Santiago Mateos Cordero

Catedrático de Universidad
smateos@us.es
Área de conocimiento: Biología Celular
Departamento: Biología Celular
Grupo: CULTIVO CELULAR Y RADIOBIOLOGIA (BIO-120)
Tipo Año Título Fuente
Artículo2018 Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside DRUG DEVELOPMENT RESEARCH
Artículo2018 The Cockayne syndrome protein B is involved in the repair of 5-AZA-2'-deoxycytidine-induced DNA lesions ONCOTARGET
Artículo2017 Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans - joint RENEB and EURADOS inter-laboratory comparisons INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Artículo2017 Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination DNA REPAIR
Artículo2016 Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid TOXINS
Artículo2015 Effect of DNA repair deficiencies on the cytotoxicity of resveratrol WebmedCentral.com
Artículo2013 5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair NUCLEIC ACIDS RESEARCH
Artículo2013 A Hydroalcoholic Extract from the Leaves of Nerium oleander Inhibits Glycolysis and Induces Selective Killing of Lung Cancer Cells PLANTA MEDICA
Artículo2013 Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death TOXICOLOGY LETTERS
Artículo2013 Selective Cytotoxic Activity of New Lipophilic Hydroxytyrosol Alkyl Ether Derivatives JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2012 Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death PHARMACOLOGICAL REPORTS
Artículo2012 The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I- and II-DNA Complexes in Cells JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2012 The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication Mutation Research
Ponencia2010 On the mechanism of demethylating agents-induced DNA damage TOXICOLOGY LETTERS
Artículo2010 Realización de seminarios a distancia mediante el uso de herramientas de blackboard (wimbaclassroom de webct) para conocer las aplicaciones y avances de los cultivos celulares en relación al ámbito laboral REDU-REVISTA DE DOCENCIA UNIVERSITARIA
Ponencia2010 The methylating agent budesonide protects from m-AMSA induced endoreduplication and DNA damage in the repair deficient CHO mutant EM9 TOXICOLOGY LETTERS
Artículo2010 The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II Mutation Research
Artículo2009 Cytotoxicity and mitotic alterations induced by non-genotoxic lithium salts in CHO cells in vitro TOXICOLOGY IN VITRO
Artículo2009 DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin MUTAGENESIS
Artículo2009 The mycotoxin ochratoxin A inhibits DNA topoisomerase II and induces polyploidy in cultured CHO cells TOXICOLOGY IN VITRO
Artículo2008 Genotoxicity detected in wild mice living in a highly polluted wetland area in south western Spain ENVIRONMENTAL POLLUTION
Artículo2008 Protection of halogenated DNA from strand breakage and sister-chromatid exchange induced by the topoisomerase I inhibitor camptothecin Mutation Research
Artículo2008 The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA Mutation Research
Revisión2007 Topoisomerase inhibitors as therapeutic weapons EXPERT OPINION ON THERAPEUTIC PATENTS
Artículo2006 Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II Mutation Research
Artículo2006 Halogen substitution of DNA protects from poisoning of topoisomerase II that results in DNA double-strand breaks DNA REPAIR
Artículo2006 Modulation of radiation response by inhibiting topoisomerase II catalytic activity Mutation Research
Artículo2006 Topoisomerase II inhibition and high yield of endoreduplication induced by the flavonoids luteolin and quercetin MUTAGENESIS
Artículo2005 Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2005 The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells Mutation Research
Revisión2004 Toward a comprehensive model for induced endoreduplication LIFE SCIENCES
Artículo2003 DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193 Mutation Research
Revisión2003 Roles of DNA topoisomerases in chromosome segregation and mitosis MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
Artículo2003 The nature of DNA plays a role in chromosome segregation: endoreduplication in halogen-substituted chromosomes DNA REPAIR
Artículo2002 A comparative study of genotoxic effects of anti-topoisomerase II drugs ICRF-193 and bufalin in Chinese hamster ovary cells MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2002 High yield of endoreduplication induced by ICRF-193: a topoisomerase II catalytic inhibitor MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2001 Testing the SCE mechanism with non-poisoning topoisomerase II inhibitors MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Artículo2001 The use of DNA double-strand break quantification in radiotherapy International Journal of Radiation: Oncology - Biology - Physics
Capítulo2000 Seguimiento, vigilancia, control y remediación de la contaminación generada por el vertido minero de Aznalcóllar: Subproyecto 4.8: efectos biológicos del vertido de Aznalcóllar en el ratón moruno (Mus Spretus) de zonas afectadas del Río Guadiamar y Doñana Programa de Investigación del Corredor verde del Guadiamar PICOVER 1999-2002 : integrando investigación, conservación y desarrollo
Artículo2000 Variation in sensitizing effect of caffeine in human tumour cell lines after gamma-irradiation RADIOTHERAPY AND ONCOLOGY
Artículo2000 Yield of SCEs and translocations produced by 3 aminobenzamide in cultured Chinese hamster cells Mutation Research
Artículo1999 Increased levels of DNA topoisomerases in cultured CHO cells treated with the antitumour drug 5-azacytidine CYTOBIOS
Artículo1998 Differences between a human bladder carcinoma cell line and its radiosensitive clone in the formation of radiation-induced DNA double-strand breaks in different chromatin substrates Mutation research. DNA repair (Print)
Artículo1998 Enhanced sensitivity to topoisomerase inhibitors in synchronous CHO cells pre-treated with 5-azacytidine Mutation Research
Artículo1998 Study of DNA double-strand break induction in different chromatin substrates of radioresistant and radiosensitive human tumour cell lines BIOMEDICAL LETTERS
Artículo1996 Cell-cycle variation in DNA migration in pulsed-field gel electrophoresis INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Artículo1994 Dna double-strand break rejoining in xrs5 cells is more rapid in the g2 than in the g1 phase of the cell-cycle Mutation research. DNA repair (Print)
Artículo1993 Poly-d-lysine enhances the genotoxicity of bleomycin in cultured cho cells CARCINOGENESIS
Artículo1992 A comparative study of the potentiating effect of caffeine and poly-d-lysine on chromosome damage induced by X-rays in plant cells Mutation Research
Artículo1992 Mitomycin C, 4-nitroquinoline-1-oxide and ethyl methanesulfonate induced long-lived lesions in DNA which result in SCEs during successive cell cycles in human lymphocytes Mutation Research
Artículo1992 Poly-d-lysine in g(2) potentiates chromosome-damage induced by x-rays and mitomycin-c in cho cells Mutation Research
Artículo1991 Premature onset of mitosis and potentiation of chromosome-damage induced by poly-d-lysine in plant-cells - evidence for g2 repair Mutation Research
Artículo1990 Evidence for an adaptive response to radiation-damage in plant-cells conditioned with x-rays or incorporated tritium INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Artículo1989 G2 effects of dna-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin-c Mutation Research Letters
Nota1987 Acetaldehyde induces mature endoreduplicated allium-cepa root-cells to divide EXPERIENTIA
Artículo1987 Effects of caffeine and inhibitors of dna-synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells Mutation Research
Artículo1987 Factors affecting the production of sces by maleic hydrazide in root-tip chromosomes of allium cepa Mutation Research
Artículo1986 Cytotoxic and genotoxic effects of ethanol and acetaldehyde in root-meristem cells of Allium cepa Mutation Research
Artículo1985 C-mitosis, chromosomal-aberrations and sister chromatid exchanges induced by chloroform in root-tip cells of allium-cepa CYTOBIOS

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/10/2007 04/10/2010 Investigador/a Estudio y valoración del papel que desempeñan las enzimas nucleares topoisomerasas de ADN en los procesos de inestabilidad genómica (BFU2007-61301) Ministerio de Educación y Ciencia (Nacional)
13/12/2004 13/12/2007 Investigador/a Importancia de la enzima nuclear topoisomerasa II de ADN en la segregación coromosómica: efecto de la sustitución del ADN y la inhibición catalítica de la enzima (BFU2004-00884) Ministerio de Ciencia y Tecnología (Nacional)
30/01/2014 31/07/2018 Investigador/a Interés de los Polifenoles en Inflamación Crónica y Cáncer: Papel en los Sistemas Celulares de Regulación Mitocondrial y del Inflamasoma. Polfanat-II (P12-AGR-430) Consejería de Economía, Innovación y Ciencia (Autonómico)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/07/2016 31/12/2017 Investigador/a Evaluación preclinica de nuevas estrategias anticancerosas orientadas al paciente oncológico (2812/0836) Asociación para el Desarrollo de la Oncología (ADEON) (Local)
01/06/2015 31/05/2018 Investigador/a Characterization of the clastogenic effects, SCE and micronuclei in neuroblastoma stem cells after MTH 1 inhibitors and combinations (2594/0594) THE HELLEDAY FOUNDATION (Internacional)
01/10/2012 01/10/2013 Investigador/a "On the mechanism of demethylating agents-induced DNA damege". (1674/0594) Instituto Karolinska (Europeo)
31/12/2020 31/12/2022 Investigador/a Importancia de MYCN en la sensibilidad en células madre de neuroblastoma a inhibidores de MTH1 (4045/1078) NEN - Asociación de familias y amigos de pacientes enfermos de neuroblastoma (Nacional)