María Dolores Herrera González

Catedrática de Universidad
mdherrera@us.es
Área de conocimiento: Farmacología
Departamento: Farmacología
Grupo: FARMACOLOGÍA CARDIOVASCULAR (CTS-178)
Prog. doctorado: Programa de Doctorado en Farmacia (RD. 99/2011)
Tipo Año Título Fuente
Artículo2021 Days needed for the disappearance of a cough due to the use of an angiotensin-converting enzyme inhibitor and identification of predisposing factors associated with its appearance in a clinical cohort of hypertensive patients JOURNAL OF CLINICAL PHARMACOLOGY
Letter2021 Response to letter to the editor from Dr. Cimolai JOURNAL OF CLINICAL PHARMACOLOGY
Artículo2020 Pomace Olive Oil Concentrated in Triterpenic Acids Restores Vascular Function, Glucose Tolerance and Obesity Progression in Mice NUTRIENTS
Artículo2017 Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production FOOD & FUNCTION
Revisión2017 Contribution of ferulic acid, gamma-oryzanol and tocotrienols to the cardiometabolic protective effects of rice bran JOURNAL OF FUNCTIONAL FOODS
Artículo2017 Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2017 Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE-/- mice EUROPEAN JOURNAL OF NUTRITION
Capítulo2017 Obtention and nutraceutical characterization of an enzymatic extract derived from rice bran Nutraceuticals: Prospects, Sources and Role in Health and Disease
Ponencia2017 Pomace olive oil enriched in oleanolic acid restores vascular dysfunction and metabolic parameters in mice fed a high fat diet BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2017 Rice bran enzymatic extract reduces atherosclerotic plaque development and steatosis in high-fat fed ApoE-/- mice NUTRITION
Artículo2016 Atherosclerosis-related inflammation and oxidative stress are improved by rice bran enzymatic extract JOURNAL OF FUNCTIONAL FOODS
Artículo2016 Diet supplementation with rice bran enzymatic extract restores endothelial impairment and wall remodelling of ApoE(-/-) mice microvessels ATHEROSCLEROSIS
Artículo2016 Rice bran prevents high-fat diet-induced inflammation and macrophage content in adipose tissue EUROPEAN JOURNAL OF NUTRITION
Artículo2015 Non-clinical reports Pharmaceuticals Policy and Law
Artículo2015 Phenolic content of extra virgin olive oil is essential to restore endothelial dysfunction but not to prevent vascular inflammation in atherosclerotic lesions of Apo E deficient mice JOURNAL OF FUNCTIONAL FOODS
Ponencia2015 Rice bran enzymatic extract diet supplementation reduces oxidative stress and inflammation associated to atherosclerosis disease in apoe(-/-) mice BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2015 Rice bran enzymatic extract prevents atherosclerotic plaque development through its hipolipidemic and antiinflamatory effects ATHEROSCLEROSIS
Ponencia2015 Rice bran enzymatic extract prevents endothelial dysfunction and restores structural, mechanical and myogenic alterations of resistance arteries in apoe(-/-) mice BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2015 Specific requirements regarding module 4 Pharmaceuticals Policy and Law
Artículo2015 Structural, mechanical and myogenic properties of small mesenteric arteries from ApoE KO mice: Characterization and effects of virgin olive oil diets ATHEROSCLEROSIS
Artículo2014 Influence of pharmaceutical care on the delayed emesis associated with chemotherapy INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
Artículo2014 Microvascular disorders in obese Zucker rats are restored by a rice bran diet NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
Ponencia2014 Oleaster, a new virgin olive oil protects against atherosclerotic process in apoe ko mice by reducing inflammatory mediators and superoxide production ATHEROSCLEROSIS
Ponencia2014 Opto-mechanical microbridles for the determination of structural and functional properties of small resistance arteries Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Ponencia2014 Rice bran enzymatic extract reduces atherosclerotic lesions in apo e (-/-) mice BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2014 Rice bran enzymatic extract reduces oxidative stress and restores mesenteric endothelium dependant dilatation in apo e (-/-) mice ATHEROSCLEROSIS
Artículo2014 Rice bran enzymatic extract-supplemented diets modulate adipose tissue inflammation markers in Zucker rats NUTRITION
Ponencia2014 Virgin olive oil restores structural, myogenic and functional alterations of small mesenteric arteries from apoe ko mice ATHEROSCLEROSIS
Ponencia2013 A rice bran supplemented-diet restored the edhf-contribution to the vascular function of resistance arteries from obese zucker rats BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2013 Antioxidant protection of grape pomace enzymatic extract and its major polyphenols upon nadph oxidase activation and superoxide dismutase inhibition BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2013 Oleaster (r) improves endothelial dysfunction associated to atherosclerosis by reducing inflammatory mediators and superoxide anion production BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2013 Protección antioxidante de un extracto enzimático de orujo de la uva y sus polifenoles mayoritarios sobre la activación de NADPH oxidasa y la inhibición de superóxido dismutasa Actualidad en Farmacología y Terapéutica
Artículo2013 Rice bran enzymatic extract restores endothelial function and vascular contractility in obese rats, by reducing vascular inflammation and oxidative stress JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Artículo2013 Water-soluble rice bran enzymatic extract attenuates dyslipidemia, hypertension and insulin resistance in obese Zucker rats EUROPEAN JOURNAL OF NUTRITION
Artículo2012 Cell-based microfluidic device for screening anti-proliferative activity of drugs in vascular smooth muscle cells BIOMEDICAL MICRODEVICES
Artículo2012 Comparative study on the vasorelaxant effects of three alkaloids-rich extracts from seeds of Peganum harmala L Journal of Natural Remedies
Artículo2012 Endothelium-dependent vasodilator and antioxidant properties of a novel enzymatic extract of grape pomace from wine industrial waste FOOD CHEMISTRY
Artículo2012 Propionyl-L-carnitine Corrects Metabolic and Cardiovascular Alterations in Diet-Induced Obese Mice and Improves Liver Respiratory Chain Activity PLOS ONE
Revisión2011 Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders VASCULAR HEALTH AND RISK MANAGEMENT
Póster2011 Endothelium-dependent vasodilating and antioxidant properties of a novel enzymatic extract of grape pomace from wine industrial wast BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2011 Gamma-oryzanol decreases nitric oxide and tnf-a production by stimulated murine macrophages BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Ponencia2011 Mechanisms implicated in the effects of propionyl-l-carnitine on the obesity-related insulin resistance state BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Revisión2011 Pharmacological effects and clinical applications of propionyl-L-carnitine NUTRITION REVIEWS
Ponencia2011 Treatment with a novel rice bran enzymatic extract improves cardiometabolic risk factors in obese zucker rats BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
Artículo2010 Chronic Treatment With the Cannabinoid 1 Antagonist Rimonabant Altered Vasoactive Cyclo-oxygenase-Derived Products on Arteries From Obese Zucker Rats JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Revisión2010 Endothelial dysfunction and aging: An update AGEING RESEARCH REVIEWS
Ponencia2010 Propionyl-1-carnitine prevent metabolic and cardiovascular alterations in a model of diet-induced obesity FUNDAMENTAL & CLINICAL PHARMACOLOGY
Ponencia2010 Vasorelaxant effect induced by a grape pomace extract obtained by a novel enzymatic process HYPERTENSION
Artículo2009 Effects of Chronic Treatment With the CB1 Antagonist, Rimonabant on the Blood Pressure, and Vascular Reactivity of Obese Zucker Rats OBESITY
Artículo2009 Effects of pomace olive oil-enriched diets on endothelial function of small mesenteric arteries from spontaneously hypertensive rats BRITISH JOURNAL OF NUTRITION
Revisión2009 Mechanism involved in aged-related endothelial dysfuntion MEDICINA CLINICA
Artículo2009 Oral supplementation of propionyl-L-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats BRITISH JOURNAL OF NUTRITION
Artículo2008 Effects of HMG-CoA reductase inhibition by simvastatin on vascular dysfunction induced by lipopolysaccharide in rats PHARMACOLOGY
Ponencia2008 Effects of long-term propionyl-l-carnitine treatment on metabolic syndrome developed by obese zucker rats METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Capítulo2008 El aprendizaje tutelado como método de enseñanza en Farmacología y Farmacoterapia Experiencia de innovación universitaria: curso 2005/2006
Artículo2008 Oleanolic acid induces prostacyclin release in human vascular smooth muscle cells through a cyclooxygenase-2-dependent mechanism JOURNAL OF NUTRITION
Artículo2008 Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide BRITISH JOURNAL OF PHARMACOLOGY
Ponencia2008 Rimonabant modifies participation of no and cox products on vascular function of obese zucker rats METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
Artículo2007 Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR JOURNAL OF VASCULAR RESEARCH
Artículo2007 L-carnitine and its propionate: Improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms FREE RADICAL RESEARCH
Artículo2007 Pomace olive oil improves endothelial function in spontaneously hypertensive rats by increasing endothelial nitric oxide synthase expression AMERICAN JOURNAL OF HYPERTENSION
Artículo2006 Functional Properties of Pentacyclic Triterpenes Contained in "Orujo" Olive Oil CURRENT NUTRITION & FOOD SCIENCE
Ponencia2006 Oleanolic acid potenciates the up-regulation of cyclooxygenase-2 (Cox-2) induced by HDL in human vascular smooth muscle cells EUROPEAN HEART JOURNAL
Artículo2006 Triterpenic compounds from "orujo" olive oil elicit vasorelaxation in aorta from spontaneously hypertensive rats JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo2006 Vasorelaxant effects of harmine and harmaline extracted from Peganum harmala L. seed's in isolated rat aorta PHARMACOLOGICAL RESEARCH
Artículo2005 Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L Journal of Natural Remedies
Artículo2005 L-carnitine and propionyl-L-camitine improve endothelial dysfunction in spontaneously hypertensive rats: Different participation of NO and COX-products LIFE SCIENCES
Ponencia2005 Oleanolic acid, a component in residues of olive oil, dilates isolated arteries by release of endothelium-derived relaxing factors ATHEROSCLEROSIS SUPPLEMENTS
Ponencia2005 Oleanolic acid, a component in residues of olive oil, dilates isolated arteries by release of endothelium-derived relaxing factors HYPERTENSION
Ponencia2005 Oleanolic acid, a component of olive oil residues, causes calcium-independent release of endothelium-derived nitric oxide HYPERTENSION
Artículo2005 Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin PHARMACOLOGY
Artículo2004 Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats BRITISH JOURNAL OF NUTRITION
Ponencia2004 Beneficial vascular effects of oleanolic acid and erythrodiol ATHEROSCLEROSIS SUPPLEMENTS
Ponencia2004 Pleiotropic effects of sinivastin on endothelial dysfunction from aged rats: Role of NO and cyclo-oxygenase products ATHEROSCLEROSIS SUPPLEMENTS
Artículo2004 Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in 'orujo' olive oil, on rat aorta BRITISH JOURNAL OF NUTRITION
Ponencia2004 Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin FUNDAMENTAL & CLINICAL PHARMACOLOGY
Ponencia2004 The vascular activity of oleanolic and maslinic acid, orujo olive oil triterpenoids, in isolated aorta FUNDAMENTAL & CLINICAL PHARMACOLOGY
Artículo2003 Effects of simastatin on endothelial function after chronic inhibition of nitric oxide synthase by L-NAME JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Artículo2003 Hypolipidemic and hypocholesterolemic effect of argan oil (Argania spinosa L.) in Meriones shawi rats JOURNAL OF ETHNOPHARMACOLOGY
Artículo2002 Endothelium-dependent vasorelaxation induced by L-carnitine in isolated aorta from normotensive and hypertensive rats JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo2002 Relaxant activity of methanolic extract from seeds of Peganum harmala on isolated rat aorta THERAPIE
Artículo2002 Simvastatin improves endothelial function in spontaneously hypertensive rats through a superoxide dismutase mediated antioxidant effect JOURNAL OF HYPERTENSION
Artículo2001 A pharmacological study of Cecropia obtusifolia Bertol aqueous extract JOURNAL OF ETHNOPHARMACOLOGY
Artículo2001 Action of tacrine on muscarinic receptors in rat intestinal smooth muscle Journal of autonomic pharmacology
Artículo2001 Effect of simvastatin on vascular smooth muscle responsiveness: involvement of Ca2+ homeostasis EUROPEAN JOURNAL OF PHARMACOLOGY
Artículo2001 Effects of dietary oleic-rich oils (virgin olive and high-oleic-acid sunflower) on vascular reactivity in Wistar-Kyoto and spontaneously hypertensive rats BRITISH JOURNAL OF NUTRITION
Artículo2000 Characterization of endothelial factors involved in the vasodilatory effect of simvastatin in aorta and small mesenteric artery of the rat BRITISH JOURNAL OF PHARMACOLOGY
Artículo2000 Endothelium modulates contractile response to simvastatin in rat aorta ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo1999 Effects of chronic treatment with simvastatin on endothelial dysfunction in spontaneously hypertensive rats JOURNAL OF HYPERTENSION
Artículo1999 Interés terapéutico de las estatinas en el tratamiento de la aterosclerosis ARS PHARMACEUTICA
Artículo1998 Cardiovascular effects of lovastatin in normotensive and spontaneously hypertensive rats GENERAL PHARMACOLOGY
Artículo1998 In vitro scavenger and antioxidant properties of hesperidin and neohesperidin dihydrochalcone PHYTOMEDICINE
Artículo1997 Spasmolytic effects of tetrazepam on rat duodenum and guinea-pig ileum PHARMACOLOGICAL RESEARCH
Artículo1997 Uterine relaxant effect of zolpidem: A comparison with other smooth muscle relaxants ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Artículo1997 Vasodilating effects of tetrazepam in isolated vascular smooth muscles: Comparison with cromakalim and diltiazem PHARMACOLOGICAL RESEARCH
Artículo1996 Effect of hesperidin and neohesperidin dihydrochalcone on central nervous system FITOTERAPIA
Artículo1996 Effects of flavonoids on rat aortic smooth muscle contractility: Structure-activity relationships GENERAL PHARMACOLOGY
Artículo1996 Effects of tetrazepam on vascular smooth muscle of rat and rabbit aortae Pharmaceutical Sciences
Artículo1996 Eficacia, seguridad y tolerabilidad del policosanol en pacientes con hipercolesterolemia tipo II: Estudio abierto Prensa Medica Argentina
Artículo1996 Hesperidin and neohesperidin dihydrochalcone on different experimental models of induced gastric ulcer PHYTOTHERAPY RESEARCH
Artículo1996 Pharmacological actions of naringin on alpha, beta-adrenoceptors and uptake of noradrenaline in rat isolated vas deferens PHYTOTHERAPY RESEARCH
Artículo1996 Relaxant effect of tetrazepam on rat uterine smooth muscle: Role of calcium movement JOURNAL OF PHARMACY AND PHARMACOLOGY
Artículo1996 Smooth muscle relaxant effects of tetrazepam on isolated guinea-pig and rat trachealis Journal of autonomic pharmacology
Letter1995 Effects of ixanthus-viscosus extracts on the central-nervous-system PLANTA MEDICA
Nota1995 Spasmolytic action of the essential oil of achillea ageratum l in rats PHYTOTHERAPY RESEARCH
Artículo1993 Effect of naringin and naringenin on contractions induced by noradrenaline in rat vas-deferens .1. evidence for postsynaptic alpha-2-adrenergic receptor GENERAL PHARMACOLOGY
Artículo1992 Effects of genistein, an isoflavone isolated from genista-tridentata, on isolated guinea-pig ileum and guinea-pig ileal myenteric plexus PLANTA MEDICA
Artículo1991 The spasmolytic activity of Genista tridentata L. Plantes Medicinales et Phytotherapie
Artículo1990 Contribution to the pharmacodynamic study of Pycnocomon rutifolium (Vahl.) Hoffmanns and Link. Antiinflammatory activity and antibacterial activity Annales Pharmaceutiques Françaises
Artículo1990 The polyphenolic constituents of Genista tridentata L. Plantes Medicinales et Phytotherapie
Artículo1989 Contribution to the pharmacodynamic study of Pycnocomon rutifolium (Vahl). Hoffmanns. and Link. Analgesic activity and antipyretic activity Annales Pharmaceutiques Françaises

Tesis dirigidas/tutorizadas:12
Fecha lectura Título Rol
29/06/2021 EFECTOS SECUNDARIOS MAS FRECUENTES DE LOS IECA EN UNA CONSULTA HOSPITALARIA DE HIPERTENSIÓN ARTERIAL: TIEMPO DE DESAPARICIÓN DE LA TOS POR IECA TRAS INTERRUMPIR EL TRATAMIENTO Director/a, Tutor/a
29/09/2017 EFECTOS DE OLEASTER®, UN ACEITE DE OLIVA VIRGEN EXTRA RICO EN POLIFENOLES, SOBRE LA FUNCIÓN VASCULAR EN UN MODELO ANIMAL DE ATEROSCLEROSIS Director/a
01/02/2017 EVALUACIÓN DEL EFECTO PROTECTOR DE UN EXTRACTO ENZIMÁTICO DE SALVADO DE ARROZ FRENTE AL ESTADO INFLAMATORIO PRESENTE EN EL PROCESO ATEROSCLERÓTICO Director/a
28/11/2014 CARACTERIZACIÓN DE LAS PROPIEDADES FUNCIONALES A NIVEL CARDIOVASCULAR Y DEL SINDROME METABÓLICO DE UN EXTRACTO ENZIMÁTICO DE SALVADO DE ARROZ Director/a
08/11/2011 EFECTOS METABÓLICOS Y CARDIOVASCULARES DE PROPIONIL-L-CARNITINA SOBRE DISTINTOS MODELOS DE OBESIDAD Director/a
24/10/2006 EFECTOS DEL ACEITE DE ORUJO Y DEL ÁCIDO OLEANÓLICO SOBRE EL ENDOTELIO Y LA FUNCIÓN VASCULAR Director/a
12/12/2003 EFECTOS SOBRE LA FUNCIÓN VASCULAR DE L-CARNITINA Y SU DERIVADO ACILADO PROPIONIL-L.CARNITINA Director/a
06/05/2003 EFECTO DE TACRINA SOBRE MUSCULATURA LISA VASCULAR Y NO VASCULAR AISLADA DE RATA Director/a
29/06/1999 EFECTO DE SIMVASTATINA SOBRE LA FUNCION VASCULAR: IMPORTANCIA DEL ENDOTELIO Director/a
1999 Actividad farmacológica de Cecropia obtusifolia. Bertol Director/a
1996 Eficacia de hesperidina y neohesperidina en la úlcera gástrica experimental y mecanismos relacionados con su actividad Director/a
1996 Estudio comparativo de tetrazepam y diltiazem en musculatura lisa traqueal Director/a

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
21/06/2010 31/12/2013 Responsable Investigación y desarrollo de nuevas posibilidades de aplicaciones terapéuticas en el aceite de oliva (IPT-060000-2010-28) Ministerio de Ciencia e Innovación (Nacional)
01/10/2006 30/09/2009 Investigador/a Contaminación de pescados de consumo público con microcistinas: métodos in vivo in vitro de evaluación de toxicidad y prevención de riesgos tóxicos derivados (AGL2006-06523) Ministerio de Educación y Ciencia (Nacional)
01/03/2010 29/02/2012 Responsable Obtención y escalado a planta piloto de extractos enzimáticos procedentes de co-productos agroindustriales: caracterización de las propiedades funcionales a nivel cardiovascular y síndrome metabólico (TRA2009_0263_02) Ministerio de Ciencia e Innovación (Nacional)
01/03/2010 29/02/2012 Responsable Obtención y escalado a planta piloto de extractos enzimáticos procedntes de co-productos agroindustriales.: caracterización de las propiedades funcionales a nivel cardiovascular y síndrome metabólico (TRA2009_0263_01) Ministerio de Ciencia e Innovación (Nacional)
01/01/2010 31/12/2012 Responsable Caracterización de las propiedades funcionales a nivel cardiovascular y del síndrome metabólico de un extracto enzimático del salvado de arroz (AGL2009-11559) Ministerio de Ciencia e Innovación (Nacional)
01/02/2020 31/01/2022 Responsable Nanotransportadores Activos de Cannabinoides para el Tratamiento de la Aterosclerosis (US-1263053) Junta de Andalucía (Consejería de Economía y Conocimiento) (Autonómico)

Ayudas

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
16/06/2011 17/06/2011 Responsable 3ª Reunión de Jóvenes Farmacólogos de Andalucía (PP2011-01-033) Universidad de Sevilla (Local)