Víctor Sánchez Margalet

Catedrático de Universidad (V)
margalet@us.es
Área de conocimiento: Bioquímica y Biología Molecular
Departamento: Bioquímica Méd.y Biol.Molecular e Inmun.
Grupo: BIOQUIMICA MEDICA (CTS-151)
Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)
Tipo Año Título Fuente
Artículo2021 Circulating immune biomarkers in peripheral blood correlate with clinical outcomes in advanced breast cancer SCIENTIFIC REPORTS
Artículo2021 Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: Translational results from the R2-GDP-GOTEL trial JOURNAL FOR IMMUNOTHERAPY OF CANCER
Revisión2021 Leptin, both bad and good actor in cancer BIOMOLECULES
Revisión2021 Nutritional modulation of leptin expression and leptin action in obesity and obesity-associated complications JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Revisión2021 Stem cells and COVID-19: are the human amniotic cells a new hope for therapies against the SARS-CoV-2 virus? Stem cell research & therapy
Artículo2020 Crosstalk between estradiol and NFκB signaling pathways on placental leptin expression Reproduction (Cambridge, England)
Artículo2020 Development and validation of a laboratory-based risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19 Scandinavian Journal of Clinical and Laboratory Investigation
Resumen congreso2020 Evolution of cytotoxic and regulatory T cells in blood and in tissue after neoadjuvant treatment in breast carcinoma ANNALS OF ONCOLOGY
Resumen congreso2020 Implantación de la tromboelastometría en pacientes sometidos a cirugía cardiovascular REC: interventional cardiology
Artículo2020 Leptin and nutrition in gestational diabetes NUTRIENTS
Artículo2020 Postprandial triglyceride-rich lipoproteins promote M1/M2 microglia polarization in a fatty-acid-dependent manner JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Revisión2020 Role of leptin in inflammation and vice versa INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2020 Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS ENDOCRINE CONNECTIONS
Capítulo2019 Aquaporins and placenta Vitamins and Hormones
Artículo2019 Automated urinalysis combining physicochemical analysis, on-board centrifugation, and digital imaging in one system: A multicenter performance evaluation of the cobas 6500 urine work area Practical Laboratory Medicine
Resumen congreso2019 Evolution of myeloid-derived suppressor cells and objective response rate in relapsed/refractory diffuse large B cell lymphoma (R/R DLBCL) patients after receiving immunotherapy ANNALS OF ONCOLOGY
Resumen congreso2019 Evolution of the myeloid-derived suppressor cells in advanced breast cancer and comparative analysis with a healthy population cohort JOURNAL OF CLINICAL ONCOLOGY
Artículo2019 First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus PLOS ONE
Artículo2019 Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cells SCIENTIFIC REPORTS
Artículo2019 Leptin protects placental cells from apoptosis induced by acidic stress CELL AND TISSUE RESEARCH
Artículo2019 Leptin stimulates DMP-1 and DSPP expression in human dental pulp via MAPK 1/3 and PI3K signaling pathways ARCHIVES OF ORAL BIOLOGY
Resumen congreso2019 Myeloid derived-suppressor cells in healthy women and in advanced breast cancer patients ANNALS OF ONCOLOGY
Revisión2019 New horizons in breast cancer: the promise of immunotherapy CLINICAL & TRANSLATIONAL ONCOLOGY
Ponencia2019 Role of leptin on the apoptosis of trophoblast explants triggered by acidosis PLACENTA
Artículo2019 Sam68 media la señal y la acción de la leptina en granulosa humana: posible papel en la resistencia a la leptina en PCOS Endocrinologia, Diabetes y Nutricion
Artículo2019 Screening for Gestational Diabetes Mellitus by Measuring Glycated Hemoglobin Can Reduce the Use of the Glucose Challenge Test ANNALS OF LABORATORY MEDICINE
Artículo2018 Diabetes mellitus and cardiovascular risk: Update of the recommendations of the Diabetes and Cardiovascular Disease working group of the Spanish Diabetes Society (SED, 2018) CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS
Artículo2018 Fasting Glycemia as Screening Tool to Rule-Out Gestational Diabetes in Low-Risk Population CLINICAL LABORATORY
Revisión2018 Involvement of leptin in the molecular physiology of the placenta REPRODUCTION
Revisión2018 Leptin action in normal and pathological pregnancies JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Artículo2018 Leptin upregulates aquaporin 9 expression in human placenta in vitro GYNECOLOGICAL ENDOCRINOLOGY
Artículo2018 Placental leptin expression is mediated by NFκB signaling PLACENTA
Artículo2018 Proliferation and survival of human amniotic epithelial cells during their hepatic differentiation PLOS ONE
Resumen congreso2017 Amniotic membrane conditioned medium promotes cell death and inhibits proliferation of hepatocarcinoma HepG2 cells PLACENTA
Revisión2017 Breast Cancer Immunology and Immunotherapy: Current Status and Future Perspectives INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 331
Artículo2017 Comparison of Citrate Buffer with Sodium Fluoride as Additives in Determining Glycemia CLINICAL LABORATORY
Revisión2017 Role of leptin as a link between metabolism and the immune system CYTOKINE & GROWTH FACTOR REVIEWS
Artículo2017 Sp1 transcription factor is a modulator of estradiol leptin induction in placental cells PLACENTA
Artículo2016 Diabetes mellitus and cardiovascular risk: Working group recommendations of Diabetes and Cardiovascular Disease of the Spanish Society of Diabetes (SED, 2015) ATENCION PRIMARIA
Artículo2016 Increased Expression of Aquaporin 9 in Trophoblast From Gestational Diabetic Patients HORMONE AND METABOLIC RESEARCH
Artículo2016 Insulin and Leptin Signaling in Placenta from Gestational Diabetic Subjects HORMONE AND METABOLIC RESEARCH
Artículo2016 Leptin reduces apoptosis triggered by high temperature in human placental villous explants: The role of the p53 pathway PLACENTA
Capítulo2016 Pancreastatin signaling. mechanisms of action The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Capítulo2016 Pancreastatin, a regulatory peptide derived from chromogranin A The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Artículo2016 Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells PLOS ONE
Ponencia2015 Antiapoptotic effects of leptin on trophoblasts PLACENTA
Artículo2015 Demostración experimental de la presencia de leptina y su receptor en pulpa dental y tejido periapical humanos Gaceta Dental
Artículo2015 Diabetes mellitus y riesgo cardiovascular: recomendaciones del Grupo de Trabajo Diabetes y Enfermedad Cardiovascular de la Sociedad Española de Diabetes (SED, 2015) CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS
Artículo2015 Evaluation of a HbA1c point-of-care analyzer CLINICAL BIOCHEMISTRY
Artículo2015 Expression and immunohistochemical localization of leptin in human periapical granulomas Medicina oral, patología oral y cirugía bucal
Artículo2015 Expression and immunohistochemical localization of leptin receptor in human periapical granuloma INTERNATIONAL ENDODONTIC JOURNAL
Ponencia2015 Human amniotic epithelial cells: Proliferation and apoptosis during their hepatic differentiation PLACENTA
Capítulo2015 La leptina, adipokinas, obesidad, resistencia a la insulina y más allá Actualizaciones en bioquímica clínica
Ponencia2015 Leptin is involved in human trophoblast migration and invasion PLACENTA
Artículo2015 Leptin Promotes Dentin Sialophosphoprotein Expression in Human Dental Pulp JOURNAL OF ENDODONTICS
Artículo2015 Leptin promotes HLA-G expression on placental trophoblasts via the MEK/Erk and PI3K signaling pathways PLACENTA
Artículo2015 Mechanisms involved in p53 downregulation by leptin in trophoblastic cells PLACENTA
Revisión2015 Role of leptin in female reproduction CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2014 GSK3 beta is increased in adipose tissue and skeletal muscle from women with gestational diabetes where it regulates the inflammatory response PLOS ONE
Artículo2014 Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells PLOS ONE
Artículo2014 Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation PLOS ONE
Resumen congreso2014 Pathological complete response and changes related to t infiltrating lymphocytes and regulatory t cells in tissue and peripheral blood after neoadjuvant chemotherapy in breast carcinoma ANNALS OF ONCOLOGY
Artículo2014 Reference intervals for N-terminal pro-B-type natriuretic peptide in amniotic fluid between 10 and 34 weeks of gestation PLOS ONE
Artículo2014 Study of lymphocyte subpopulations and intrathecal secretion in patients with definite multiple sclerosis Acta Bioquimica Clinica Latinoamericana
Artículo2013 Activated Translation Signaling in Placenta from Pregnant Women with Gestational Diabetes Mellitus: Possible Role of Leptin HORMONE AND METABOLIC RESEARCH
Artículo2013 Effective treatment of pulmonary tuberculosis restores plasma leptin levels EUROPEAN CYTOKINE NETWORK
Artículo2013 Insulin enhances leptin expression in human trophoblastic cells BIOLOGY OF REPRODUCTION
Capítulo2013 Leptin action and leptin receptor signaling in human trophoblasts The Placenta: Development, Function and Diseases
Artículo2013 Leptin expression in healthy and inflamed human dental pulp INTERNATIONAL ENDODONTIC JOURNAL
Artículo2013 Leptin Receptor Is Up-regulated in Inflamed Human Dental Pulp JOURNAL OF ENDODONTICS
Revisión2013 New Insights into the Role of the Immune Microenvironment in Breast Carcinoma CLINICAL & DEVELOPMENTAL IMMUNOLOGY
Revisión2013 Role of Sam68 in post-transcriptional gene regulation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2012 Elsevier Trophoblast Research Award Lecture: Molecular mechanisms underlying estrogen functions in trophoblastic cells - Focus on leptin expression PLACENTA
Artículo2012 Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Artículo2012 Sam68 interacts with IRS1 BIOCHEMICAL PHARMACOLOGY
Artículo2012 The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells PLOS ONE
Artículo2011 Evaluation of two HbA1c point-of-care analyzers CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2011 Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells MOLECULAR AND CELLULAR ENDOCRINOLOGY
Artículo2011 Review: Leptin gene expression in the placenta - Regulation of a key hormone in trophoblast proliferation and survival PLACENTA
Capítulo2011 Role of leptin in the activation of the immune system Leptin: Hormonal Functions, Dysfunctions and Clinical Uses
Artículo2011 Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells HUMAN REPRODUCTION
Artículo2010 17Beta-Estradiol Enhances Leptin Expression in Human Placental Cells Through Genomic and Nongenomic Actions BIOLOGY OF REPRODUCTION
Artículo2010 Blocking of melatonin synthesis and MT1 receptor impairs the activation of Jurkat T cells CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2010 Glycated hemoglobin vs. the oral glucose tolerance test for the exclusion of impaired glucose tolerance in high-risk individuals CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2010 MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Revisión2010 Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin REGULATORY PEPTIDES
Artículo2010 Regulation of Placental Leptin Expression by Cyclic Adenosine 5 '-Monophosphate Involves Cross Talk between Protein Kinase A and Mitogen-Activated Protein Kinase Signaling Pathways Endocrinology
Revisión2010 Reprint of: Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin REGULATORY PEPTIDES
Revisión2010 Role of Leptin in the Activation of Immune Cells MEDIATORS OF INFLAMMATION
Ponencia2009 Haemoglobin A1c: Comparison of three point of care analysers with the central laboratory assay CLINICAL CHEMISTRY
Ponencia2009 Improvement of glycemic control of diabetic patients from primary care by an educational intervention together with an on-line quality control system from the central laboratory of Clinical Biochemistry CLINICAL CHEMISTRY
Artículo2009 Leptin Stimulates Protein Synthesis-Activating Translation Machinery in Human Trophoblastic Cells BIOLOGY OF REPRODUCTION
Artículo2009 Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Artículo2009 Up-Regulation of Placental Leptin by Human Chorionic Gonadotropin Endocrinology
Artículo2008 Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Artículo2008 Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Artículo2008 Profile of patients triply infected with HIV and the hepatitis B and C viruses in the HAART era AIDS RESEARCH AND HUMAN RETROVIRUSES
Artículo2008 Resultados de la implantación de un sistema de control de calidad para los glucómetros del Área Hospitalaria Virgen Macarena, con conexión on-line al Laboratorio de Bioquímica Clínica, durante el período 2003–2007, Revista del laboratorio clínico
Revisión2008 Role of leptin in the immune system Current Immunology Reviews
Artículo2007 Leptin promotes cell proliferation and survival of trophoblastic cells BIOLOGY OF REPRODUCTION
Ponencia2006 Bed-side glucose monitoring in a Health Area comprising 2 hospitals and 3 specialized health centers achieve recomended analytical goals after educative intervention and implantation of an on-line quality control system CLINICAL CHEMISTRY
Artículo2006 Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children METABOLISM-CLINICAL AND EXPERIMENTAL
Revisión2006 Leptin and the immune system Revista Española de Obesidad
Revisión2006 Signalling mechanisms regulating lipolysis CELLULAR SIGNALLING
Artículo2005 Daño vascular en la insuficiencia renal crónica. El aumento de depósitos vasculares de nitrotirosina y citocinas se acompaña de una elevación de la expresión vascular de la óxido nítrico sintasa endotelial (eNOS) NEFROLOGIA
Artículo2005 Educational intervention together with an on-line quality control program achieve recommended analytical goals for bedside blood glucose monitoring in a 1200-bed university hospital. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2005 eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells REGULATORY PEPTIDES
Artículo2005 Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation Journal of Molecular Endocrinology
Artículo2005 Oleylethanolamide impairs glucose tolerance and inhibits insulin-stimulated glucose uptake in rat adipocytes through p38 and JNK MAPK pathways AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Artículo2005 Pancreastatin: multiple actions on human intermediary metabolism in vivo, variation in disease, and naturally occurring functional genetic polymorphism JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Revisión2005 Role of Sam68 as an adaptor protein in signal transduction CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2005 Sam68 is tyrosine phosphorylated and recruited to signalling in peripheral blood mononuclear cells from HIV infected patients CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Ponencia2004 An on-line quality control system for the portable glucose meters in a 1200 bed university hospital CLINICAL CHEMISTRY
Artículo2004 Expresión vascular de la óxido nitrico sintasa endotelial (eNOS) en la hipertensión arterial esencial NEFROLOGIA
Artículo2004 Expression of activation molecules in neutrophils, monocytes and lymphocytes from patients with unstable angina treated with stent implantation CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2004 Marcadores biológicos de inflamación vascular y aterosclerosis subclínica en el síndrome metabólico MEDICINA CLINICA
Revisión2004 Pancreastatin, a regulatory peptide that modulates energy metabolism Current Medicinal Chemistry: Immunology, Endocrine and Metabolic Agents
Artículo2003 Leptin stimulates the oxidative burst in control monocytes but attenuates the oxidative burst in monocytes from HIV-infected patients CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Artículo2003 Pancreastatin, a chromogranin A-derived peptide, inhibits leptin and enhances UCP-2 expression in isolated rat adipocytes CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2003 Purification of pancreastatin receptor from rat liver membranes HOST-PATHOGEN INTERACTIONS: METHODS AND PROTOCOLS
Revisión2003 Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Artículo2003 The expression of Sam68, a protein involved in insulin signal transduction, is enhanced by insulin stimulation CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo2002 Elevated plasma total homocysteine levels in hyperinsulinemic obese subjects JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2002 Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway Cellular Immunology
Artículo2002 Inflammatory response to coronary stent implantation in patients with unstable angina CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Artículo2002 Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Artículo2002 Pancreastatin, a chromogranin A-derived peptide, activates protein synthesis signaling cascade in rat adipocytes BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Artículo2002 Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling JOURNAL OF CELLULAR BIOCHEMISTRY
Artículo2001 Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect Journal of Molecular Endocrinology
Artículo2001 Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: Possible role of Sam68 Cellular Immunology
Artículo2001 Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway Cellular Immunology
Artículo2001 Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTC rat hepatoma cells JOURNAL OF HEPATOLOGY
Artículo2001 Pancreastatin, a chromogranin-A-derived peptide, inhibits insulin-stimulated glycogen synthesis by activating GSK-3 in rat adipocytes BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Artículo2001 Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling MOLECULAR AND CELLULAR ENDOCRINOLOGY
Artículo2000 Affinity purification of pancreastatin receptor-Gq/11 protein complex from rat liver membranes ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Artículo2000 Characterization of pancreastatin receptor and signaling in rat HTC hepatoma cells EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2000 Human leptin enhances activation and proliferation of human circulating T lymphocytes Cellular Immunology
Artículo2000 Pancreastatin modulates insulin signaling in rat adipocytes: mechanisms of cross-talk DIABETES
Artículo2000 Pancreastatin: biological effects and mechanisms of action Advances in Experimental Medicine and Biology
Artículo2000 Stimulation of glycogen synthesis by insulin requires S6 kinase and phosphatidylinositol-3-kinase in HTC-IR cells JOURNAL OF CELLULAR PHYSIOLOGY
Ponencia1999 Analytical endogenous interferences on the Glucocard meter Glucocard Memory 2 CLINICAL CHEMISTRY
Artículo1999 Characterization of pancreastatin receptors and signaling in adipocyte membranes BIOCHIMICA ET BIOPHYSICA ACTA
Corrección1999 Erratum: Increased plasma pancreastatin-like levels in gestational diabetes (Diabetes Care (1998) 21 (1951-1954)) DIABETES CARE
Artículo1999 G protein Gα(q/11) and Gα(i1,2) are activated by pancreastatin receptors in rat liver: Studies with GTP-γ35S and azido-GTP-α-32P JOURNAL OF CELLULAR BIOCHEMISTRY
Artículo1999 Human leptin stimulates proliferation and activation of human circulating monocytes Cellular Immunology
Corrección1999 Increased plasma pancreastatin-like levels in gestational diabetes. (vol 21, pg 1951, 1998) DIABETES CARE
Artículo1999 Insulin activates G alpha(il,2) protein in rat hepatoma (HTC) cell membranes CELLULAR AND MOLECULAR LIFE SCIENCES
Artículo1999 Modulation of insulin receptor signalling by pancreastatin in HTC hepatoma cells DIABETOLOGIA
Artículo1999 p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K FEBS LETTERS
Artículo1998 Guanosine triphosphatase-activating protein-associated protein, but not src-associated protein p68 in mitosis, is a part of insulin signaling complexes Endocrinology
Artículo1998 Increased plasma pancreastatin-like levels in gestational diabetes - Correlation with catecholamine levels DIABETES CARE
Artículo1998 Pancreastatin activates beta 3 isoform of phospholipase C via G alpha(11) protein stimulation in rat liver membranes MOLECULAR AND CELLULAR ENDOCRINOLOGY
Artículo1998 Pancreastatin inhibits insulin action in rat adipocytes AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Artículo1998 Pancreastatin receptor is coupled to a guanosine triphosphate-binding protein of the G(q/11)alpha family in rat liver membranes HEPATOLOGY
Artículo1997 Melatonin Enhances IL-2, IL-6, and IFN-γ Production by Human Circulating CD4+ Cells: A Possible Nuclear Receptor-Mediated Mechanism Involving T Helper Type 1 Lymphocytes and Monocytes JOURNAL OF IMMUNOLOGY
Artículo1997 Normal pancreastatin-like and increased post-glucose insulin levels in young offspring of insulin-resistant non-obese essential hypertensive patients JOURNAL OF ENDOCRINOLOGY
Ponencia1997 Pancreastatin signaling in the liver NEUROCHEMISTRY
Artículo1997 Solubilization and molecular characterization of active pancreastatin receptors from rat liver membranes Endocrinology
Artículo1996 P-62: Role of phosphatidylinositol-3-kinase and S6 kinase in insulin-stimulated glycogen synthesis Experimental and Clinical Endocrinology and Diabetes
Artículo1996 Role of p85 isoforms of phosphatidylinositol-3-kinase in insulin receptor signaling Experimental and Clinical Endocrinology and Diabetes
Artículo1995 A CHEMILUMINESCENCE METHOD TO ANALYZE PHOSPHATIDYLCHOLINE-PHOSPHOLIPASE ACTIVITY IN PLASMA-MEMBRANE PREPARATIONS AND IN INTACT-CELLS ANALYTICAL BIOCHEMISTRY
Artículo1995 Increased plasma pancreastatin-like immunoreactivity levels in non-obese patients with essential hypertension JOURNAL OF HYPERTENSION
Artículo1995 Insulin-like growth factor-1 stimulation of cells induces formation of complexes containing phosphatidylinositol-3-kinase, guanosine triphosphatase-activating protein (GAP), and p62 GAP-associated protein Endocrinology
Artículo1995 Insulin-like growth-factor-i stimulation of cells induces formation of complexes containing phosphatidylinositol-3-kinase, guanosine triphosphatase-activating protein (gap), and p62 gap-associated protein Endocrinology
Revisión1995 PROTEIN-KINASE-C INVOLVEMENT IN APOPTOSIS GENERAL PHARMACOLOGY
Artículo1995 Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1 MOLECULAR ENDOCRINOLOGY
Artículo1994 Diminished insulin-receptors on erythrocyte-ghosts in nonobese patients with essential-hypertension independent of hyperinsulinemia JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Artículo1994 Pancreastatin activates pertussis-toxin-sensitive guanylate-cyclase and pertussis toxin-insensitive phospholipase-C in rat-liver membranes JOURNAL OF CELLULAR BIOCHEMISTRY
Artículo1994 PROTEIN-KINASE-C ACTIVATION PROMOTES CELL-SURVIVAL IN MATURE LYMPHOCYTES PRONE TO APOPTOSIS BIOCHEMICAL PHARMACOLOGY
Artículo1994 Receptors for pancreastatin in rat liver membranes: Molecular identification and characterization by covalent cross-linking MOLECULAR PHARMACOLOGY
Artículo1994 Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62, and GTPase-activating protein JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo1994 Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Artículo1993 PANCREASTATIN (33-49) ENHANCES THE PRIMING EFFECT OF GLUCOSE IN THE RAT PANCREAS EXPERIENTIA
Artículo1993 PANCREASTATIN DECREASES PLASMA EPINEPHRINE LEVELS IN SURGICAL STRESS IN THE RAT PEPTIDES
Artículo1993 PANCREASTATIN INCREASES FREE CYTOSOLIC CA2+ IN RAT HEPATOCYTES, INVOLVING BOTH PERTUSSIS-TOXIN-SENSITIVE AND PERTUSSIS-TOXIN-INSENSITIVE MECHANISMS BIOCHEMICAL JOURNAL
Nota1993 SENSITIVITY OF INSULIN-SECRETING RIN-M5F CELLS TO UNDERGOING APOPTOSIS BY THE PROTEIN-KINASE-C INHIBITOR STAUROSPORINE EXPERIMENTAL CELL RESEARCH
Nota1992 DECREASED PROTEIN-KINASE-C ACTIVITY IS ASSOCIATED WITH PROGRAMMED CELL-DEATH (APOPTOSIS) IN FRESHLY ISOLATED RAT HEPATOCYTES BIOSCIENCE REPORTS
Artículo1992 GLYCOGENOLYTIC EFFECT OF PANCREASTATIN IN ISOLATED RAT HEPATOCYTES IS MEDIATED BY A CYCLIC-AMP-INDEPENDENT CA2+-DEPENDENT MECHANISM BIOCHEMICAL JOURNAL
Artículo1992 PANCREASTATIN INCREASES CYTOSOLIC CA2+ IN INSULIN SECRETING RINM5F CELLS MOLECULAR AND CELLULAR ENDOCRINOLOGY
Libro1992 Papel de la pancreastatina en la homeostasis de la glucosa Papel de la pancreastatina en la homeostasis de la glucosa
Artículo1991 GLYCOGENOLYTIC EFFECT OF VASOACTIVE-INTESTINAL-PEPTIDE IN THE RAT INVIVO EXPERIENTIA
Artículo1990 GLYCOGENOLYTIC EFFECT OF PANCREASTATIN IN THE RAT BIOSCIENCE REPORTS

Tesis dirigidas/tutorizadas:25
Fecha lectura Título Rol
07/05/2021 IMPLICACIÓN DEL LABORATORIO CLÍNICO EN LA DETECCIÓN PRECOZ DE DISLIPEMIAS GENÉTICAS EN ATENCIÓN PRIMARIA Tutor/a
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13/07/2020 ESTUDIO POBLACIONES CELULARES EN PACIENTES CON LINFOMA DIFUSO DE CÉLULAS B GRANDES REFRACTARIOS O EN RECAÍDA: PAPEL DE LAS CÉLULAS SUPRESORAS DE ORIGEN MIELOIDE EN RESPUESTA AL TRATAMIENTO R2-GDP Director/a, Tutor/a
06/02/2020 EFECTO PROTECTOR DEL ACEITE DE OLIVA SOBRE LA ACTIVACIÓN DE LA MICROGLÍA Tutor/a
15/01/2020 DETERMINACIÓN DE LOS PERFILES DE SENSIBILIZACIÓN POLÍNICA Y RELEVANCIA CLÍNICA DE LOS ALÉRGENOS DE ALIMENTOS EN PACIENTES POLÍNICOS SENSIBILIZADOS A PROFILINA Tutor/a
21/09/2018 ESTUDIO DEL PROCESO DE MODIFICACIÓN POSTRADUCCIONAL DE PROTEÍNAS POR UNIÓN DEL POLIPÉPTIDO SUMO EN CONDICIONES SIMULADAS DE ISQUEMIA Tutor/a
18/07/2018 CÁLCULO DE UN ÍNDICE DE RIESGO DE PADECER DIABETES GESTACIONAL PARA SU USO COMO CRIBADO UNIVERSAL Tutor/a, Director/a
19/06/2018 PREVALENCIA DEL DÉFICIT DE VITAMINA D Y SIGNIFICADO PRONÓSTICO EN PACIENTES ANCIANOS INGRESADOS POR SÍNDROME CORONARIO AGUDO Director/a, Tutor/a
12/03/2018 EVALUACIÓN DE LOS RESULTADOS EN SALUD TRAS LA IMPLEMENTACIÓN DE LA TROMBOELASTOMETRÍA ROTACIONAL EN PACIENTES SOMETIDOS A CIRUGÍA CARDIOVASCULAR CON CRICULACIÓN EXTRACORPÓREA Tutor/a, Director/a
26/01/2018 UTILIDAD DE LAS CADENAS LIGERAS LIBRES EN LÍQUIDO CEFALORRAQUÍDEO COMO BIOMARCADOR DE CONVERSIÓN A ESCLEROSIS MÚLTIPLE CLÍNICAMENTE DEFINIDA Tutor/a
23/10/2017 CONTRIBUCIÓN DE UN DESAYUNO DE TIPO MEDITERRÁNEO A LA PREVENCIÓN DEL DESARROLLO DE ATEROSCLEROSIS EN INDIVIDUOS OBESOS. Tutor/a
22/09/2017 PAPEL DE SAM68 EN LA DIFERENCIACIÓN DEL ADIPOCITO Director/a
24/09/2014 LEPTINA Y SU RECEPTOR EN TEJIDO DENTAL HUMANO SANO E INFLAMADO Director/a
10/07/2013 ESTUDIO DE LAS BASES GENÉTICAS DE ENFERMEDADES DEL NEURODESARROLLO: EPILEPSIA Y AUTISMO Tutor/a
08/11/2012 ESTUDIO CITOGENÉTICO DE LOS SINDROMES MIELODISPLASICOS EN EL AREA HOSPITALARIA VIRGEN MACARENA: PAPEL PRONÓSTICO DE LA MUTACIÓN TP53 EN LOS SINDROMES MIELODISPLASICOS Director/a
24/05/2012 ENFERMEDAD DE POMPE: PROTOCOLO DIAGNÓSTICO POR EL LABORATORIO CLÍNICO Tutor/a
17/10/2011 EVALUACIÓN E IMPLEMENTACIÓN DE UN SISTEMA POCT DE HBA1C CONTROLADO POR EL LABORATORIO PARA GARANTIZAR LA CALIDAD ANALÍTICA Director/a
07/06/2010 PAPEL DE SAM68 EN LA SEÑAL DEL RECEPTOR DE LEPTINA EN CÉLULAS DE PLACENTA Director/a
28/06/2007 ACCIÓN Y MECANISMO DE ACCIÓN DE LA LEPTINA HUMANA EN LA PLACENTA Director/a
04/07/2006 MECANISMOS DE INMUNOMODULACIÓN DE LA LEPTINA EN CÉLULAS T JURKAT Director/a
13/06/2006 LEPTINA. ESTUDIO SOBRE ESTRÉS OXIDATIVO Y LA VÍA DE SEÑALIZACIÓN CELULAR EN MONOCITOS DE PACIENTES VIH POSITIVOS Director/a
25/06/2004 PAPEL DE SAM 68 EN LA SEÑALIZACIÓN DEL RECEPTOR DE INSULINA Director/a
11/07/2003 Efecto de la pancreastatina en el tejido adiposo Director/a
06/06/2002 ACCIÓN Y MECANISMO DE ACCIÓN DE LA LEPTINA HUMANA EN SISTEMA INMUNE Director/a
28/01/1999 CARACTERIZACIÓN FUNCIONAL Y MOLECULAR DE RECEPTOR DE PANCREASIATINA EN MEMBRANAS HEPÁTICAS DE RETA Director/a

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2020 31/12/2022 Investigador/a Deciphering the role of dietary fatty acids on HDL functionality (P18-RT-3324) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)
01/03/2006 30/12/2009 Investigador/a La hemoglobina glicosilada en el diagnóstico de la intolerancia a la glucosa (prediabetes) y el riesgo cardiovascular (EXC/2005/CTS-572) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico)
05/05/2011 31/12/2014 Responsable Investigación sobre nuevos marcadores de valoración embrionaria (IPT-2011-1488-900000) Ministerio de Ciencia e Innovación (Nacional)
01/02/2020 31/01/2022 Investigador/a Descifrando el papel de los ácidos grasos de la dieta sobre la funcionalidad de las HDL (US-1263458) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2011 31/12/2011 Responsable Estudio de niveles de leptina y morfología dinámica preembionaria preimplantacional. (1068/0450) IVI Sevilla, S.L. (Local)