Manuel de Miguel Rodríguez

Catedrático de Universidad
mmiguel@us.es
Área de conocimiento: Histología
Departamento: Citología e Histología Normal y Patológ.
Grupo: BIOPATOLOGÍA Y ESTRÉS OXIDATIVO (CTS-949)
Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)
Tipo Año Título Fuente
Artículo2021 Dietary alpha- and gamma-tocopherol (1:5 ratio) supplementation attenuates adipose tissue expansion, hepatic steatosis, and expression of inflammatory markers in a high-fat-diet–fed murine model NUTRITION
Artículo2021 Native Chilean berries preservation and in vitro studies of a polyphenol highly antioxidant extract from maqui as a potential agent against inflammatory diseases ANTIOXIDANTS
Artículo2020 Mitochondrial imbalance as a new approach to the study of fibromyalgia Open Access Rheumatology: Research and Reviews
Artículo2020 Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn's Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways NUTRIENTS
Artículo2020 Quantification of boron compound concentration for BNCT using positron emission tomography Cells
Artículo2019 Autohemotherapy with ozone as a possible effective treatment for Fibromyalgia Acta Reumatologica Portuguesa
Artículo2019 Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis Diseases
Editorial2018 Preclinical [F-18]tetrafluoroborate-PET/CT imaging of pituitary gland hyperplasia JAPANESE JOURNAL OF CLINICAL ONCOLOGY
Artículo2018 Role of dietary alpha- and gamma-tocopherol from Rosa mosqueta oil in the prevention of alterations induced by high-fat diet in a murine model NUTRITION
Artículo2017 Amitriptyline down-regulates coenzyme Q(10) biosynthesis in lung cancer cells EUROPEAN JOURNAL OF PHARMACOLOGY
Revisión2017 Fibromyalgia syndrome and temporomandibular disorders with muscular pain. A review MODERN RHEUMATOLOGY
Ponencia2017 Mitophagy activation in blood mononuclear cells as a possible biomarker for the diagnosis of fibromyalgia. HISTOLOGY AND HISTOPATHOLOGY
Artículo2016 Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells Genes & Cancer
Artículo2016 Targeted multifunctional tannic acid nanoparticles RSC ADVANCES
Ponencia2015 Extracting emergent knowledge about the socioeconomic urban contexts UbiComp and ISWC 2015 - Proceedings of the 2015 ACM International Joint Conference on Pervasive and Ubiquitous Computing and the Proceedings of the 2015 ACM International Symposium on Wearable Computers
Artículo2015 Leptin Promotes Dentin Sialophosphoprotein Expression in Human Dental Pulp JOURNAL OF ENDODONTICS
Artículo2014 Clinical symptoms in fibromyalgia are associated to overweight and lipid profile RHEUMATOLOGY INTERNATIONAL
Artículo2014 Coenzyme Q(10) Therapy MOLECULAR SYNDROMOLOGY
Artículo2014 NLRP3 Inflammasome Is Activated in Fibromyalgia: The Effect of Coenzyme Q(10) ANTIOXIDANTS & REDOX SIGNALING
Artículo2014 NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder BRAIN BEHAVIOR AND IMMUNITY
Artículo2013 Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis CELL DEATH & DISEASE
Artículo2013 Can Coenzyme Q(10) Improve Clinical and Molecular Parameters in Fibromyalgia? ANTIOXIDANTS & REDOX SIGNALING
Artículo2013 Expression of hypothalamic regulatory peptides in thyroid C cells of different mammals GENERAL AND COMPARATIVE ENDOCRINOLOGY
Artículo2013 Head and neck cancer. an aetiopathogenetic study of non-endemic lymphoepithelioma ACTA OTORHINOLARYNGOLOGICA ITALICA
Artículo2013 Is Inflammation a Mitochondrial Dysfunction-Dependent Event in Fibromyalgia? ANTIOXIDANTS & REDOX SIGNALING
Ponencia2012 Antitumoral effect promoted by amitriptyline in combination with camptothecin in a breast cancer cell line FEBS JOURNAL
Artículo2012 Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation BMC MEDICINE
Ponencia2012 Characterization of Thyroid and Non-Thyroid Tumors with a Novel PET Tracer [18F]tetrafluoroborate in a Rat Model EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Artículo2012 Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells HISTOLOGY AND HISTOPATHOLOGY
Ponencia2012 Mitochondrial dysfunction and ROS induce inflammation in Fibromyalgia patients FEBS JOURNAL
Ponencia2012 Molecular imaging of experimental thyroid proliferative disorders FEBS JOURNAL
Artículo2012 Molecular Study of Signaling-Pathway Genes in Experimental Rat Thyroid Carcinoma ENDOCRINE RESEARCH
Artículo2012 Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient NUTRITION
Artículo2012 Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients JOURNAL OF PSYCHIATRIC RESEARCH
Artículo2012 Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia: Coenzyme Q(10) Effect on Clinical Improvement PLOS ONE
Artículo2012 Recovery of MERRF Fibroblasts and Cybrids Pathophysiology by Coenzyme Q(10) NEUROTHERAPEUTICS
Ponencia2012 ROS and antioxidant levels of normal and neoplasic thyroid cells are affected differently by amitryptiline in oxidative therapy FEBS JOURNAL
Artículo2012 Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease BRITISH JOURNAL OF PHARMACOLOGY
Ponencia2012 Screening of pharmacological treatments for MELAS syndrome using cellular models of the disease FEBS JOURNAL
Artículo2011 Amitriptyline induces coenzyme Q deficiency and oxidative damage in mouse lung and liver TOXICOLOGY LETTERS
Artículo2011 Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria APOPTOSIS
Artículo2011 Clinical symptoms in Fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma PLOS ONE
Artículo2011 Coenzyme Q(10): A novel therapeutic approach for Fibromyalgia? Case series with 5 patients MITOCHONDRION
Artículo2011 Ghrelin potentiates TSH-induced expression of the thyroid tissue-specific genes thyroglobulin, thyroperoxidase and sodium-iodine symporter, in rat PC-Cl3 Cells PEPTIDES
Artículo2011 Inmunohistochemical Profile of Solid Cell Nest of Thyroid Gland ENDOCRINE PATHOLOGY
Revisión2011 Mitochondrial dysfunction in fibromyalgia and its implication in the pathogenesis of disease MEDICINA CLINICA
Artículo2011 Molecular findings of nasopharyngeal carcinoma in a European population ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY
Artículo2011 Patentar contra el cáncer de pulmón en el contexto de la Ley antitabaco Agenda de la Empresa Andaluza
Artículo2011 Secondary coenzyme Q(10) deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts FASEB JOURNAL
Artículo2011 The cadherin-catenin complex in nasopharyngeal carcinoma EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
Letter2011 The Effect of Coenzyme Q(10) on Symptoms of Mother and Son with Fibromyalgia Syndrome JOURNAL OF MUSCULOSKELETAL PAIN
Artículo2010 Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs ANTI-CANCER DRUGS
Artículo2010 Low levels of serotonin in serum correlates with severity of fibromyalgia MEDICINA CLINICA
Artículo2010 Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease ARTHRITIS RESEARCH & THERAPY
Artículo2010 Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients CLINICAL BIOCHEMISTRY
Revisión2010 Oxidative stress and mitochondrial dysfunction in fibromyalgia NEUROENDOCRINOLOGY LETTERS
Artículo2010 Stress reduction at the cellular levels Fibromyalgia Aware
Artículo2009 C cells evolve at the same rhythm as follicular cells when thyroidal status changes in rats JOURNAL OF ANATOMY
Artículo2009 Coenzyme Q(10) and alpha-tocopherol protect against amitriptyline toxicity TOXICOLOGY AND APPLIED PHARMACOLOGY
Artículo2009 Coenzyme Q10 distribution in blood is altered in patients with Fibromyalgia CLINICAL BIOCHEMISTRY
Artículo2009 Functional expression of the thyrotropin receptor in C cells: new insights into their involvement in the hypothalamic-pituitary-thyroid axis JOURNAL OF ANATOMY
Artículo2008 Cytotoxic effects of amitriptyline in human fibroblasts TOXICOLOGY
Artículo2008 W43X SDHD mutation in sporadic head and neck paraganglioma ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY
Artículo2005 Thyrotropin-releasing hormone receptor expression in thyroid follicular cells: a new paracrine role of C-cells? HISTOLOGY AND HISTOPATHOLOGY
Artículo2004 Ki-ras mutational analysis in rat follicular-cell proliferative lesions of the thyroid gland induced by radioactive iodine and potassium perchlorate Journal of Endocrinological Investigation
Ponencia2003 Heterogeneity of DNA and proliferation markers is the hallmark of monoclonal adrenocortical neoplasms MODERN PATHOLOGY
Artículo2003 The Ret proto-oncogene in the WAG/Rij rat strain: an animal model for inherited C-cell carcinoma? LABORATORY ANIMALS
Ponencia2002 Are the intraepidermal high-grade melanocytic lesions the direct precursors of invasive malignant melanomas? JOURNAL OF PATHOLOGY
Ponencia2002 Cell kinetics contributions to the differential genetic pattern of C-cell and adrenal medullary hyperplasias in multiple endocrine neoplasia 2A JOURNAL OF PATHOLOGY
Artículo2002 Comparative immunohistochemical study of normal, hyperplastic and neoplastic C cells of the rat thyroid gland CELL AND TISSUE RESEARCH
Ponencia2002 Critical reappraisal of pathologic criteria for the diagnosis of adrenocortical proliferative lesions JOURNAL OF PATHOLOGY
Ponencia2002 Distinctive kinetic profile contributes to the differential genetic pattern of C-cell and adrenal medullary hyperplasias in multiple endocrine neoplasia 2A LABORATORY INVESTIGATION
Ponencia2002 Malignant pheochromocytomas are characterized by topographic genetic heterogeneity involving multiple tumor suppressor gene loci, suggesting multistep tumorigenesis LABORATORY INVESTIGATION
Ponencia2002 Regressive features define Spitz tumors as characterized by cell kinetics, cell cycle regulators, and microvessel density JOURNAL OF PATHOLOGY
Artículo2001 Contribution of the microvessel network to the clonal and kinetic profiles of adrenal cortical proliferative lesions Human Pathology
Ponencia2001 Divergent genetic evolution of C-cell and adrenal medullary hyperplasias in multiple endocrine neoplasia 2A LABORATORY INVESTIGATION
Artículo2001 Expression of galectins-1 and -3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritis JOURNAL OF RHEUMATOLOGY
Artículo2001 Expression of galectins-1 and-3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritis JOURNAL OF RHEUMATOLOGY
Artículo2001 Flow cytometry, DNA ploidy, Ki-67 label and overexpression of p53 protein in 121 T1 superficial bladder cancer. Retrospective study. 2nd Part: Prognostic value and utility in the selection of the tretment with prophylactic BCG ACTAS UROLOGICAS ESPANOLAS
Ponencia2001 Genetic evolution of neural crest derivatives in multiple endocrine neoplasia 2A. Differential patterns for C-cell and adrenal medullary hyperplasias JOURNAL OF PATHOLOGY
Ponencia2001 Genetic heterogeneity by topographic compartments in pheochromocytomas suggest a convergent cell selection in the peripheral area JOURNAL OF PATHOLOGY
Artículo2001 Germline RET 634 mutation positive MEN 2A-related C-cell hyperplasias have genetic features consistent with intraepithelial neoplasia JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Ponencia2001 Neoplastic progression in the adrenal cortex is better defined by DNA and proliferation heterogeneity JOURNAL OF PATHOLOGY
Artículo2001 Prognostic value of DNA flow cytometry in sympathoadrenal paragangliomas ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY
Artículo2000 cDNA sequence and genomic structure of the rat RET proto-oncogene DNA SEQUENCE
Ponencia2000 Clonal and kinetic profiles correlate with vascular patterns in adrenal cortical lesions. JOURNAL OF PATHOLOGY
Artículo2000 Clonal patterns in phaeochromocytomas and MEN-2A adrenal medullary hyperplasias: histological and kinetic correlates JOURNAL OF PATHOLOGY
Artículo2000 Clonality as expression of distinctive cell kinetics patterns in nodular hyperplasias and adenomas of the adrenal cortex AMERICAN JOURNAL OF PATHOLOGY
Ponencia2000 Concordant inactivated X-chromosome results from early monoclonal expansions of neural crest precursors in MEN-2A JOURNAL OF PATHOLOGY
Artículo2000 DNA ploidy determination with flow cytometry, Ki-67 index, and overexpression of p53 protein in 121 T1 superficial bladder carcinoma. Retrospective study. Correlation with classic variables ACTAS UROLOGICAS ESPANOLAS
Artículo2000 Kinetic profiles of intraepithelial and invasive prostatic neoplasias: the key role of down-regulated apoptosis in tumor progression VIRCHOWS ARCHIV
Ponencia1999 Clonality patterns are expression of kinetic features in adrenal cortical nodular hyperplasias and adenomas. LABORATORY INVESTIGATION
Ponencia1999 Clonality patterns in adrenal cortical nodular hyperplasias and adenomas are mainly determined by kinetic features. JOURNAL OF PATHOLOGY
Ponencia1999 Is cancer-associated prostatic intraepithelial neoplasia A precancerous lesion? LABORATORY INVESTIGATION
Ponencia1999 Is prostatic intraepithelial neoplasia always a precancerous lesion? JOURNAL OF PATHOLOGY
Artículo1999 Topoisomerase activities and levels in irradiated Chinese hamster AA8 cells and in its radiosensitive mutant EM9 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Artículo1998 Expresión del oncogén C-ERB-B2 en carcinomas tiroideos de origen folicular y parafolicular Patología
Ponencia1998 Spontaneous thyroid neoplasia in rats MODERN PATHOLOGY
Ponencia1997 Clonally heterogeneous proliferations in benign adrenal cortical lesions. LABORATORY INVESTIGATION
Ponencia1997 Distinctive clonal and histological patterns in locally invasive pheochromocytomas. LABORATORY INVESTIGATION
Ponencia1997 DNA deletions, apoptosis blockage and x-linked clonality analysis in MEN-2A related C-cell lesions LABORATORY INVESTIGATION
Ponencia1996 Diagnostic and prognostic parameters in adrenal cortical proliferative lesions: A critical review. LABORATORY INVESTIGATION
Ponencia1996 Mitotic index quantification: Different approaches and their value in adrenocortical proliferative lesions. LABORATORY INVESTIGATION
Artículo1996 Study of Histriculus cavicola cyst wall using different lectins ARCHIV FUR PROTISTENKUNDE
Artículo1996 Value of ploidy pattern and nuclear texture in the diagnosis of primary hyperparathyroidism ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY
Artículo1995 Grados histológicos del carcinoma de próstata mediante métodos cuantimétricos Patología
Ponencia1992 ANALYSIS OF HISTRICULUS CAVICOLA CYST WALL GLYCOCONJUGATES USING DIFFERENT LECTINS JOURNAL OF PROTOZOOLOGY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/12/2003 31/08/2008 Investigador/a Contribución de las células C en la regulación intratiroidea de las células foliculares (BFI2003-00606) Ministerio de Ciencia y Tecnología (Nacional)
13/01/2009 13/01/2012 Investigador/a Estudio del Papel Regulador de los Péptidos Orexigénicos y Anorexigénicos Producidos por las Células C a Nivel del Tiroides sobre la Síntesis de Hormonas Tiroideas (P08-CVI-03598) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
27/03/2010 26/03/2012 Responsable Estudio comparativo de los niveles de estrés oxidativo y antioxidantes en células sanas y neoplásicas. (0712/0342) Ferlab, S.L. (Local)