Nuria Pastor Carrillo

Profesora Titular de Universidad
npastor@us.es
Área de conocimiento: Biología Celular
Departamento: Biología Celular
Grupo: CULTIVO CELULAR Y RADIOBIOLOGIA (BIO-120)
Tipo Año Título Fuente
Artículo2021 Biocompatible DNA/5-fluorouracil-gemini surfactant-functionalized gold nanoparticles as promising vectors in lung cancer therapy PHARMACEUTICS
Revisión2021 The Role of DNA Damage Response in Dysbiosis-Induced Colorectal Cancer Cells
Artículo2018 Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside DRUG DEVELOPMENT RESEARCH
Artículo2018 The Cockayne syndrome protein B is involved in the repair of 5-AZA-2'-deoxycytidine-induced DNA lesions ONCOTARGET
Artículo2017 Educación científica en la universidad: semejanzas y diferencias entre futuros maestros y biólogos acerca de la naturaleza de la ciencia ENSENANZA DE LAS CIENCIAS
Artículo2017 RENEB intercomparison exercises analyzing micronuclei (Cytokinesis-block Micronucleus Assay) INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Artículo2017 Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination DNA REPAIR
Artículo2014 The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2 '-deoxycytidine lesions NUCLEIC ACIDS RESEARCH
Artículo2013 5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair NUCLEIC ACIDS RESEARCH
Artículo2013 Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death TOXICOLOGY LETTERS
Artículo2012 Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death PHARMACOLOGICAL REPORTS
Artículo2012 The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I- and II-DNA Complexes in Cells JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2012 The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication Mutation Research
Ponencia2011 Complementos de aprendizaje en la asignatura de cultivos celulares: la conferencia a distancia mediante wimba classroom y la conferencia presencial [Póster] IX Jornades de xarxes d'investigació en docència universitària: Disseny de bones pràctiques docents en el context actual
Ponencia2010 On the mechanism of demethylating agents-induced DNA damage TOXICOLOGY LETTERS
Ponencia2010 The methylating agent budesonide protects from m-AMSA induced endoreduplication and DNA damage in the repair deficient CHO mutant EM9 TOXICOLOGY LETTERS
Artículo2010 The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II Mutation Research
Artículo2009 Cytotoxicity and mitotic alterations induced by non-genotoxic lithium salts in CHO cells in vitro TOXICOLOGY IN VITRO
Artículo2008 Tea flavanols inhibit cell growth and DNA topoisomerase II activity and induce endoreduplication in cultured Chinese hamster cells MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2008 The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA Mutation Research
Revisión2007 Topoisomerase inhibitors as therapeutic weapons EXPERT OPINION ON THERAPEUTIC PATENTS
Artículo2006 Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II Mutation Research
Artículo2006 Digitoxin, at concentrations commonly found in the plasma of cardiac patients, antagonizes etoposide and idarubicin activity in K562 leukemia cells LEUKEMIA RESEARCH
Artículo2006 Evaluation of genotoxic effects of heavy metals and arsenic in wild nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from southwestern Spain after a mining accident Environmental Toxicology And Chemistry
Artículo2006 Halogen substitution of DNA protects from poisoning of topoisomerase II that results in DNA double-strand breaks DNA REPAIR
Artículo2006 Modulation of radiation response by inhibiting topoisomerase II catalytic activity Mutation Research
Artículo2005 Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients JOURNAL OF NATURAL PRODUCTS
Artículo2005 Endoreduplication induced in cultured Chinese hamster cells by different anti-topoisomerase II chemicals - Evidence for the essential contribution of the enzyme to chromosome segregation MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2005 Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2005 The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells Mutation Research
Artículo2004 A 4 year follow-up analysis of genotoxic damage in birds of the Donana area (south west Spain) in the wake of the 1998 mining waste spill MUTAGENESIS
Revisión2004 Toward a comprehensive model for induced endoreduplication LIFE SCIENCES
Artículo2003 Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii PLANTA MEDICA
Artículo2003 Bufalin influences the repair of X-ray-induced DNA breaks in Chinese hamster cells DNA REPAIR
Artículo2003 DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193 Mutation Research
Revisión2003 Induction of endoreduplication by topoisomerase II catalytic inhibitors MUTAGENESIS
Revisión2003 Roles of DNA topoisomerases in chromosome segregation and mitosis MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
Artículo2003 The nature of DNA plays a role in chromosome segregation: endoreduplication in halogen-substituted chromosomes DNA REPAIR
Artículo2002 A comparative study of genotoxic effects of anti-topoisomerase II drugs ICRF-193 and bufalin in Chinese hamster ovary cells MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2002 DNA topoisomerase activities in Chinese hamster radiosensitive mutants after X-ray treatment CELL BIOLOGY INTERNATIONAL
Artículo2002 High yield of endoreduplication induced by ICRF-193: a topoisomerase II catalytic inhibitor MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2001 Assessment of genotoxic damage by the comet assay in white storks (Ciconia ciconia) after the Donana Ecological Disaster MUTAGENESIS
Artículo2001 DNA damage in birds after the mining waste spill in southwestern Spain: A comet assay evaluation Journal of Environmental Pathology, Toxicology and Oncology
Artículo2001 DNA topoisomerases in cancer chemotherapy: basic and applied aspects CYTOBIOS
Letter2001 Ionizing radiation damage repair: a role for topoisomerases? MUTAGENESIS
Artículo2001 Testing the SCE mechanism with non-poisoning topoisomerase II inhibitors MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo1999 Topoisomerase activities and levels in irradiated Chinese hamster AA8 cells and in its radiosensitive mutant EM9 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Artículo1996 Bovine and rabbit lymphocytes conditioned with hydrogen peroxide show an adaptive response to radiation damage Mutation Research

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
30/01/2014 31/07/2018 Investigador/a Interés de los Polifenoles en Inflamación Crónica y Cáncer: Papel en los Sistemas Celulares de Regulación Mitocondrial y del Inflamasoma. Polfanat-II (P12-AGR-430) Consejería de Economía, Innovación y Ciencia (Autonómico)
01/10/2007 04/10/2010 Investigador/a Estudio y valoración del papel que desempeñan las enzimas nucleares topoisomerasas de ADN en los procesos de inestabilidad genómica (BFU2007-61301) Ministerio de Educación y Ciencia (Nacional)
13/12/2004 13/12/2007 Investigador/a Importancia de la enzima nuclear topoisomerasa II de ADN en la segregación coromosómica: efecto de la sustitución del ADN y la inhibición catalítica de la enzima (BFU2004-00884) Ministerio de Ciencia y Tecnología (Nacional)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
07/02/2001 07/06/2001 Investigador/a Estudio ictiológico de los embalses de Arrocampo y Torrejón (OG-084/01) A.I.E. Centrales Nucleares (Nacional)
31/12/2020 31/12/2022 Responsable Importancia de MYCN en la sensibilidad en células madre de neuroblastoma a inhibidores de MTH1 (4045/1078) NEN - Asociación de familias y amigos de pacientes enfermos de neuroblastoma (Nacional)
01/01/1999 31/12/2000 Investigador/a ESTUDIO ICTIOLÓGICO DE LOS EMBALSES DE ARROCAMPO Y TORREJÓN (OG-078/00)
01/07/2016 31/12/2017 Investigador/a Evaluación preclinica de nuevas estrategias anticancerosas orientadas al paciente oncológico (2812/0836) Asociación para el Desarrollo de la Oncología (ADEON) (Local)
01/06/2015 31/05/2018 Investigador/a Characterization of the clastogenic effects, SCE and micronuclei in neuroblastoma stem cells after MTH 1 inhibitors and combinations (2594/0594) THE HELLEDAY FOUNDATION (Internacional)
01/10/2012 01/10/2013 Investigador/a "On the mechanism of demethylating agents-induced DNA damege". (1674/0594) Instituto Karolinska (Europeo)