Ricardo Lucas Rodriguez

Profesor Ayudante Doctor
rlucas1@us.es
Área de conocimiento: Química Orgánica
Departamento: Química Orgánica y Farmaceútica
Grupo: CARBOHIDRATOS Y POLIMEROS (FQM-135)
Tipo Año Título Fuente
Artículo2022 Chemically tuning resveratrol for the effective killing of gram-positive pathogens. JOURNAL OF NATURAL PRODUCTS
Artículo2020 Altered paracellular permeability in intestinal cell monolayer challenged with lipopolysaccharide: Modulatory effects of pterostilbene metabolites FOOD AND CHEMICAL TOXICOLOGY
Revisión2020 In-depth study into polymeric materials in low-density gastroretentive formulations PHARMACEUTICS
Artículo2020 Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2019 Nanostructured Chitosan-based biomaterials for sustained and colon-specific resveratrol release INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2019 The Resveratrol Prodrug JC19 Delays Retinal Degeneration in rd10 Mice Advances in experimental medicine and biology
Ponencia2018 Bilingualism: the importance of speaking languages EDULEARN18 Proceedings
Artículo2018 Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies CHEMICAL SCIENCE
Artículo2018 Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design CELL
Ponencia2018 The mystery of labels: fake nutritional information? EDULEARN18 Proceedings
Artículo2018 Validation of Smart Nanoparticles as Controlled Drug Delivery Systems: Loading and pH-Dependent Release of Pilocarpine ACS OMEGA
Artículo2017 Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells JOURNAL OF FUNCTIONAL FOODS
Ponencia2017 Nutrition & labeling. A critical issue to be faced by future health graduates EDULEARN17 Proceedings
Artículo2017 pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems Journal of Drug Desing and Research
Artículo2017 Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates CHEMISTRY-A EUROPEAN JOURNAL
Ponencia2017 The epidemic of the twenty-first century: obesity. Keys to face it EDULEARN17 Proceedings
Artículo2017 Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells FOOD & FUNCTION
Nota2016 Back Cover: Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites (ChemBioChem 14/2016) CHEMBIOCHEM
Artículo2016 Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl-Resveratrol Prodrugs and Resveratrol Sulfate Metabolites CHEMBIOCHEM
Artículo2016 Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Artículo2016 Hydroxytyrosol and tyrosol sulfate metabolites protect against the oxidized cholesterol pro-oxidant effect in Caco-2 human enterocyte-like cells FOOD & FUNCTION
Ponencia2016 Sirt1 activators induced neuroprotection of photoreceptors in rd10 mice INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Capítulo2016 Synthesis of 1, 3, 4, 6-Tetra-O-Acetyl-2-Azido-2-Deoxy-α, β-d-Glucopyranose and 2-Azido-4, 6-OBenzylidene-2-Deoxy-α, β-d-Glucopyranose Carbohydrate Chemistry: Proven Synthetic Methods: Volume 1
Artículo2016 Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2015 Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: Relevance of their surface active properties and of the type of emulsifier FOOD CHEMISTRY
Artículo2015 Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo2014 Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate-DNA Stacking Interactions in Water JOURNAL OF ORGANIC CHEMISTRY
Artículo2013 Carbohydrate-DNA Interactions at G-Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5 '-End CHEMISTRY-A EUROPEAN JOURNAL
Artículo2013 Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Artículo2013 The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP) JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2012 Apolar carbohydrates as DNA capping agents CHEMICAL COMMUNICATIONS
Artículo2012 Effects of long-term consumption of low doses of resveratrol on diet-induced mild hypercholesterolemia in pigs: a transcriptomic approach to disease prevention JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2012 Resveratrol and Some Glucosyl, Glucosylacyl, and Glucuronide Derivatives Reduce Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria monocytogenes Scott A Adhesion to Colonic Epithelial Cell Lines JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2011 Highly Polar Carbohydrates Stack onto DNA Duplexes via CH/pi Interactions JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Artículo2011 Hydroxytyrosol glucuronides protect renal tubular epithelial cells against H2O2 induced oxidative damage CHEMICO-BIOLOGICAL INTERACTIONS
Artículo2011 Metabolites and tissue distribution of resveratrol in the pig MOLECULAR NUTRITION & FOOD RESEARCH
Artículo2011 Synthesis and characterization of phenolic antioxidants with surfactant properties: glucosyl- and glucuronosyl alkyl gallates TETRAHEDRON
Artículo2011 Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations MOLECULAR DIVERSITY
Artículo2010 Antioxidant Activity of Resveratrol in Several Fish Lipid Matrices: Effect of Acylation and Glucosylation JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2010 Preventive Oral Treatment with Resveratrol Pro-prodrugs Drastically Reduce Colon Inflammation in Rodents JOURNAL OF MEDICINAL CHEMISTRY
Artículo2010 Structure-Activity Relationship of Phenolic Antioxidants and Olive Components Olives and olive oil in health and disease prevention (Second Edition)
Artículo2010 Surface-Active Properties of Lipophilic Antioxidants Tyrosol and Hydroxytyrosol Fatty Acid Esters: A Potential Explanation for the Nonlinear Hypothesis of the Antioxidant Activity in Oil-in-Water Emulsions JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2010 Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose DNA Conjugates with Different Carbohydrate Presentation BIOCONJUGATE CHEMISTRY
Artículo2009 A concise synthesis of glucuronide metabolites of urolithin-B, resveratrol, and hydroxytyrosol CARBOHYDRATE RESEARCH
Artículo2009 Effect of Lipophilization of Hydroxytyrosol on Its Antioxidant Activity in Fish Oils and Fish Oil-in-Water Emulsions JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2008 Glycomimetic Inhibitors of Mycobacterial Glycosyltransferases: Targeting the TB Cell Wall CHEMBIOCHEM
Artículo2008 Mixture synthesis and "Charge tagging" based demixing: An efficient strategy for the preparation of heparan sulfate libraries JOURNAL OF COMBINATORIAL CHEMISTRY
Artículo2006 First synthesis of heparan sulfate tetrasaccha rides containing both N-acetylated and N-unsubstituted glucosamine - Search for putative 10E4 epitopes CHEMBIOCHEM
Artículo2004 Synthesis of glycosaminoglycan oligosaccharides - An unexpected inhibitory effect of a remote N-acetyl group upon trichloroacetimidate-mediated couplings EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2004 The activation of fibroblast growth factors (FGFs) by glycosaminoglycans: Influence of the sulfation pattern on the biological activity of FGF-1 CHEMBIOCHEM
Artículo2004 The heparin-Ca2+ interaction: the influence of the O-sulfation pattern on binding CARBOHYDRATE RESEARCH
Artículo2003 Synthesis and structural study of two new heparin-like hexasaccharides ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2002 The heparin-Ca2+ interaction: Structure of the Ca2+ binding site EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2022 31/05/2023 Investigador/a Development of nano and microstructured polymeric materials with gastroretentive action for oral drug administration (US-1380587) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
01/09/2021 31/08/2024 Investigador/a Preparación sostenible de hidrogeles superporosos con biodegradabilidad mejorada mediante la formación de redes interpenetradas (PID2020-115916GB-I00) Ministerio de Ciencia e Innovación (Nacional)

Patentes

Nº Solicitud Fecha Solicitud Fecha Concesión Nombre
P201130985 14/06/2011 08/11/2013 Derivados de galatos de alquilo como antioxidantes y surfactantes
E01947467 05/07/2001 09/08/2006 Nuevos disacáridos con acción antiartrosica