Inmaculada Fernández Fernández

Catedrática de Universidad
inmaff@us.es
Área de conocimiento: Química Orgánica
Departamento: Química Orgánica y Farmaceútica
Grupo: ESTEREOQUIMICA Y SINTESIS ASIMETRICA (FQM-102)
Prog. doctorado: Programa de Doctorado en Farmacia (RD. 99/2011)
Tipo Año Título Fuente
Artículo2022 Benzothiazole derivatives endowed with antiproliferative activity in paraganglioma and pancreatic cancer cells: structure–activity relationship studies and target prediction analysis PHARMACEUTICALS
Artículo2022 Biologically Relevant Micellar Nanocarrier Systems for Drug Encapsulation and Functionalization of Metallic Nanoparticles. NANOMATERIALS
Artículo2022 Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiforme EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2022 Immunomodulatory effects of (R)-sulforaphane on LPS-activated murine immune cells: molecular signaling pathways and epigenetic changes in histone markers PHARMACEUTICALS
Artículo2021 Carbohydrate-based NK1R antagonists with broad-spectrum anticancer activity. JOURNAL OF MEDICINAL CHEMISTRY
Corrección2021 Erratum: Clickable iron oxide NPs based on catechol derived ligands: Synthesis and characterization (Soft Matter (2020) 16 (3257–3266) DOI: 10.1039/C9SM02512J) SOFT MATTER
Revisión2020 2-substituted benzothiazoles as antiproliferative agents: novel insights on structure-activity relationships EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo2020 Clickable iron oxide NPs based on catechol derived ligands: Synthesis and characterization SOFT MATTER
Artículo2019 N -Isopropylsulfinylimines vs. N-tert -butylsulfinylimines in the stereoselective synthesis of sterically hindered amines: An improved synthesis of enantiopure (R)- And (S)-rimantadine and the trifluoromethylated analogues ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2019 Steric Tuning of Sulfinamide/Sulfoxides as Chiral Ligands with C1, Pseudo- meso, and Pseudo- C2 Symmetries: Application in Rhodium(I)-Mediated Arylation ORGANIC LETTERS
Artículo2019 Synthesis and Characterization of New Biocompatible Amino Amphiphilic Compounds Derived from Oleic Acid as Nanovectors for Drug Delivery Proceedings (MDPI)
Artículo2018 An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols ADVANCED SYNTHESIS & CATALYSIS
Ponencia2018 Density functional theory insights into rhodium-catalyzed addition of arylboronic acids to ketones ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
Artículo2018 NMR study on the stabilization and chiral discrimination of sulforaphane enantiomers and analogues by cyclodextrins CARBOHYDRATE POLYMERS
Artículo2017 Biologically Active Isothiocyanates: Protecting Plants and Healing Humans STUDIES IN NATURAL PRODUCTS CHEMISTRY, VOL 53
Artículo2017 Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Ponencia2017 Diseño racional de nuevos antagonistas de los receptores NK-1 asistido por ordenador: síntesis y evaluación biológica Libro de actas del Congreso CUICIID 2017
Ponencia2017 Diseño racional de nuevos antagonistas de los receptores NK-1 asistido por ordenador: síntesis y evaluación biológica Libro de actas del Congreso CUICIID 2017
Ponencia2017 First principles study of sulfinamido-olefin ligands in the rhodium-catalyzed addition of arylboronic acids to ketones ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
Artículo2017 Pyrene-tagged carbohydrate-based mixed P/S ligand: spacer effect on the Rh(I)-catalyzed hydrogenation of methyl alpha-acetamidocinnamate ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2016 Pseudo enantiomeric mixed S/P ligands derived from carbohydrates for the 1,4-addition of phenyl boronic acid to cyclohexenone RSC ADVANCES
Artículo2016 Stereoselective Synthesis of P-Stereogenic N-Phosphinyl Compounds EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2016 Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines ORGANIC LETTERS
Artículo2016 Tuning of glyconanomaterial shape and size for selective bacterial cell agglutination JOURNAL OF MATERIALS CHEMISTRY B
Resumen congreso2015 Síntesis estereoselectiva de una nueva familia de beta-aminoésteres de interés farmacológico como inhibidores potenciales de la agregación plaquetaria. Biosaia
Artículo2015 Studies on the diastereoselective oxidation of 1-thio-beta-D-glucopyranosides: synthesis of the usually less favoured R-S sulfoxide as a single diastereoisomer ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2015 Synthesis of 1D-glyconanomaterials by a hybrid noncovalent-covalent functionalization of single wall carbon nanotubes: a study of their selective interactions with lectins and with live cells NANOSCALE
Artículo2014 "Sulfolefin": a mixed sulfinamido-olefin ligand in enantioselective rhodium-catalyzed addition of arylboronic acids to trifluoromethyl ketones ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2014 DMAP-Catalysed Sulfinylation of Diacetone-D-Glucose: Improved Method for the Synthesis of Enantiopure tert-Butyl Sulfoxides and tert-Butanesulfinamide EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2014 Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Capítulo2013 Aldol-Type Reactions Carbohydrates - Tools for Stereoselective Synthesis
Artículo2013 Asymmetric Rhodium-Catalyzed 1,4- and 1,2-Additions of Arylboronic Acids to Activated Ketones in Water at Room Temperature Using a Mixed Sulfur-Olefin Ligand. ADVANCED SYNTHESIS & CATALYSIS
Capítulo2013 Cyclopropanation Carbohydrates - Tools for Stereoselective Synthesis
Artículo2013 Evaluation of trace element contamination changes in soils using a new normalization factor Application to the Guadiamar soils (SW Spain) affected by a mine spill in 1998 JOURNAL OF GEOCHEMICAL EXPLORATION
Artículo2013 Flexible C-2-Symmetric Bis-Sulfoxides as Ligands in Enantioselective 1,4-Addition of Boronic Acids to Electron-Deficient Alkenes JOURNAL OF ORGANIC CHEMISTRY
Artículo2013 Glyconanosomes: Disk-Shaped Nanomaterials for the Water Solubilization and Delivery of Hydrophobic Molecules ACS NANO
Artículo2013 Proline-coated gold nanoparticles as a highly efficient nanocatalyst for the enantioselective direct aldol reaction in water RSC ADVANCES
Capítulo2013 Reaction of Enolates Carbohydrates - Tools for Stereoselective Synthesis
Artículo2013 Supramolecular Diversity through Click Chemistry: Switching from Nanomicelles to 1D-Nanotubes and Tridimensional Hydrogels CHEMISTRY OF MATERIALS
Artículo2013 Synthesis and non-covalent functionalization of carbon nanotubes rings: new nanomaterials with lectin affinity NANOTECHNOLOGY
Artículo2012 'ClickCarlb': modular sugar based ligands via click chemistry TETRAHEDRON LETTERS
Artículo2012 "Sulfolefin": Highly modular mixed S/Olefin ligands for enantioselective Rh-catalyzed 1,4-addition ORGANIC & BIOMOLECULAR CHEMISTRY
Ponencia2012 Molecular imaging of experimental thyroid proliferative disorders FEBS JOURNAL
Artículo2012 P/S ligands derived from carbohydrates in Rh-catalyzed hydrosilylation of ketones ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2011 Copper-Catalyzed Azide-Alkyne Cycloaddition in the Synthesis of Polydiacetylene: "Click Glycoliposome" as Biosensors for the Specific Detection of Lectins CHEMISTRY-A EUROPEAN JOURNAL
Artículo2010 Chiral sulfur derivatives in the allylation of acyl hydrazones: C-2-symmetric bis-sulfinamides as enhanced chiral organic promoters ORGANIC & BIOMOLECULAR CHEMISTRY
Artículo2010 Enantiodivergent Approach to Trifluoromethylated Amines: A Concise Route to Both Enantiomeric Analogues of Calcimimetic NPS R-568 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2010 Improved Non-Covalent Biofunctionalization of Multi-Walled Carbon Nanotubes Using Carbohydrate Amphiphiles with a Butterfly-Like Polyaromatic Tail Nano Research
Artículo2009 A phase II randomized trial of gemcitabine-docetaxel versus gemcitabine-cisplatin in patients with advanced non-small cell lung carcinoma CANCER CHEMOTHERAPY AND PHARMACOLOGY
Capítulo2009 Asymmetric Catalysis Using Sulfoxides as Ligands Organosulfur Chemistry in Asymmetric Synthesis
Artículo2009 Axial Chirality Control During Suzuki-Miyaura Cross-Coupling Reactions: The tert-Butylsulfinyl Group as an Efficient Chiral Auxiliary ORGANIC LETTERS
Artículo2009 Enantiopure Sulforaphane Analogues with Various Substituents at the Sulfinyl Sulfur: Asymmetric Synthesis and Biological Activities JOURNAL OF ORGANIC CHEMISTRY
Artículo2009 Non-covalent functionalization of carbon nanotubes with glycolipids: glyconanomaterials with specific lectin-affinity SOFT MATTER
Ponencia2009 Sulforaphane and analogues as potent chemopreventive agents DRUGS OF THE FUTURE
Artículo2009 Tailoring carbon nanotube surfaces with glyconanorings: New bionanomaterials with specific lectin affinity CHEMICAL COMMUNICATIONS
Artículo2008 Asymmetric enamide hydrogenation using phosphinite thioglycosides: Synthesis of D- and L-aminoesters using D-sugars as catalyst precursors ORGANIC LETTERS
Artículo2008 N-isopropylsulfinylimines as useful intermediates in the synthesis of chiral amines: Expeditive asymmetric synthesis of the calcimimetic (+)-NPS R-568 JOURNAL OF ORGANIC CHEMISTRY
Artículo2008 New phosphinite thioglycosides for asymmetric hydrogenation SYNFACTS Highlights in Current Synthetic Organic Chemistry
Artículo2008 New sulfur-phosphine ligands derived from sugars: synthesis and application in palladium-catalyzed allylic alkylation and in rhodium asymmetric hydrogenation ARKIVOC
Artículo2007 C-2-Symmetric bissulfoxides as organocatalysts in the allylation of benzoyl hydrazones: Spacer and concentration effects ORGANIC LETTERS
Artículo2007 Enantioselective organocatalytic oxidation of functionalized sterically hindered disulfides ORGANIC LETTERS
Artículo2007 How does the achiral base decide the stereochemical outcome in the dynamic kinetic resolution of sulfinyl chlorides? A computational study ADVANCED SYNTHESIS & CATALYSIS
Artículo2006 Mechanism of the base-assisted displacement of chloride by alcohol in sulfinyl derivatives JOURNAL OF ORGANIC CHEMISTRY
Artículo2006 Mixed S/N and S/P/N ligands from carbohydrates: Synthesis and application in palladium-catalyzed allylic alkylation INORGANICA CHIMICA ACTA
Artículo2006 Sulfur-sulfur-based ligands derived from D-sugars: Synthesis of Pd-II complexes, application in palladium-catalyzed allylic alkylation for the synthesis of both members of enantiomer pairs, and structural studies EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Artículo2005 C-2-symmetric bis-sulfoxides: Synthesis of both enantiomers and utilization in organometallic chemistry and in asymmetric catalysis Phosphorus, Sulfur and Silicon and Related Elements
Artículo2005 C-2-symmetric bis-thioglycosides as useful ligands in palladium-catalyzed asymmetric allylic alkylation: Synthesis of both enantiomers using natural sugars as ligand precursors Phosphorus, Sulfur and Silicon and Related Elements
Artículo2005 Mixed S/P ligands from carbohydrates: Synthesis and utilization in asymmetric catalysis Phosphorus, Sulfur and Silicon and Related Elements
Artículo2005 Phosphinite thioglycosides derived from natural D-sugars as useful P/S ligands for the synthesis of both enantiomers in palladium-catalyzed asymmetric substitution SYNLETT
Artículo2005 The isopropyl- and tert-butylsulfinyl groups in asymmetric synthesis: A comparative study Phosphorus, Sulfur and Silicon and Related Elements
Artículo2005 The isopropylsulfinyl group: A useful chiral controller for the asymmetric aziridination of sulfinylimines and the organocatalytic allylation of hydrazones ORGANIC LETTERS
Artículo2004 Highly diastereoselective formation of C-2-symmetric bis-thioglycoside Pd(II) complexes: the role of the exo anomeric effect CHEMICAL COMMUNICATIONS
Artículo2004 Stereoselective addition of alpha-sulfinyl carbanions to N-p-tolylsulfinylketimines: Synthesis of optically pure 1,2,2 '-trialkyl-2-aminoethanols JOURNAL OF ORGANIC CHEMISTRY
Artículo2003 C-2-symmetric bis-thioglycosides as new ligands for palladium-catalyzed allylic substitutions TETRAHEDRON LETTERS
Artículo2003 Highly diastereoselective oxidation of 2-amino-2-deoxy-1-thio-beta-D-glucopyranosides: Synthesis of imino sulfinylglycosides JOURNAL OF ORGANIC CHEMISTRY
Revisión2003 Recent developments in the synthesis and utilization of chiral sulfoxides CHEMICAL REVIEWS
Revisión2002 Dynamic kinetic transformation of sulfinyl chlorides: Synthesis of enantiomerically pure C-2-symmetric bis-sulfoxides JOURNAL OF ORGANIC CHEMISTRY
Artículo2001 Monodentate phosphites with carbohydrate substituents and their application in rhodinm catalysed asymmetric hydrosilylation reactions TETRAHEDRON-ASYMMETRY
Artículo2000 Additions of enantiopure α-sulfinyl carbanions to (S)-N-sulfinimines: Asymmetric synthesis of β-amino sulfoxides and β-amino alcohols JOURNAL OF ORGANIC CHEMISTRY
Artículo2000 C-2-symmetric bis-sulfoxide: Highly diastereoselective 1,4-addition to stabilised Michael acceptors TETRAHEDRON
Artículo2000 Dynamic kinetic resolution of bis-sulfinyl chlorides: A general enantiodivergent synthesis of C-2-symmetric bis-sulfinate esters and bis-sulfoxides JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Artículo1999 A generalization of the base effect on the diastereoselective synthesis of sulfinic and phosphinic esters TETRAHEDRON LETTERS
Artículo1998 Enantiomerically pure α-alkylidene β-amino esters from asymmetric addition of metal dienolates to N-sulfinylimines JOURNAL OF ORGANIC CHEMISTRY
Artículo1998 Highly stereoselective hydrocyanation of optically pure alpha-sulfinylaldehydes TETRAHEDRON-ASYMMETRY
Artículo1998 Synthesis of enantiomerically pure (R)- and (S)-2-ethoxycarbonylmethyl- 2-hydroxy-cyclohexanones TETRAHEDRON-ASYMMETRY
Artículo1997 Arousal psicofisiológico y autoinformado: diferencias entre sujetos con patrón de conducta Tipo A y Tipo B REVISTA DE PSICOLOGIA SOCIAL
Artículo1997 General method for asymmetric synthesis of alpha-methylsulfinyl ketones: Application to the synthesis of optically pure oxisuran and bioisosteres JOURNAL OF ORGANIC CHEMISTRY
Artículo1996 Asymmetric aziridination by reaction of chiral N-sulfinylimines with sulfur ylides: Stereoselectivity improvement by use of tert-butylsulfinyl group as chiral auxiliary TETRAHEDRON-ASYMMETRY
Artículo1996 Unprecedented base effect on the synthesis of chiral phosphinate esters: A new route to P-chiral phosphine oxides of high enantiomeric purity TETRAHEDRON-ASYMMETRY
Letter1995 Michael additions of alpha-sulfinyl and alpha-sulfonyl carbanions - The unprecedented reaction of beta-keto sulfoxides and beta-keto sulfones with highly stabilized michael acceptors JOURNAL OF ORGANIC CHEMISTRY
Artículo1995 On the reaction of chiral sulfinimines with sulfur ylides: a novel route to the asymmetric aziridination TETRAHEDRON LETTERS
Artículo1994 Asymmetric-synthesis of optically pure tert-butyl sulfoxides using the dag-methodology TETRAHEDRON LETTERS
Artículo1993 Asymmetric-synthesis of alkyl and aryl sulfinates of dag - an improved and general-route to both enantiomerically pure sulfoxides PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Artículo1993 Asymmetric-synthesis of biologically-active compounds bearing a chiral sulfinyl group PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Artículo1993 C2-symmetrical bis-sulfoxides as chiral ligands in metal-catalyzed asymmetric diels-alder reactions TETRAHEDRON LETTERS
Artículo1992 Asymmetric Synthesis of Alkane- and Arenesulfinates of Diacetone-d-glucose (DAG): An Improved and General Route to Both Enantiomerically Pure Sulfoxides JOURNAL OF ORGANIC CHEMISTRY
Artículo1992 Asymmetric-synthesis of beta-amino-gamma-hydroxysulfoxides TETRAHEDRON LETTERS
Artículo1991 An efficient synthesis of both enantiomers of chiral non racemic methylsulfoxides from DAG TETRAHEDRON LETTERS
Artículo1991 Asymmetric-synthesis of the C-3/C-9 fragment of (-)-aspicilin TETRAHEDRON LETTERS
Artículo1991 Asymmetric-synthesis of the macrolide (-)-aspicilin TETRAHEDRON-ASYMMETRY
Artículo1991 Contribution à l'étude pharmacodynamique d'un dérivé cétosulfoxyde (ω-méthylsufinyl α-acétothiophène). Action sur le SNC Annales Pharmaceutiques Françaises
Artículo1991 Contribution to the pharmacological study of a ketosulphoxide derivative (ω-methylsulphinyl α-acetothiophene): Activity at the CNS Annales Pharmaceutiques Françaises
Artículo1990 Beta-alanine potentiation of [h-3] flunitrazepam binding to rat spinal-cord homogenates Neuroscience Letters
Artículo1990 Synthesis and conformational analysis of 2-methylthio derivatives of l-(2-thienyl)ethanol and their o-methyl derivatives PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Artículo1989 Studies on conformation and configuration of beta-hydroxysulfoxides JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
Artículo1989 Synthesis and conformational-analysis of 2-methylthioderivatives of 1-(2'-furyl)ethanol and their o-methyl derivatives TETRAHEDRON
Artículo1989 The fixing role of the tert-butyl group in the conformational properties of acyclic sulfur-compounds - synthesis and conformational-analysis of 2-tert-butylthioderivatives of 1-phenylethanol and their o-methyl analogs TETRAHEDRON
Artículo1988 Asymmetric induction in the reduction of beta-cetosulfoxides by metal hydride ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA
Artículo1988 Configurational assignment of 2‐alkylsulphinyl‐1‐arylethanol diastereomers by 13C NMR Magnetic Resonance in Chemistry

Tesis dirigidas/tutorizadas:12
Fecha lectura Título Rol
24/11/2017 NUEVAS APROXIMACIONES MODULARES PARA LA SÍNTESIS ESTEREOSELECTIVA DE LIGANDOS QUIRALES BIDENTADOS Y COMPUESTOS DE INTERÉS FARMACOLÓGICO, A PARTIR DE N-TERC-BUTILSULFINILIMINAS Director/a
19/12/2014 DERIVADOS QUIRALES DE AZUFRE Y DE FÓSFORO: SÍNTESIS Y APLICACIONES EN CATÁLISIS ASIMÉTRICA Director/a
16/06/2014 LIGANDOS MIXTOS AZUFRE-FÓSFORO DERIVADOS DE CARBOHIDRATOS : SÍNTESIS Y APLICACIONES Director/a
19/12/2012 DISEÑO Y SÍNTESIS DE NUEVOS SULFÓXIDOS QUIRALES DE INTERÉS TERAPEÚTICO: ANTAGONISTAS DE LOS RECEPTORES NK1 Y ANÁLOGOS DEL FITOQUÍMICO SULFARAFANO Director/a
26/11/2012 NANOTUBOS DE CARBONO BIOCOMPATIBLES: SÍNTESIS Y APLICACIONES EN BIOMEDICINA Director/a
22/06/2012 UTILIZACIÓN DE LIGANDOS DERIVADOS DE CARBOHIDRATOS EN CATÁLISIS ASIMÉTRICA Y FUNCIONALIZACIÓN DE NANOPARTÍCULAS DE ORO CON CATALIZADORES ORGÁNICOS Y ORGANOMETÁLICOS Director/a
05/02/2010 Nuevas aplicaciones de los derivados quirales de Azufre: organocatálisis, síntesis enantioselectiva de calciomiméticos y acoplamiento de Suzuki - Miyaura Director/a
18/06/2009 Nuevos bionanomateriales: funcionalización biomimética de nanotubos de carbono con neoglicolípidos fotopolimerizables Director/a
30/01/2007 Ligandos S/S y S/P, derivados de carbohidratos: síntesis y aplicación en catálisis asimétrica Director/a
24/07/2003 Síntesis asimétrica de bis (sulfóxidos) y bis (tioglicósidos) con simetría C2. Aplicación como ligandos quirales en sustitución alílica catalizada por paladio Director/a
28/06/1999 Nuevas aplicaciones de N-sulfiniliminas: síntesis de aziridinas y aminoalcoholes ópticamente puros Director/a
2002 Nuevas reacciones de N-sulfiniliminas Director/a

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2022 31/12/2022 Responsable Nuevas estrategias para la optimización de la transferencia de quiralidad en procesos de interés sintético y terapéutico: Aproximaciones modulares para la síntesis de bissulfinilderivados enantiopuros (US-1381590) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
05/10/2021 30/06/2023 Responsable Fármacos multidiana estructuralmente relacionados con isotiocianatos naturales: diseño, síntesis y aplicaciones terapéuticas (P20_01171) Consejería de Economía, Conocimiento, Empresas y Universidad (Autonómico)
01/06/2020 31/05/2023 Responsable Los Carbohidratos y el Azufre como Herramientas Básicas en el Diseño y Síntesis de Nuevos Sistemas Moleculares Privilegiados de Interés Terapéutico y/o Sintético (PID2019-104767RB-I00) Ministerio de Ciencia, Innovación y Universidades (Nacional)
30/12/2016 31/12/2020 Responsable Desarrollo de Nuevos Sistemas Moleculares y Supramoleculares para una Catálisis Asimétrica Sostenible. Síntesis de Compuestos Antitumorales, Antivíricos y Antibacterianos (CTQ2016-78580-C2-2-R) Ministerio de Economía y Competitividad (Nacional)
01/01/2014 31/08/2017 Responsable Diseño y Síntesis de Nuevos Sistemas Moleculares y Supramoleculares Nanométricos como Herramientas Útiles en Síntesis Asimétrica y Biomedicina (CTQ2013-49066-C2-2-R) Ministerio de Economía y Competitividad (Nacional)
26/03/2013 31/03/2018 Responsable Nuevos Análogos del Sulforafano: Síntesis Enantioselectiva y Actividad Biológica. (P11-FQM-8046) Junta de Andalucía - Consejería de Innovación, Ciencia y Empresas (Autonómico)
01/01/2011 31/12/2014 Responsable Carbohidratos y Compuestos Quirales de Azufre: Aplicación para la Síntesis Estereoselectiva de Compuestos de Interés Biológico. (CTQ2010-21755-C02-02) Ministerio de Ciencia e Innovación (Nacional)
01/10/2007 30/06/2011 Investigador/a Aplicaciones de carbohidratos y derivados quirales de azufre en las síntesis estereolectivas de compuestos de interés terapéutico (CTQ2007-61185) Ministerio de Educación y Ciencia (Nacional)
13/04/2007 12/04/2010 Responsable Nuevos antagonistas de los receptores NK-1: diseño, síntesis y aplicación en el tratamiento contra el cáncer (P06-FQM-01852) Junta de Andalucía (Plan Andaluz de Investigación) (Autonómico)
13/12/2004 13/12/2007 Investigador/a Síntesis estereoselectivas a partir de organosulfurados y carbohidratos. Aplicaciones de interés terapéutico (CTQ2004-01057) Ministerio de Ciencia y Tecnología (Nacional)
28/12/2001 27/12/2004 Investigador/a Compuestos de interés terapéutico: síntesis estereoselectivas a partir de carbohidratos y compuestos de azufre (BQU2001-2425) Ministerio de Ciencia y Tecnología (Nacional)
01/10/1998 01/10/2001 Investigador/a SÍNTESIS ESTEREOSELECTIVAS Y PREPARACIÓN DE SUSTANCIAS CON ACTIVIDAD FARMACOLÓGICA POTENCIAL A TRAVÉS DE AMINOAZÚCARES Y COMPUESTO DE AZUFRE O FÓSFORO ÓPTICAMENTE ACTIVOS (PB97-0731)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/07/2021 31/08/2021 Responsable "Gram scale synthesis of Sulforaphane analogues EVG03, EVG06, EVG09 and EVG17" (4215/0115) EVGEN PHARMA PLC (Desconocido)
01/09/2016 31/08/2017 Responsable Asesoramiento para la Síntesis de Nano-Vector que carta con el principio activo Camptotecina (2870/0115) Nanosel, S.L. (Desconocido)
11/05/2016 31/05/2017 Responsable "Synthesis of Novel Sulforaphane Analogues" (2778/0115) EVGEN LIMITED (Desconocido)
01/11/2008 30/05/2009 Responsable Preparacón de Derivados del Glicerol (0179/0115) Befesa Gestión de Residuos Industriales S.L. (Desconocido)

Ayudas

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2005 31/12/2006 Responsable Solubilisation and specific delivery of carbon nanotubes into cancer cells (HF2004-0111) Ministerio de Educación y Ciencia (Nacional)
El investigador no tiene ningún resultado de investigación asociado