Terapias Basadas en Glicomiméticos para el Tratamiento de Enfermedades de Plegamiento de Proteínas, Inflamación y Cáncer.

Referencia: SAF2016-76083-R

Tipo: Proyecto de investigación
Programa financiador: Plan Estatal 2013-2016 Retos - Proyectos I+D+i
Entidad financiadora: Ministerio de Economía y Competitividad
Ámbito: Nacional
Convocatoria competitiva:
Fecha de inicio: 30/12/2016
Fecha de fin: 31/12/2020
Participantes en la financiación
Nombre Rol
Ortiz Mellet, Carmen Responsable
Gallego Yerga, Laura Investigador/a
Schaeffer, Evelyne Investigador/a
Ortega Caballero, Fernando Investigador/a
García Moreno, María Isabel Investigador/a
Rodríguez Gil, Antonio Investigador/a
Katsumi, Higaki Investigador/a
Sánchez Fernández, Elena Matilde Investigador/a
Jiménez Blanco, José Luis Investigador/a
Cienfuegos Rodríguez, Silvia Investigador/a
Publicaciones relacionadas
Tipo Año Título Fuente
Artículo 2020 Amplified Detection of Breast Cancer Autoantibodies Using MUC1-Based Tn Antigen Mimics JOURNAL OF MEDICINAL CHEMISTRY
Artículo 2020 Carbohydrate supramolecular chemistry: beyond the multivalent effect CHEMICAL COMMUNICATIONS
Artículo 2020 Click synthesis of size- and shape-tunable star polymers with functional macrocyclic cores for synergistic DNA complexation and delivery BIOMACROMOLECULES
Capítulo 2020 sp2-Iminosugars as chemical mimics for glycodrug design Small molecule drug discovery: methods, molecules and applications
Artículo 2020 Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment CHEMICAL SCIENCE
Artículo 2020 Tuning the Topological Landscape of DNA–Cyclodextrin Nanocomplexes by Molecular Design CHEMISTRY-A EUROPEAN JOURNAL
Artículo 2019 Dynamic Control of the Self-Assembling Properties of Cyclodextrins by the Interplay of Aromatic and Host-Guest Interactions FRONTIERS IN CHEMISTRY
Artículo 2019 Multiply-linked cyclodextrin-aromatic hybrids: Caps, hinges and clips JOURNAL OF CARBOHYDRATE CHEMISTRY
Artículo 2019 Pharmacological Chaperones for the Treatment of alpha-Mannosidosis JOURNAL OF MEDICINAL CHEMISTRY
Artículo 2019 sp(2)-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Artículo 2019 Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp(2)-Iminosugar Glycolipids MOLECULES
Artículo 2019 Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties CHEMICAL COMMUNICATIONS
Artículo 2018 Catalyst-Free Synthesis of Alkylpolyglycosides Induced by High-Frequency Ultrasound CHEMSUSCHEM
Artículo 2018 Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell CHEMISTRY-A EUROPEAN JOURNAL
Artículo 2018 Plasmid-Templated Control of DNA-Cyclodextrin Nanoparticle Morphology through Molecular Vector Design for Effective Gene Delivery CHEMISTRY-A EUROPEAN JOURNAL
Artículo 2018 Probing the Inhibitor versus Chaperone Properties of sp(2)-Iminosugars towards Human beta-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease MOLECULES
Artículo 2018 The sp(2)-iminosugar glycolipid 1-dodecylsulfony1-5N,6O-oxomethylidenenojirimycin (DSO2-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants FOOD AND CHEMICAL TOXICOLOGY
Artículo 2018 Xylylene Clips for the Topology-Guided Control of the Inclusion and Self-Assembling Properties of Cyclodextrins JOURNAL OF ORGANIC CHEMISTRY
Artículo 2017 A novel potential nanophototherapeutic based on the assembly of an amphiphilic cationic beta-cyclodextrin and an anionic porphyrin JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
Artículo 2017 Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cells BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Artículo 2017 Carbon Dioxide as a Traceless Caramelization Promotor: Preparation of Prebiotic Difructose Dianhydrides (DFAs)-Enriched Caramels from D-Fructose JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Artículo 2017 Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers JOURNAL OF MATERIALS CHEMISTRY B
Artículo 2017 Docetaxel-Loaded Nanoparticles Assembled from beta-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells FRONTIERS IN PHARMACOLOGY
Artículo 2017 Fluorinated Chaperone-beta-Cyclodextrin Formulations for beta-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease JOURNAL OF MEDICINAL CHEMISTRY
Artículo 2017 Molecular determinants for cyclooligosaccharide-based nanoparticle-mediated effective siRNA transfection NANOMEDICINE
Revisión 2017 Molecular nanoparticle-based gene delivery systems JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
Artículo 2017 Multivalency as an action principle in multimodal lectin recognition and glycosidase inhibition: a paradigm shift driven by carbon-based glyconanomaterials JOURNAL OF MATERIALS CHEMISTRY B
Artículo 2017 sp(2)-Iminosugar -glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, 1-integrin, and FAK signaling pathways JOURNAL OF CELLULAR PHYSIOLOGY
Artículo 2017 Synthesis of beta-galactosylamides as ligands of the peanut lectin. Insights into the recognition process CARBOHYDRATE RESEARCH
Artículo 2017 The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study CHEMISTRY-A EUROPEAN JOURNAL
Nota: la fuente de financiación de las publicaciones se ha obtenido de WOS