Piedad del Socorro Murdoch

Profesora Titular de Universidad
socorro@us.es
Área de conocimiento: Bioquímica y Biología Molecular
Departamento: Bioquímica Vegetal y Biología Molecular
Grupo: Grupo de Metabolismo y Señalización Celular (BIO-356)
Tipo Año Título Fuente
Artículo2021 Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia Molecular Oncology
Artículo2017 The Sinorhizobium (Ensifer) fredii HH103 rkp-2 region is involved in the biosynthesis of lipopolysaccharide and exopolysaccharide but not in K-antigen polysaccharide production PLANT AND SOIL
Artículo2016 Exopolysaccharide Production by Sinorhizobium fredii HH103 Is Repressed by Genistein in a NodD1-Dependent Manner PLOS ONE
Artículo2016 The Sinorhizobium fredii HH103 MucR1 Global Regulator Is Connected With the nod Regulon and Is Required for Efficient Symbiosis With Lotus burttii and Glycine max cv. Williams MOLECULAR PLANT-MICROBE INTERACTIONS
Artículo2014 Developmental Defects in a Caenorhabditis elegans Model for Type III Galactosemia GENETICS
Artículo2012 Sinorhizobium fredii HH103 rkp-3 Genes Are Required for K-Antigen Polysaccharide Biosynthesis, Affect Lipopolysaccharide Structure and Are Essential for Infection of Legumes Forming Determinate Nodules MOLECULAR PLANT-MICROBE INTERACTIONS
Artículo2010 The rkpU gene of Sinorhizobium fredii HH103 is required for bacterial K-antigen polysaccharide production and for efficient nodulation with soybean but not with cowpea MICROBIOLOGY-SGM
Artículo2009 Identification by NMR Spectroscopy of the Two Stereoisomers of the Platinum Complex [PtCl2(S-ahaz)] (S-ahaz=3(S)-Aminohexahydroazepine) Bound to a DNA 14-mer Oligonucleotide. NMR Evidence of Structural Alteration of a Platinated A.T-rich 14-mer DNA Duplex INORGANIC CHEMISTRY
Artículo2009 Sinorhizobium fredii HH103 cgs Mutants Are Unable to Nodulate Determinate-and Indeterminate Nodule-Forming Legumes and Overproduce an Altered EPS MOLECULAR PLANT-MICROBE INTERACTIONS
Artículo2006 Reactions of Pt-II diamine anticancer complexes with trypanothione and octreotide JOURNAL OF INORGANIC BIOCHEMISTRY
Artículo2005 Laser flash-induced kinetic analysis of cytochrome f oxidation by wild-type and mutant plastocyanin from the cyanobacterium Nostoc sp PCC 7119 BIOCHEMISTRY
Artículo2003 Novel adducts of the anticancer drug oxaliplatin with glutathione and redox reactions with glutathione disulfide EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
Artículo2002 An evolutionary analysis of the reaction mechanisms of photosystem I reduction by cytochrome c(6) and plastocyanin BIOELECTROCHEMISTRY
Artículo2002 Five-coordinate aminophosphine platinum(II) complexes containing cysteine derivatives as ligands INORGANICA CHIMICA ACTA
Artículo2002 Reactions of a ruthenium(II) arene antitumor complex with cysteine and methionine INORGANIC CHEMISTRY
Artículo2001 [H-1, N-15] NMR studies of the platination of phosphorothioate nucleotides - Monofunctional sulfur adducts versus macrochelation EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
Ponencia2001 An evolutionary approach to the structure and function of photosynthetic metalloproteins JOURNAL OF INORGANIC BIOCHEMISTRY
Artículo2001 Inhibition of cancer cell growth by ruthenium(II) arene complexes JOURNAL OF MEDICINAL CHEMISTRY
Artículo2000 Sequence-dependent bending of DNA induced by cisplatin: NMR structures of an A center dot T-rich 14-mer duplex CHEMISTRY-A EUROPEAN JOURNAL
Artículo1999 A novel dinuclear diaminoplatinum(II) glutathione macrochelate ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Artículo1999 Kinetics of formation and stability of {Pt(dien)}2+ complexes with octamer and 14-mer DNA oligonucleotides containing a GG sequence Journal of Biological Inorganic Chemistry
Artículo1999 Surprising reactions of iodo Pt(IV) and Pt(II) complexes with human albumin: Detection of Cys34 sulfenic acid JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Artículo1998 Electron-transfer-driven trans-ligand labilization: A novel activation mechanism for Pt(IV) anticancer complexes JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Artículo1998 Interconversion between S- and N-bound L-methionine adducts of pt(dien)(2+) (dien = diethylenetriamine) via dien ring-opened intermediates JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS
Artículo1997 Chelate-ring-opened adducts of [Pt(en)(Me-Mal-O,O')] (en equals ethane-1,2-diamine, Me-Mal equals 2-methylmalonate) with methionine derivatives: Relevance to the biological activity of platinum anticancer agents Journal of the Chemical Society. Dalton Transactions
Artículo1997 Platination of a GG site on single-stranded and double-stranded forms of a 14-base oligonucleotide with diaqua cisplatin followed by NMR and HPLC - Influence of the platinum ligands and base sequence on 5'-G versus 3'-G platination selectivity European Journal of Biochemistry
Artículo1996 Ring-opened adducts of the anticancer drug carboplatin with sulfur amino acids INORGANIC CHEMISTRY
Artículo1995 L-methionine increases the rate of reaction of 5'-guanosine monophosphate with the anticancer drug cisplatin - mixed-ligand adducts and reversible methionine binding JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS
Nota1994 [Pt(CBDCA-O)(NH3)2(L-Methionine-S)]: Ring-Opened Adduct of the Anticancer Drug Carboplatin (“Paraplatin”). Detection of a Similar Complex in Urine by NMR Spectroscopy JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Artículo1994 Intermolecular displacement of s-bound l-methionine on platinum(ii) by guanosine 5'-monophosphate - implications for the mechanism of action of anticancer drugs JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Artículo1993 Cis-Trans Isomerization of [Pt(l-methionine)2]: Metabolite of the Anticancer Drug Cisplatin INORGANIC CHEMISTRY
Este investigador no ha dirigido/tutorizado tesis

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/10/2006 30/09/2009 Investigador/a Análisis evolutivo y relación estructura-función del citocromo c y su equivalente metabólico, el citocromo c6, como inductores de muerte celular programada (BFU2006-01361) Ministerio de Educación y Ciencia (Nacional)
30/12/2016 29/12/2019 Investigador/a El Regulón Simbiótico de Sinorhizobium Fredii: Identificación de Genes Clave en la Interacción Simbiótica con Soja y en la Leguminosa Modelo Lotus. (BIO2016-78409-R) Ministerio de Economía y Competitividad (Nacional)
15/11/2003 15/11/2006 Investigador/a Relación estructura-función e interacciones entre metaloproteínas (BMC2003-00458) Ministerio de Ciencia y Tecnología (Nacional)
26/03/2013 30/09/2016 Investigador/a Estudios de las Simbiosis Establecidas por Sinorhizobium Fredii con la Soja y la Leguminosa Modelo Lotus (P11-CVI-7500) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
20/12/2000 20/12/2003 Investigador/a Reconocimiento molecular e ingeniería de proteínas fotosintéticas (BMC2000-0444) Ministerio de Ciencia y Tecnología (Nacional)
01/01/2012 30/06/2015 Investigador/a Señales de Sinorhizobium Fredii que Participan en su Interacción Simbiótica con las Leguminosas. (BIO2011-30229-C02-01) Ministerio de Ciencia e Innovación (Nacional)