Miriam Echevarria Irusta

Catedrática de Universidad
irusta@us.es
Área de conocimiento: Fisiología
Departamento: Fisiología Médica y Biofísica
Grupo: Fisiopatología asociada a las Acuaporinas (CTS-1047)
Instituto de Inv.: IBIS
Prog. doctorado: Prog.Doct.en Biología Molecular, Biomedicina e Investigac.Clínica (RD.2011)
Tipo Año Título Fuente
Artículo2021 Aquaporin-4 Removal from the Plasma Membrane of Human Muller Cells by AQP4-IgG from Patients with Neuromyelitis Optica Induces Changes in Cell Volume Homeostasis: the First Step of Retinal Injury? MOLECULAR NEUROBIOLOGY
Artículo2021 Non-productive angiogenesis disassembles ASS plaque-associated blood vessels. NATURE COMMUNICATIONS
Artículo2019 AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis Cells
Artículo2019 Expression Pattern of Aquaporin 1 and Aquaporin 3 in Melanocytic and Nonmelanocytic Skin Tumors American journal of clinical pathology
Artículo2019 Expression patterns of aquaporin 1 in vascular tumours EUROPEAN JOURNAL OF DERMATOLOGY
Artículo2019 Predictive value of serum antibodies and point mutations of AQP4, AQP1 and MOG in a cohort of spanish patients with neuromyelitis optica spectrum disorders INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Artículo2018 Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Artículo2018 Long-term immunosuppression for CNS mouse xenotransplantation: Effects on nigrostriatal neurodegeneration and neuroprotective carotid body cell therapy XENOTRANSPLANTATION
Artículo2018 The Expression of AQP1 IS Modified in Lung of Patients With Idiopathic Pulmonary Fibrosis: Addressing a Possible New Target FRONTIERS IN MOLECULAR BIOSCIENCES
Ponencia2016 Antiparkinsonian cell therapy with carotid body is affected by age-related epigenetic regulation of hypoxic GDNF expression HUMAN GENE THERAPY
Artículo2016 Aquaporin-1 plays important role in proliferation by affecting cell cycle progression JOURNAL OF CELLULAR PHYSIOLOGY
Artículo2016 Chronic and progressive Parkinson's disease MPTP model in adult and aged mice JOURNAL OF NEUROCHEMISTRY
Artículo2016 Comparative Analysis for the Presence of IgG Anti-Aquaporin-1 in Patients with NMO-Spectrum Disorders INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Revisión2016 Role of aquaporins in cell proliferation: What else beyond water permeability? CHANNELS
Ponencia2015 Aquaporin-1 plays important role in proliferation by affecting cell cycle progression FEBS JOURNAL
Artículo2015 Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture PLOS ONE
Ponencia2014 Aging dependent GDNF induction by hypoxia in Carotid Body: Implications for antiparkinsonian cell therapy ACTA PHYSIOLOGICA
Artículo2014 An immunoassay that distinguishes real neuromyelitis optica signals from a labeling detected in patients receiving natalizumab BMC NEUROLOGY
Ponencia2014 Aquaporin-3 (AQP3) in cell proliferation, a potential target for therapeutic drugs ACTA PHYSIOLOGICA
Artículo2014 Expression of aquaporins in bronchial tissue and lung parenchyma of patients with chronic obstructive pulmonary disease Multidisciplinary Respiratory Medicine
Artículo2014 Functional Inhibition of Aquaporin-3 With a Gold-Based Compound Induces Blockage of Cell Proliferation JOURNAL OF CELLULAR PHYSIOLOGY
Ponencia2013 Aquoaporin-1 expression in idiopathic pulmonary fibrosis EUROPEAN RESPIRATORY JOURNAL
Artículo2013 Cellular overexpression of Aquaporins slows down the natural HIF-2 alpha. degradation during prolonged hypoxia GENE
Ponencia2013 Effect of a gold-based compound on AQP3 permeability and cell proliferation of tumor cells EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Artículo2013 Expresión de Aquaporinas en tejido pulmonar de pacientes con Enfermedad Pulmonar Obstructiva Crónica Revista Española de Patología
Artículo2013 Neuroprotective and reparative effects of carotid body grafts in a chronic MPTP model of Parkinson's disease NEUROBIOLOGY OF AGING
Ponencia2012 Aquaporin inhibition by a gold-based compound FEBS JOURNAL
Ponencia2012 Cell-based immuno assay for detection of AQP4-Abs in serum of patients with NMO FEBS JOURNAL
Ponencia2012 Overexpression or lack of AQP1 in the cell membrane modify cell proliferation associated to hypoxia FEBS JOURNAL
Artículo2012 Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound PLOS ONE
Ponencia2012 The gold-based compound Auphen affects proliferation rate of AQP3 expressing cells FEBS JOURNAL
Artículo2011 Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1 alpha PLOS ONE
Artículo2011 Overexpression of aquaporin-1 in lung adenocarcinomas and pleural mesotheliomas HISTOLOGY AND HISTOPATHOLOGY
Artículo2010 AQP1 mediates water transport in the carotid body PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Revisión2009 Aquaporins: Molecule revelation in cosmetic and cutaneous oncology Piel
Ponencia2009 Carotid Body GDNF Expression Is Differentially Regulated by Chronic Hypoxia and Intrastriatal Grafting Along Aging HUMAN GENE THERAPY
Ponencia2009 Interstitial Lung Disease but Not Chronic Obstructive Pulmonary Disease Alters the Expression Pattern of Aquaporin-1 in Human Lungs. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Ponencia2009 Overexpression of AQP1 in Lung Adenocarcinomas and Pleural Mesoendotheliomas. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Artículo2008 Shuttle walking versus maximal cycle testing: Clinical correlates in patients with kyphoscoliosis RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
Artículo2007 Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo2007 Protocolo de actuación en pacientes con displasia broncopulmonar/enfermedad pulmonar Crónica (y II) Acta pediátrica española
Artículo2007 Protocolo de actuación en pacientes con displasia broncopulmonar/enfermedad pulmonar crónica de la infancia (I) Acta pediátrica española
Artículo2006 ACUAPORINAS: LOS CANALES DE AGUA CELULARES Investigación y Ciencia
Artículo2006 Aquaporins in chicken: Localization of ck-AQP5 along the small and large intestine COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
Artículo2006 El volumen celular se regula por canales de agua-aquaporinas, proteínas integrales de la membrana celular Anales
Artículo2006 Neuroprotection by transgenic expression of glucose-6-phosphate dehydrogenase in dopaminergic nigrostriatal neurons of mice JOURNAL OF NEUROSCIENCE
Artículo2006 Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis WORLD JOURNAL OF GASTROENTEROLOGY
Artículo2006 The old water channels are aquaporin proteins throug which single files of water molecules cross cell membranes PHYSIOLOGICAL MINI-REVIEWS
Artículo2005 Rat adrenal chromaffin cells are neonatal CO2 sensors JOURNAL OF NEUROSCIENCE
Artículo2004 Induction of the glucose-6-phosphate dehydrogenase gene expression by chronic hypoxia in PC12 cells FEBS LETTERS
Artículo2003 Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats JOURNAL OF NEUROSCIENCE
Artículo2001 Identification of a new water channel (Rg-MIP) in the Malpighian tubules of the insect Rhodnius prolixus PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Ponencia2001 New membrane integral protein (RP-mip) in malpighian tubules (MT) of the insect Rhodnius prolixus and water secretion. BIOPHYSICAL JOURNAL
Ponencia2000 Aquaporins and water secretion pathways in upper malpighian tubules in Rhodnius prolixus JOURNAL OF PHYSIOLOGY-LONDON
Artículo1999 Detailed localization of aquaporin-4 messenger RNA in the CNS: Preferential expression in periventricular organs NEUROSCIENCE
Artículo1999 Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: Potential role in brain edema NEUROBIOLOGY OF DISEASE
Artículo1999 Localization of Aquaporin-3 mRNA and protein along the gastrointestinal tract of Wistar rats PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Artículo1999 Regulation of aquaporin mRNA expression in rat kidney by water intake JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Ponencia1999 The distribution of sodium channel isoform proteins in the mammalian PNS BIOPHYSICAL JOURNAL
Ponencia1998 Aquaporin 1 (AQP-1) selectivity filter BIOPHYSICAL JOURNAL
Artículo1998 Aquaporins JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
Ponencia1998 Localization of the mRNAs for several aquaporins along the gastrointestinal tract of rats JOURNAL OF PHYSIOLOGY-LONDON
Artículo1997 Length of the selectivity filter of aquaporin-1 BIOLOGY OF THE CELL
Artículo1997 Transport of water in proximal kidney tubules - From whole tubules to single channels: Length and section of the selectivity filter of aquaporin-1 WIENER KLINISCHE WOCHENSCHRIFT
Ponencia1997 Transport of water in proximal kidney tubules from whole tubules to single channels: Length and section of the selectivity filter of aquaporin-1 WIENER KLINISCHE WOCHENSCHRIFT
Ponencia1996 Localization of the human gene for aquaporin 3 (AQP3) to chromosome 9, region P12->P21, using fluorescent in situ hybridization. KIDNEY INTERNATIONAL
Artículo1996 Localization of the human gene for aquaporin 3 (AQP3) to chromosome 9, region p21->p12, using fluorescent in situ hybridization CYTOGENETICS AND CELL GENETICS
Artículo1996 Selectivity of the renal collecting duct water channel aquaporin-3 JOURNAL OF BIOLOGICAL CHEMISTRY
Artículo1995 Aquaporin-3 water channel localization and regulation in rat kidney AMERICAN JOURNAL OF PHYSIOLOGY-RENAL FLUID AND ELECTROLYTE PHYSIOLOGY
Artículo1995 AQUAPORIN-3 WATER CHANNEL LOCALIZATION AND REGULATION IN RAT-KIDNEY AMERICAN JOURNAL OF PHYSIOLOGY-RENAL FLUID AND ELECTROLYTE PHYSIOLOGY
Artículo1995 The proximal straight tubule (PST) basolateral cell membrane water channel: Selectivity characteristics JOURNAL OF MEMBRANE BIOLOGY
Artículo1995 THE PROXIMAL STRAIGHT TUBULE (PST) BASOLATERAL CELL-MEMBRANE WATER CHANNEL - SELECTIVITY CHARACTERISTICS JOURNAL OF MEMBRANE BIOLOGY
Artículo1994 CLONING AND EXPRESSION OF AQP3, A WATER CHANNEL FROM THE MEDULLARY COLLECTING DUCT OF RAT-KIDNEY PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Ponencia1994 IDENTIFICATION OF A NEW MEMBER OF THE MIP FAMILY OF PROTEINS IN RAT-KIDNEY PAPILLA FASEB JOURNAL
Ponencia1994 IMMUNOLOCALIZATION AND MOLECULAR-IDENTIFICATION OF CHIP28 WATER CHANNEL PROTEINS IN CORNEAL ENDOTHELIUM INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Artículo1994 Pathways for water absorption in isosmotic transporting epithelia. MOUNT SINAI JOURNAL OF MEDICINE
Artículo1994 PATHWAYS FOR WATER-ABSORPTION IN ISOSMOTIC TRANSPORTING EPITHELIA MOUNT SINAI JOURNAL OF MEDICINE
Ponencia1994 REGULATION AND SELECTIVITY OF A RAT COLLECTING DUCT WATER CHANNEL (WCH-30) JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Artículo1994 WATER AND UREA DIFFUSIVE PERMEABILITIES IN ISOLATED PROXIMAL TUBULE CELLS AMERICAN JOURNAL OF PHYSIOLOGY-RENAL FLUID AND ELECTROLYTE PHYSIOLOGY
Ponencia1993 Absorption of salt and water in the proximal tubule-revisited ISOTONIC TRANSPORT IN LEAKY EPITHELIA
Ponencia1993 BOVINE CORNEAL ENDOTHELIAL-CELLS EXPRESS CHIP28-TYPE WATER CHANNELS INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Ponencia1993 CORNEAL ENDOTHELIAL-CELLS EXPRESS CHIP28-TYPE WATER CHANNELS BIOPHYSICAL JOURNAL
Artículo1993 Cultured bovine corneal endothelial cells express CHIP28 water channels AMERICAN JOURNAL OF PHYSIOLOGY
Artículo1993 CULTURED BOVINE CORNEAL ENDOTHELIAL-CELLS EXPRESS CHIP28 WATER CHANNELS AMERICAN JOURNAL OF PHYSIOLOGY
Artículo1993 Determination of volume and water permeability of plated cells from measurements of light scattering AMERICAN JOURNAL OF PHYSIOLOGY
Artículo1993 DETERMINATION OF VOLUME AND WATER PERMEABILITY OF PLATED CELLS FROM MEASUREMENTS OF LIGHT-SCATTERING AMERICAN JOURNAL OF PHYSIOLOGY
Artículo1993 EXPRESSION OF MULTIPLE WATER CHANNEL ACTIVITIES IN XENOPUS-OOCYTES INJECTED WITH MESSENGER-RNA FROM RAT-KIDNEY JOURNAL OF GENERAL PHYSIOLOGY
Ponencia1993 INTERMITTENT HYPEROSMOTIC UREA SHOCKS TRIGGER A (CA2+)I-RELATED NA-K-2C1 COTRANSPORT IN KIDNEY PROXIMAL TUBULE CELLS BIOPHYSICAL JOURNAL
Ponencia1993 WATER-DEPRIVATION INCREASES THE EXPRESSION IN XENOPUS OOCYTES OF A RAT-KIDNEY PAPILLA WATER CHANNEL FASEB JOURNAL
Ponencia1992 CONTRALUMINAL CELL-MEMBRANE WATER CHANNELS IN PST EXCLUDE UREA AND ACETAMIDE BUT ARE FORMAMIDE PERMEABLE FASEB JOURNAL
Ponencia1992 EVIDENCE FOR THE PRESENCE OF WATER CHANNELS IN BOVINE CORNEAL ENDOTHELIAL-CELLS FASEB JOURNAL
Artículo1992 OPTICAL MEASUREMENT OF OSMOTIC WATER TRANSPORT IN CULTURED-CELLS - ROLE OF GLUCOSE TRANSPORTERS JOURNAL OF GENERAL PHYSIOLOGY

Proyectos de Investigación

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/01/2007 31/12/2012 Investigador/a Sensibilidad al oxígeno y neurodegeneración (CONFMB-001/2006) Fundación Marcelino Botín (Nacional)
01/01/2013 31/12/2016 Responsable Estudio del papel de AQP1 en el desarrollo de la hidrocefalia asociada a hipoxia cerebral (PI12/01882) Ministerio de Economía y Competitividad (Instituto de Carlos III) (Nacional)

Contratos

Fecha de inicio Fecha de fin Rol Denominación Agencia financiadora
01/06/2010 31/12/2010 Investigador/a Estudio del potencial efecto neuroprotector in vivo de un compuesto de Noscira. (0798/0321) NOSCIRA, S.A. (Nacional)
14/04/2003 31/12/2003 Responsable Investigación dentro de las líneas de investigación del laboratorio de investigaciones biomédicas (SI-057/03) Hospital Universitario Virgen del Rocío (Local)
17/01/2011 31/12/2011 Responsable Investigación dentro de las líneas del Laboratorio de Investigaciones Biomédicas. (1095/0299) S.A.S. Hospital Universitario Virgen del Rocío (Local)
07/06/2004 31/12/2004 Responsable Investigación dentro de las líneas de investigación del laboratorio del investigaciones biomédicas (SI-051/04) Hospital Universitario Virgen del Rocío (Local)
01/06/2011 31/12/2011 Responsable Investigación dentro de líneas del Laboratorio de Investigaciones Biométicas. (1417/0299) Hospital Universitario Virgen del Rocío (Local)
07/07/2005 31/12/2005 Responsable Investigación dentro de las líneas de investigación del laboratorio de investigaciones biomédicas (SI-062/05) Hospital Universitario Virgen del Rocío (Local)
07/07/2006 31/12/2006 Responsable Investigación dentro de las líneas de investigación del laboratorio de investigaciones biomédicas (SI-077/06) Hospital Universitario Virgen del Rocío (Local)
07/07/2007 31/12/2007 Responsable Investigación dentro de las líneas de investigación del laboratorio de investigaciones biomédicas (SI-100/07) Hospital Universitario Virgen del Rocío (Local)
01/01/2010 31/03/2010 Investigador/a Determinación de la eficacia de un compuesto de NOSCIRA tras administración crónica en un modelo murino de muerte neuronal inducida por MPTP (0639/0321) NOSCIRA, S.A. (Nacional)
10/06/2002 31/12/2002 Responsable Investigación dentro de las líneas de investigación del laboratorio de investigaciones biomédicas (SI-050/02) Hospital Universitario Virgen del Rocío (Local)