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Bases genéticas y moleculares de la inestabilidad genómica y su relación con la biogénesis de los mRNPs de eucariotas

Referencia: BFU2006-05260

Tipo: Proyecto de investigación
Programa financiador: Plan Nacional del 2006
Entidad financiadora: Ministerio de Educación y Ciencia
Ámbito: Nacional
Convocatoria competitiva:
Fecha de inicio: 01/10/2006
Fecha de fin: 30/09/2011
Participantes en la financiación
Nombre Rol
Aguilera López, Andrés Responsable
Luna Varo, Rosa María Investigador/a
Ruiz Pérez, José Francisco Investigador/a
Gómez González, Belén Investigador/a
González Aguilera, Cristina Investigador/a
Moriel Carretero, María Anajara Investigador/a
Muñoz Galván, Sandra Investigador/a
Tous Rivera, Cristina Investigador/a
Gaillard, Hélène Investigador/a
Cortés Ledesma, Felipe Investigador/a
García Rubio, María Luisa Investigador/a
Felipe Abrio, Irene Investigador/a
García Muse, Tatiana Beatriz Investigador/a
Herrera Moyano, Emilia Investigador/a
Castellano Pozo, Maikel Investigador/a
Jimeno González, Sonia Investigador/a
Gavalda Martín, Sandra Investigador/a
Pardo, Benjamín Investigador/a
Escalante Martín, Francisco Javier Contratado
Barroso Ceballos, Sonia Inés Contratado
Gaillard, Hélène Contratado
Jimeno González, Sonia Contratado
García Rubio, María Luisa Contratado
Cooper, Zoë Contratado
García Muse, Tatiana Beatriz Contratado
Gómez González, Belén Contratado
Pérez García, Loida Contratado
Martín-Niclos Morales, María José Contratado
Galindo Díaz, Ulises Jesús Contratado
Lafuente Barquero, Juan Francisco Contratado
Ruiz Pérez, José Francisco Contratado
Muñoz Galván, Sandra Contratado
Durán Rodríguez, Luis Contratado
Tous Rivera, Cristina Contratado
Publicaciones relacionadas
Tipo Año Título Fuente
Artículo 2012 Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor EMBO JOURNAL
Artículo 2012 Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases PLOS GENETICS
Artículo 2012 R-loops cause replication impairment and genome instability during meiosis EMBO REPORTS
Artículo 2012 Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes NUCLEIC ACIDS RESEARCH
Artículo 2011 A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors EMBO JOURNAL
Artículo 2011 AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants PLOS GENETICS
Artículo 2011 Genome instability and transcription elongation impairment in human cells depleted of THO/TREX PLOS GENETICS
Artículo 2011 Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles EMBO JOURNAL
Artículo 2011 Nab2 functions in the metabolism of RNA driven by polymerases II and III MOLECULAR BIOLOGY OF THE CELL
Artículo 2011 New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation MOLECULAR AND CELLULAR BIOLOGY
Artículo 2011 The Rad50 coiled-coil domain is indispensable for Mre11 complex functions NATURE STRUCTURAL & MOLECULAR BIOLOGY
Artículo 2011 The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores CELL
Artículo 2011 Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability MOLECULAR CELL
Artículo 2009 Chromosomal Translocations Caused by Either Pol32-Dependent or Pol32-Independent Triparental Break-Induced Replication MOLECULAR AND CELLULAR BIOLOGY
Artículo 2009 Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair PLOS GENETICS
Artículo 2009 R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX NUCLEIC ACIDS RESEARCH
Artículo 2009 Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery JOURNAL OF CELL BIOLOGY
Artículo 2009 Stimulation of direct-repeat recombination by RNA polymerase III transcription DNA REPAIR
Artículo 2009 The Dot1 Histone Methyltransferase and the Rad9 Checkpoint Adaptor Contribute to Cohesin-Dependent Double-Strand Break Repair by Sister Chromatid Recombination in Saccharomyces cerevisiae GENETICS
Artículo 2009 The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants MOLECULAR AND CELLULAR BIOLOGY
Artículo 2009 The Stress-activated Protein Kinase Hog1 Mediates S Phase Delay in Response to Osmostress MOLECULAR BIOLOGY OF THE CELL
Artículo 2008 A Novel Class of mRNA-containing Cytoplasmic Granules Are Produced in Response to UV-Irradiation MOLECULAR BIOLOGY OF THE CELL
Artículo 2008 The THP1-SAC3-SUS1-CDC31 Complex Works in Transcription Elongation-mRNA Export Preventing RNA-mediated Genome Instability MOLECULAR BIOLOGY OF THE CELL
Nota: la fuente de financiación de las publicaciones se ha obtenido de WOS