGFR Transactivation BIOPHYSICAL JOURNAL
Artículo2013 Functional Vascular Smooth Muscle-like Cells Derived from Adult Mouse Uterine Mesothelial Cells PLOS ONE
Artículo2013 New Insights into the Mechanisms Underlying Vascular and Cardiac Effects of Urocortin CURRENT VASCULAR PHARMACOLOGY
Letter2013 Radial and circumferential strain as markers of fibrosis in an experimental model of myocardial infarction Revista Española de Cardiología
Editorial2013 Recent Advances in Cardiovascular and Circulatory Signalling CURRENT VASCULAR PHARMACOLOGY
Artículo2013 Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca2+ entry by regulation of STIM1-Orai1 association BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo2013 Urotensin-II promotes vascular smooth muscle cell proliferation through store-operated calcium entry and EGFR transactivation CARDIOVASCULAR RESEARCH
Artículo2012 Cardiotrophin-1 induces sarcoplasmic reticulum Ca-2 leak and arrhythmogenesis in adult rat ventricular myocytes CARDIOVASCULAR RESEARCH
Artículo2012 Urotensin-II Signaling Mechanism in Rat Coronary Artery Role of STIM1 and Orai1-Dependent Store Operated Calcium Influx in Vasoconstriction ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Artículo2011 Association Analysis of Urotensin II Gene (UTS2) and Flanking Regions with Biochemical Parameters Related to Insulin Resistance PLOS ONE
Artículo2011 Cardioprotective action of urocortin in postconditioning involves recovery of intracellular calcium handling CELL CALCIUM
Ponencia2011 Essential Role of Store-Operated Calcium Entry in Urotensin-Ii Induced Vascular Smooth Muscle Cells Proliferation BIOPHYSICAL JOURNAL
Revisión2011 Immunophilins and Cardiovascular Complications CURRENT MEDICINAL CHEMISTRY
Artículo2011 The cytoskeleton plays a modulatory role in the association between STIM1 and the Ca2+ channel subunits Orai1 and TRPC1 BIOCHEMICAL PHARMACOLOGY
Artículo2011 Urocortin-2 induces vasorelaxation of coronary arteries isolated from patients with heart failure CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Artículo2010 Mechanisms underlying the activation of L-type calcium channels by urocortin in rat ventricular myocytes CARDIOVASCULAR RESEARCH
Ponencia2010 Regulation of Vascular Reactivity by Urocortin and Urotensin-II: Role of Store Operated Pathway BIOPHYSICAL JOURNAL
Artículo2009 Urocortin induces positive inotropic effect in rat heart CARDIOVASCULAR RESEARCH
Artículo2008 Complex regulation of store-operated Ca2+ entry pathway by PKC-epsilon in vascular SMCs AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Ponencia2008 Positive inotropic effect of Urocortin on cardiomyocytes: Role of L-type calcium channels JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Ponencia2008 Urocortin induces heart protection against ischemia-reperfusion injury PROCEEDINGS OF THE XXVIII EUROPEAN SECTION MEETING OF THE INTERNATIONAL SOCIETY FOR HEART RESEARCH
Artículo2007 Role of Ca2+-independent phospholipase A(2) and store-operated pathway in urocortin-induced vasodilatation of rat coronary artery CIRCULATION RESEARCH
Artículo2006 Activation mechanism for CRAC current and store-operated Ca2+ entry - Calcium influx factor and Ca2+-independent phospholipase A(2)beta-mediated pathway JOURNAL OF BIOLOGICAL CHEMISTRY
Ponencia2005 Complex regulation of store-operated Ca2+ influx pathway by PKC and DAG: dependence on iPLA(2) and cell proliferation. BIOPHYSICAL JOURNAL
Ponencia2005 Disruption of lipid rafts inhibits store-operated Ca2+ influx by impairing lysophospholipid-mediated communication between iPLA(2) and SOC channels. BIOPHYSICAL JOURNAL
Ponencia2005 iPLA(2) - dependent regulation of I-CRAC and store-operated calcium influx in RBL cells. BIOPHYSICAL JOURNAL
Artículo2004 A novel mechanism for the store-operated calcium influx pathway NATURE CELL BIOLOGY
Ponencia2004 Activation of store-operated (capacitative) Ca2+ influx is mediated by lysophospholipid products of iPLA(2)beta, but not iPLA(2)gamma FASEB JOURNAL
Ponencia2004 Diethylstilbestrol (DES) is a potent inhibitor of CRAC channels and store-operated Ca2+ influx. BIOPHYSICAL JOURNAL
Artículo2004 Diethylstilbestrol is a potent inhibitor of store-operated channels and capacitative ca2+ influx MOLECULAR PHARMACOLOGY
Artículo2004 Differential functional properties of Ca2+ stores in pulmonary arterial conduit and resistance myocytes CELL CALCIUM
Ponencia2004 Lysophospholipid products of iPLA(2)-beta, but not iPLA(2)-gamma, mediate activation of store-operated channels and capacitative calcium influx. BIOPHYSICAL JOURNAL
Ponencia2004 Novel mechanism of store-operated Ca2+ influx pathway FASEB JOURNAL
Ponencia2004 Regulation of store-operated Ca2+ influx by diacylglycerol and PKC may be mediated by Ca2+-independent phospholipase A(2). FASEB JOURNAL
Ponencia2003 Ca-2(2+-independent phospholipase A) is a crucial molecular determinant in store-operated Ca2+influx pathway. BIOPHYSICAL JOURNAL
Artículo2003 Ca2+-independent phospholipase A(2) is a novel determinant of store-operated Ca2+ entry JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2003 Monovalent cation (MC) current in cardiac and smooth muscle cells: regulation by intracellular MG2+ and inhibition by polycations BRITISH JOURNAL OF PHARMACOLOGY
Ponencia2003 Novel mechanism of CaM- and iPLA(2)-dependent activation of store-operated channels. BIOPHYSICAL JOURNAL
Ponencia2002 Comparative analysis of I-CRAC and hidden monovalent cation (MC) current in cardiovascular system BIOPHYSICAL JOURNAL
Artículo2002 Reduction of Ca2+ channel activity by hypoxia in human and porcine coronary myocytes CARDIOVASCULAR RESEARCH
Ponencia2002 Regulation of the hidden monovalent cation (MC) current by intracellular Mg2+, extracellular polyamines and 2-APB BIOPHYSICAL JOURNAL
Ponencia2002 Store-operated and TRP channels, calciul influx factor and calmodulin in smooth muscle cells BIOPHYSICAL JOURNAL
Artículo2001 Differential segmental activation of Ca2+-dependent Cl- and K+ channels in pulmonary arterial myocytes CELL CALCIUM
Artículo1999 K+ and Ca2+ channel activity and cytosolic [Ca2+] in oxygen-sensing tissues RESPIRATION PHYSIOLOGY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/06/2020 31/05/2023 Responsable Remodelado de la Expresión de Stim y Orai y de sus Mecanismos Reguladores en la Angiogenesis (PID2019-104084GB-C22) Ministerio de Ciencia, Innovación y Universidades (Nacional)
30/12/2016 31/12/2020 Responsable Remodelado de la Entrada de Calcio en la Angiogenesis (BFU2016-74932-C2-2-P) Ministerio de Economía y Competitividad (Nacional)
01/01/2014 31/12/2017 Responsable Regulación de la Entrada de Calcio en Células Excitables y Papel de Proteínas Stim, Orai y Trp en la Proliferación Celular y en el Remodelado Vascular (BFU2013-45564-C2-2-P) Ministerio de Economía y Competitividad (Nacional)