José Manuel Rodríguez Martínez

Profesor Titular de Universidad
jmrodriguez@us.es
Área de conocimiento: Microbiología
Departamento: Microbiología
Grupo: RESISTENCIA A ANTIMICROBIANOS (CTS-210)
Instituto de Inv.: IBIS
Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)
Tipo Año Título Fuente
Artículo2021 Activity of fosfomycin and amikacin against fosfomycin-heteroresistant Escherichia coli strains in a hollow-fiber infection model ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2021 Clinical characteristics and outcome of bacteraemia caused by Enterobacter cloacae and Klebsiella aerogenes: more similarities than differences JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
Artículo2021 Disbalancing Envelope Stress Responses as a Strategy for Sensitization of Escherichia coli to Antimicrobial Agents FRONTIERS IN MICROBIOLOGY
Artículo2021 Effect of RecA inactivation on quinolone susceptibility and the evolution of resistance in clinical isolates of Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2021 Interplay among different fosfomycin resistance mechanisms in klebsiella pneumoniae ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2021 Synergistic quinolone sensitization by targeting the recA SOS response gene and oxidative stress ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2020 Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Nota2020 Detection of low-level fosfomycin-resistant variants by decreasing glucose-6-phosphate concentration in fosfomycin susceptibility determination Antibiotics
Artículo2020 Role of low-level quinolone resistance in generating tolerance in Escherichia coli under therapeutic concentrations of ciprofloxacin JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2019 A prospective, multicenter case control study of risk factors for acquisition and mortality in Enterobacter species bacteremia JOURNAL OF INFECTION
Artículo2019 Association of blaOXA-1, and aac(6′)-Ib-cr with ST405 K. pneumoniae clone ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2019 Suppression of the SOS response modifies spatiotemporal evolution, post-antibiotic effect, bacterial fitness and biofilm formation in quinolone-resistant Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2018 Prevalence of ST131 Clone Producing Both ESBL CTX-M-15 and AAC(6)Ib-cr Among Ciprofloxacin-Resistant Escherichia coli Isolates from Yemen MICROBIAL DRUG RESISTANCE
Artículo2018 Urinary Tract Conditions Affect Fosfomycin Activity against Escherichia coli Strains Harboring Chromosomal Mutations Involved in Fosfomycin Uptake ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2017 Cellular Response to Ciprofloxacin in Low-Level Quinolone-Resistant Escherichia coli FRONTIERS IN MICROBIOLOGY
Artículo2017 Characterization of Plasmid-Mediated Quinolone Resistance Determinants in High-Level Quinolone-Resistant Enterobacteriaceae Isolates from the Community: First Report of qnrD Gene in Algeria MICROBIAL DRUG RESISTANCE
Artículo2017 Cytotoxic Effect Associated with Overexpression of QNR Proteins in Escherichia coli MICROBIAL DRUG RESISTANCE
Artículo2017 Molecular Characterization of Fluoroquinolone-Resistant Haemophilus parainfluenzae Clinical Isolates in Spain MICROBIAL DRUG RESISTANCE
Artículo2017 Molecular insights into fosfomycin resistance in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2017 Molecular topology: A new strategy for antimicrobial resistance control EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2017 Occurrence of the Plasmid-Mediated Fluoroquinolone Resistance qepA1 Gene in Two Clonal Clinical Isolates of CTX-M-15-Producing Escherichia coli from Algeria MICROBIAL DRUG RESISTANCE
Revisión2017 Plasmid-mediated quinolone resistance in Enterobacteriaceae: a systematic review with a focus on Mediterranean countries EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Artículo2017 Plasmidic qnr Genes Confer Clinical Resistance to Ciprofloxacin under Urinary Tract Physiological Conditions ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2017 Quinolone Resistance Reversion by Targeting the SOS Response MBIO
Artículo2017 Rapid detection of the plasmid-mediated quinolone resistance determinant AAC(6 ')-Ib-cr in Enterobacteriaceae by MALDI-TOF MS analysis JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2017 Role of inoculum and mutant frequency on fosfomycin MIC discrepancies by agar dilution and broth microdilution methods in Enterobacteriaceae CLINICAL MICROBIOLOGY AND INFECTION
Letter2016 Assessment of a phenotypic algorithm to detect plasmid-mediated quinolone resistance in Enterobacteriaceae JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2016 Assessment of Chromosomal DNA Fragmentation by Quinolones in an Isogenic Collection of Escherichia coli with Defined Resistance Mechanisms MICROBIAL DRUG RESISTANCE
Artículo2016 Comparison of clinical categories for Escherichia coli harboring specific qnr and chromosomal-mediated fluoroquinolone resistance determinants according to CLSI and EUCAST ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Letter2016 First report of the plasmid-mediated colistin resistance gene mcr-1 in a clinical Escherichia coli isolate in Algeria INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2016 Impact of AAC(6 ')-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Revisión2016 Plasmid-mediated quinolone resistance: Two decades on DRUG RESISTANCE UPDATES
Artículo2016 Reduced Susceptibility to Cefepime in Clinical Isolates of Enterobacteriaceae Producing OXA-1 Beta-Lactamase MICROBIAL DRUG RESISTANCE
Artículo2016 Urinary Tract Physiological Conditions Promote Ciprofloxacin Resistance in Low-Level-Quinolone-Resistant Escherichia coli ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2015 Challenges to accurate susceptibility testing and interpretation of quinolone resistance in Enterobacteriaceae: results of a Spanish multicentre study JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2015 Effect of the efflux pump QepA2 combined with chromosomally mediated mechanisms on quinolone resistance and bacterial fitness in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2015 Pharmacodynamics of Fosfomycin: Insights into Clinical Use for Antimicrobial Resistance ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2014 Interplay between plasmid-mediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2014 Lactococcus garvieae carries a chromosomally encoded pentapeptide repeat protein that confers reduced susceptibility to quinolones in Escherichia coli producing a cytotoxic effect Research in Microbiology
Artículo2014 Presence of quinolone resistance to qnrB1 genes and bla(OXA-48) carbapenemase in clinical isolates of Klebsiella pneumoniae in Spain ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2013 Contribution of OqxAB efflux pumps to quinolone resistance in extended-spectrum--lactamase-producing Klebsiella pneumoniae JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Letter2013 High level of fluoroquinolone resistance in a respiratory isolate of Haemophilus parainfluenzae associated with a new mutation in ParC ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2013 Impact of qnrA1, qnrB1 and qnrS1 on the efficacy of ciprofloxacin and levofloxacin in an experimental pneumonia model caused by Escherichia coli with or without the GyrA mutation Ser83Leu JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Capítulo2013 Plasmid-mediated quinolone resistance Microbial drug resistance
Letter2012 Ausencia del sistema de expulsión de quinolonas mediado por plásmido QacBIII en aislados bacteriémicos de staphylococcus aureus en el área hospitalaria Virgen Macarena de Sevilla ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2012 Combination of bla(VIM-1) and qnrS2 on the same plasmid in Klebsiella oxytoca and Klebsiella pneumoniae isolates in Seville ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2012 Exposure to diverse antimicrobials induces the expression of qnrB1, qnrD and smaqnr genes by SOS-dependent regulation JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2012 Genetic characterization of an extended-spectrum AmpC cephalosporinase with hydrolysing activity against fourth-generation cephalosporins in a clinical isolate of Enterobacter aerogenes selected in vivo JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2012 Group IIC Intron with an Unusual Target of Integration in Enterobacter cloacae JOURNAL OF BACTERIOLOGY
Artículo2012 Prevalence of plasmid-mediated quinolone resistance determinants qnr and aac(6 ')-Ib-cr in Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases in Spain INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Letter2012 Production of a plasmid-encoded OXA-72 beta-lactamase associated with resistance to carbapenems in a clinical isolate Acinetobacter junii INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Letter2011 Discrepancies in fluoroquinolone clinical categories between the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and CLSI for Escherichia coli harbouring qnr genes and mutations in gyrA and parC JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2011 Evaluation of Three Automated Systems for Susceptibility Testing of Enterobacteria Containing qnrB, qnrS, and/or aac(6 ')-Ib-cr JOURNAL OF CLINICAL MICROBIOLOGY
Artículo2011 In Vitro Effect of qnrA1, qnrB1, and qnrS1 Genes on Fluoroquinolone Activity against Isogenic Escherichia coli Isolates with Mutations in gyrA and parC ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Editorial2011 Local imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Letter2011 Molecular characterization of high-level fluoroquinolone resistance in a clinical isolate of Haemophilus parainfluenzae JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Revisión2011 Plasmid-mediated quinolone resistance: an update JOURNAL OF INFECTION AND CHEMOTHERAPY
Póster2010 ADDITIVE EFFECT OF QNR GENES, SER83LEU SUBSTITUTION IN DNA GYRASE AND SER80ARG IN TOPOISOMERASE IV ON THE FLUOROQUINOLONE RESISTANCE IN E. COLI CLINICAL MICROBIOLOGY AND INFECTION
Artículo2010 Characterization of DIM-1, an Integron-Encoded Metallo-beta-Lactamase from a Pseudomonas stutzeri Clinical Isolate in the Netherlands ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Letter2010 Characterization of fluoroquinolone resistance in a clinical isolate of Pseudomonas stutzeri JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Ponencia2010 EFECTO DE QNRA, QNRB Y QNRS EN LA ACTIVIDAD IN VIVO DE FLUOROQUINOLONAS EN CEPAS DE ESCHERICHIA COLI CON MUTACIÓN EN GYRA ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Póster2010 EFFECT OF QNRA, QNRB AND QNRS ON THE IN VIVO ACTIVITY OF FLUOROQUINOLONES CLINICAL MICROBIOLOGY AND INFECTION
Artículo2010 Extended-Spectrum Cephalosporinase in Acinetobacter baumannii ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2010 Genetic and functional variability of AmpC-type â-lactamases from Acinetobacter baumannii ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Ponencia2010 PREVALENCIA DE LOS GENES QNRA, QNRB, QNRS Y AAC-IB-CR EN ENTEROBACTERIAS PRODUCTORAS DE BETALACTAMASAS DE ESPECTRO EXTENDIDO (BLEE) EN ESPAÑA ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2010 Smaqnr, a new chromosome-encoded quinolone resistance determinant in Serratia marcescens JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2010 VIM-19, a Metallo-beta-Lactamase with Increased Carbapenemase Activity from Escherichia coli and Klebsiella pneumoniae ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Ponencia2009 AMPC CEFALOSPORINASAS CON ESPECTRO DE HIDRÓLISIS EXTENDIDO HACIA CEFEPIME Y CARBAPENEMAS EN PSEUDOMONAS AERUGINOSA ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2009 CARACTERIZACIÓN DE BLADIM-1, UNA NUEVA BETALACTAMASA DE CLASE B LOCALIZADA EN UN INTEGRÓN DE CLASE 1 EN UN AISLADO CLÍNICO MULTIRRESISTENTE DE PSEUDOMONAS STITZERI ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2009 CHARACTERISATION OF BLADIM-1, A NOVEL INTEGRON-LOCATED METALLO-BETA-LACTAMASE GENE FROM A PSEUDOMONAS STUTZERI CLINICAL ISOLATE IN THE NETHERLANDS CLINICAL MICROBIOLOGY AND INFECTION
Artículo2009 Detection of Plasmid-Mediated Quinolone Resistance Genes in Clinical Isolates of Enterobacter spp. in Spain JOURNAL OF CLINICAL MICROBIOLOGY
Letter2009 ENDOGENOUS CEPHALOSPORINASES IN P. AERUGINOSA MAY CONFER CARBAPENEM RESISTANCE JOURNAL HIGHLIGHTS (MICROBE)
Artículo2009 Extended-Spectrum Cephalosporinases in Pseudomonas aeruginosa ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2009 Long-term control of hospital-wide, endemic multidrug-resistant Acinetobacter baumannii through a comprehensive "bundle'' approach American Journal of Infection Control
Artículo2009 Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Pseudomonas aeruginosa ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Ponencia2009 MOLECULAR EPIDEMIOLOGY AND MECHANISMS OF CARBAPENEM RESISTANCE IN PSEUDOMONAS AERUGINOSA ISOLATES FROM A FRENCH HOSPITAL CLINICAL MICROBIOLOGY AND INFECTION
Artículo2009 Mutational analysis of quinolone resistance in the plasmid-encoded pentapeptide repeat proteins QnrA, QnrB and QnrS JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2009 Naturally Occurring Class A beta-Lactamases from the Burkholderia cepacia Complex ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Póster2009 SERRATIA MARCESCENS CARRIES A CHROMOSOMALLY ENCODED PENTAPEPTIDE REPEAT PROTEIN, CONFERRING REDUCED SUSCEPTIBILITY TO QUINOLONES IN E. COLI CLINICAL MICROBIOLOGY AND INFECTION
Artículo2008 Activity of ciprofloxacin and levofloxacin in experimental pneumonia caused by Klebsiella pneumoniae deficient in porins, expressing active efflux and producing QnrA1 CLINICAL MICROBIOLOGY AND INFECTION
Artículo2008 Antimicrobial activity in bacterial biofilms ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Letter2008 Ceftazidime-resistant Klebsiella oxytoca producing an OXY-2-type variant from Switzerland INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Ponencia2008 EVOLUTION OF QUINOLONE RESISTANCE MEDIATED BY GENETIC CHANGES IN QNRA, QNRB AND QNRS GENES CLINICAL MICROBIOLOGY AND INFECTION
Artículo2008 Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC Mutation JOURNAL OF CLINICAL MICROBIOLOGY
Revisión2008 Plasmid-mediated quinolone resistance EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
Artículo2008 Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants BMC MICROBIOLOGY
Ponencia2008 PREVALENCIA DE LOS GENES QNRA, QNRB Y QNRS, Y AAC(6¿)IB-CR EN ESCHERICHIA COLI PRODUCTOR DE BETA-LACTAMASAS DE ESPECTRO EXTENDIDO AISLADOS DE ALIMENTOS, PORTADORES SANOS, INFECCIONES URINARIAS Y BACTERIEMIAS ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2008 Qnr-like pentapeptide repeat proteins in Gram-positive bacteria JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2007 Actividad y permeabilidad de linezolid y vancomicina en biocapas de Staphylococcus epidermidis ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Letter2007 Activity and penetration of fosfomycin, ciprofloxacin, amoxicillin/clavulanic acid and co-trimoxazole in Escherichia coli and Pseudomonas aeruginosa biofilms INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2007 Characterisation of integrons containing the plasmid-mediated quinolone resistance gene qnrA1 in Klebsiella pneumoniae INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2007 Mutant prevention concentrations of fluoroquinolones for Enterobacteriaceae expressing the plasmid-carried quinolone resistance determinant qnrA1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Ponencia2007 PENETRATION AND ACTIVITY OF FOSFOMYCIN, CIPROflOXACIN, AMOXICILLIN PLUS CLAVULANIC ACID AND COTRIMOXAZOL IN ESCHERICHIA COLI AND PSEUDOMONAS AERUGINOSA BIOfiLMS CLINICAL MICROBIOLOGY AND INFECTION
Ponencia2007 Role of the pentapeptidic proteins from Gram-positive bacteria as a possible source of Qnr-like quinolone resistance determinants INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Ponencia2006 ACTIVIDAD DE IMIPENEM EN LA PERITONITIS EXPERIMENTAL POR CUERPO EXTRAÑO (LÁTEX SILICONIZADO VS. SILICONA) CAUSADA POR PSEUDOMONAS AERUGINOSA. ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2006 Antimicrobial resistance in bacterial biofilms Reviews in Medical Microbiology
Letter2006 Characterization of a clinical isolate of Haemophilus influenzae with a high level of fluoroquinolone resistance JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2006 Common region CR1 for expression of antibiotic resistance genes ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2006 Correlation of quinolone resistance levels and differences in basal and quinolone-induced expression from three qnrA-containing plasmids CLINICAL MICROBIOLOGY AND INFECTION
Ponencia2006 DETECCIÓN DEL GEN DE RESISTENCIA PLASMÍDICA A QUINOLONAS QNR EN CEPAS DE ESCHERICHIA COLI Y KLEBSIELLA PNEUMONIAE PRODUCTORAS DE BETALACTAMASAS DE ESPECTRO EXTENDIDO (BLEE) PERTENECIENTES AL ESTUDIO MULTICÉNTRICO GEIH-BLEE 2000. ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2006 DETECTION OF QNRS IN CLINICAL ISOLATES OF ENTEROBACTER CLOACAE IN SPAIN. CLINICAL MICROBIOLOGY AND INFECTION
Artículo2006 In vivo selection of Enterobacter aerogenes with reduced susceptibility to cefepime and carbapenems associated with decreased expression of a 40 kDa outer membrane protein and hyperproduction of AmpC beta-lactamase INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Artículo2006 In vivo selection of fluoroquinolone-resistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum beta-lactamase ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Ponencia2006 PENETRATION AND ACTIVITY OF LINEZOLID AND VANCOMYCIN IN S. EPIDERMIDIS BIOFILMS CLINICAL MICROBIOLOGY AND INFECTION
Artículo2006 Plasmid-mediated quinolone resistance in Australia MICROBIAL DRUG RESISTANCE
Letter2006 Resistance to imipenem and zinc in clinical isolates of Pseudomonas aeruginosa INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Letter2006 Survival and resistance to imipenem of Pseudomonas aeruginosa on latex gloves JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2005 Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 beta-lactamase ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2005 Evaluation of antimicrobial susceptibility of bacteria containing the qnr gene and FOX-5 beta-lactamase by four automated systems CLINICAL MICROBIOLOGY AND INFECTION
Ponencia2005 FACTORS AFFECTING RESISTANCE TO QUINOLONES MEDIATED BY PLASMIDS CONTAINING THE QNRA GENE. CLINICAL MICROBIOLOGY AND INFECTION
Revisión2005 MECANISMOS DE RESISTENCIA A QUINOLONAS MEDIADA POR PLÁSMIDOS ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Artículo2005 Origin of plasmid-mediated quinolone resistance determinant QNRA ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Artículo2005 Transient rebounds of hiv plasma vieremia are associated with the emergence of drug resistance mutations in patients on highly active antiretroviral therapy JOURNAL OF INFECTION
Artículo2005 Vibrionaceae as a possible source of Qnr-like quinolone resistance determinants JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Ponencia2004 CARACTERIZACIÓN DE HAEMOPHILUS INFLUENZAE CON RESISTENCIA DE ALTO NIVEL A FLUORQUINOLONAS ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2004 EFFICACY OF CEFEPIME AND IMIPENEM IN EXPERIMENTAL PNEUMONIA CAUSED BY PORIN-DEFICIENT KLEBSIELLA PNEUMONIAE PRODUCIN CMY-2 LACTAMASE CLINICAL MICROBIOLOGY AND INFECTION
Ponencia2004 FREQUENCY AND STABILITY OF MUTANTS SELECT WITH FLUOROQUINOLONES FROM KLEBSIELLA PNEUMONIAE CONTAINING THE PLASMID-MEDIATED RESISTANCE DETERMINANT QNR CLINICAL MICROBIOLOGY AND INFECTION
Ponencia2004 IN VIVO SELECTION OF ENTEROBACTER AEROGENES WITH REDUCED SUSCEPTIBILITY TO CEFEPIME ASSOCIATED WITH EITHER DECREASED EXPRESSION OF AN OUTER MEMBRANE PTOTEIN OF 40 KDA OR HYPERPRODUCTION OF AMPC BETA-LACTAMASE CLINICAL MICROBIOLOGY AND INFECTION
Artículo2004 Resistencia genotípica del virus de la inmunodeficiencia humana tipo 1 en pacientes con fracaso terapéutico MEDICINA CLINICA
Ponencia2003 BACTERICIDAL ACTIVITY OF FLUOROQUINOLONES AGAINST KLEBSIELLA PNEUMONIAE CONTAINING THE PLASMID-MEDIATED RESISTANCE DETERMINANT QNR CLINICAL MICROBIOLOGY AND INFECTION
Artículo2003 Detection of the plasmid-mediated quinolone resistance determinant qnr among clinical isolates of Klebsiella pneumoniae producing AmpC-type beta-lactamase JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Artículo2003 Study of different systems for interpreting results of genotypic antiretroviral drug resistance tests ANTIVIRAL THERAPY
Ponencia2002 EVALUACIÓN DE DIFERENTES BASES DE DATOS DE RESISTENCIA A ANTIRRETROVIRALES DE VIH ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2002 EVALUACIÓN DE LAS RESISTENCIAS A ANTIRRETROVIRALES DE VIH EN PACIENTES MULTITRATADOS ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2002 FRECUENCIA DEL DETERMINANTE DE RESISTENCIA A QUINOLONAS QNR EN CEPAS CLÍNICAS DE ESCHERICHIA COLI Y KLEBSIELLA PNEUMONIAE ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Ponencia2002 SUBTIPOS DE VIH DETECTADOS EN PACIENTES ESTUDIADOS EN EL ÁREA HOSPITALARIA DE SEVILLA ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
17/03/2008 30/06/2011 Investigador/a Prevalencia, Caracterización Funcional y Relevancia Clínica de la Resistencia a Quinolonas Mediada por Proteínas Pentapeptídicas en Enterobacterias y Bacterias Gram-Positivas. (P07-CTS-02908) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/01/2012 31/12/2014 Responsable Interacción de mecanismos plasmídicos y cromosómicos de resistencia a quinolonas en escherichia coli y su efecto en la resistencia, fitness, toxicidad celular y expresión en biocapas (PI11/00934) Ministerio de Ciencia e Innovación (Instituto de Carlos III) (Nacional)
26/03/2013 31/12/2016 Investigador/a Análisis de la Interacción de los Mecanismos Plasmídicos y Cromosómicos de Resistencia a Quinolonas: Efecto Sobre la Selección de Resistencias, Fitness Bacteriano, Toxicidad Celular y Niveles de Expresión en Biocapas Bacterianas (P11-CTS-7730) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/01/2015 30/06/2018 Responsable Potenciación de la respuesta ROS e inhibición del sistema SOS como adyuvantes del tratamiento antimicrobiano para la sensibilización de bacterias Gram-negativas resistentes (PI14/00940) FEDER - Ministerio de Economía y Competitividad (Instituto de Salud Carlos III) (Nacional)
01/01/2021 31/12/2023 Responsable Procesos moleculares implicados en heteroresistance y tolerancia: estrategias de diagnóstico y eficacia antimicrobiana en clones multirresistentes de Enterobacterales. (Proyecto Tolerancia-Cero) (PI20/00239) Ministerio de Ciencia e Innovación (Instituto de Salud Carlos III) (Nacional)
15/11/2003 15/11/2006 Investigador/a Regulación y evaluación in vivo de la resistencia de Pseudomonas aeruginosa a antimicrobianos inducida por el cinc liberado de sondas urinarias (SAF2003-01241) Ministerio de Ciencia y Tecnología (Nacional)